IE1

Immediate-early protein 3

611 amino acids

Strong transcriptional activator of the E1 promoter, shows an autoregulatory function by repression of the IE1/IE3 promoter. The IE1 protein has some additive effect on the trans-activating properties of the IE3 protein.

68.103 kDa

MEPAAPSCNMIMIADQASVNAHGRHLDENRVYPSDKVPAHVANKILESGTETVRCDLTLEDMLGDYEYDDPTEEEKILMDRIADHVGNDNSDMAIKHAAGPEMNIDIVTAAASMSGITTASHSALPIRRPNTPDFRRHSEKKAKKHKNKQRQRLDDVVAKLHKPSESEADEDFIFQQPQEEEYQEEQEPQVISSSPQHFDERSPSRSSSDHGGHSGGNSRDGQFYLSSGSEDEDDEDDERVDSGYRGSSRSEDSSRYRPHGGSHSSRSSIKSSGSGSSRHHHKRKAVPERHHPFTPPSAKRYAAAAPSSRYECPVRVDSSDSDDAPTMVQRGTLKIKSFRPPSSGSNSNKHSSSSGGSTSSSHKKQQQQQAPSKKPVMSSGSDKIRDMVDRTAGGYVAPNAHKKCREDKSRKYPARALEYKNLPFRPQSPQYLLGKAIQFCKEETVHDKFIMLFYTRSQDVRKAVDETRARMGMRPNLSISCPFMTEHTKPINHSRETIDRTSAACTAGTQAVWDMEERRGQKCVPRTSDYRSMIIQAANPPDFLGAVKTCLHLSQVFPKQVCMRLCSITGGLNPLPIYEETVSSYVNAQFEADDISHHEDESGEYESDCE

IE1

Immediate-early protein 1

595 amino acids

The IE1 protein has some additive effect on the trans-activating properties of the IE3 protein.

66.709 kDa

MEPAAPSCNMIMIADQASVNAHGRHLDENRVYPSDKVPAHVANKILESGTETVRCDLTLEDMLGDYEYDDPTEEEKILMDRIADHVGNDNSDMAIKHAAVRSVLLSCKIAHLMIKQNYQSAINSATNILCQLANDIFERIERQRKMIYGCFRSEFDNVQLGRLMYDMYPHFMPTNLGPSEKRVWMSYVGEAIVAATNIDHALDERAAWAKTDCSLPGEFKPELCVLVGAIRRLHDPPCYTKPFLDAKSQLAVWQQMKAIESESVSTHVVVVEALKLRENLAKAVQETIAYERHQYHRVCQMMCNNMKDHLETTCMLARGRTLATLADLRSTRYNLALFLLSEMHIFDSFTMPRIRGAMKQARCMSYVERTISLAKFRELADRVHNRSAPSPQGVIEEQQQAGEEEQQQQQEIEYDPEMPPLEREEEQEDEQVEEEPPADEEEGGAVGGVTQEEPAGEATEEAEEDESQPGPSDNQVVPESSETPTPAEDEETQSADEGESQELEGSQQLILSRPAAPLTDSETDSDSEDDDEVTRIPVGFSLMTSPVLQPTTRSATAAASSGTAPRPALKRQYAMVHTRSKSSENQQQPKKKSKK

IE1

Trans-activating transcriptional regulatory protein

587 amino acids

Regulatory transcriptional protein, which trans-activates gene expression from early baculovirus promoters. Can also trans-activate its own promoter, suggesting that it is autoregulated during normal infection of insect cells.

Belongs to the nucleopolyhedrovirus IE-1 protein family.

67.496 kDa

MTQINFNASYTSAPTPSRASFDNGYSEFCDKQQPNDYLNYYNNPTPDGADTVVSDSRLQAASNFLASVNSLTDDNDIMECLLKTTDNLGEAVSSAYNAESFELPVAEQPSPSSAYNAESFEHPVGVNQPSATGTKRKLDEYLDDSQSVVGQFNKNKLKPKYKKSTIQSCATLEQTINHNTNICTVASTQEITHYFTNDFAPYLMRFDDNDYNSNRFSDHMSETGYYMFVVKKSEVKPFEIIFAKYVSNVVYEYTNNYYMVDNRVFVVTFDKIRFMISYNLVKETGIEIPHSQDVCNDETAAQNCKKCHFVDVHHTFKAALTSYFNLDMYYAQTTFVTLLQSLGERKCGFLLSKLYEMYQDKNLFTLPIMLSRKESNEIETASNNFFVSPYVSQILKYSESIRKVKFPDNPPNKYVVDNLNLIVNKKSTLTYKYSSVANLLFNNYKYHDNIASNNNAENLKKVKKEDGSMHIVEQYLTQNVDNVKGHNFIVLSFKNEERLTIAKKNEEFYWISGEIKDVDASQVIQKYNRFKHHMFVISKVNRRESTTLHNNLLKLLALILQGLVPLSDAITFAEQKLNCKYKKFEFN

IE1

Trans-activating transcriptional regulatory protein

582 amino acids

Regulatory transcriptional protein, which trans-activates gene expression from early baculovirus promoters. Can also trans-activate its own promoter, suggesting an autoregulation during infection of host cells. Promotes also viral DNA genome replication via the N-terminal region.

Belongs to the nucleopolyhedrovirus IE-1 protein family.

66.881 kDa

MTQINFNASYTSASTPSRASFDNSYSEFCDKQPNDYLSYYNHPTPDGADTVISDSETAAASNFLASVNSLTDNDLVECLLKTTDNLEEAVSSAYYSESLEQPVVEQPSPSSAYHAESFEHSAGVNQPSATGTKRKLDEYLDNSQGVVGQFNKIKLRPKYKKSTIQSCATLEQTINHNTNICTVASTQEITHYFTNDFAPYLMRFDDNDYNSNRFSDHMSETGYYMFVVKKSEVKPFEIIFAKYVSNVVYEYTNNYYMVDNRVFVVTFDKIRFMISYNLVKETGIEIPHSQDVCNDETAAQNCKKCHFVDVHHTFKAALTSYFNLDMYYAQTTFVTLLQSLGERKCGFLLSKLYEMYQDKNLFTLPIMLSRKESNEIETASNNFFVSPYVSQILKYSESVQFPDNPPNKYVVDNLNLIVNKKSTLTYKYSSVANLLFNNYKYHDNIASNNNAENLKKVKKEDGSMHIVEQYLTQNVDNVKGHNFIVLSFKNEERLTIAKKNKEFYWISGEIKDVDVSQVIQKYNRFKHHMFVIGKVNRRESTTLHNNLLKLLALILQGLVPLSDAITFAEQKLNCKYKKFEFN

IE1

Trans-activating transcriptional regulatory protein

560 amino acids

Regulatory transcriptional protein, which trans-activates gene expression from early baculovirus promoters. Can also trans-activate its own promoter, suggesting that it is autoregulated during normal infection of insect cells.

Belongs to the nucleopolyhedrovirus IE-1 protein family.

64.946 kDa

MPKNMAALQQSLYTGPSTPSHTQFSRSTEFPENLNFDVLNDSYETFSSVSLTTAEQDNQIDKILQESAAMNRDVNSELAQFTASEYVTGFRADTMEPEVIVETIGDSMKRKASELDSDSDSGESSKGKKRVIKPKMRQRYKKATIQNKTSLTEECNYNTEICTVAPTDQIAEYFKHDFSVYLEKQKSDCQMSANRFSDYISETGYYVFVVKKSEHKPFEVVFAKFVNNVTNEYTNNYYMVDNRVFVVSLNNVKFMVSYKLVREQGIDIPPHVNLCDDAQAERNPYDCYFEPVKNVFQTTLINHFHLDMYYSQTTFVTLMQSMGESKSGMLLNKLYQMFQDRSLFTLPIMLSRKEPTIENTPLSRNYTSSYVAQIIKYSKNVRFPENNPDNGVISRLEEIVTQKSSLTYKYSSVANLLFSRYGHQRDNNADSLKKVKKEDGNRLLVEQYMSQNENDETSHNFIVLQFGGVNDERLTIAKKGIEFFWIAAEIKDINVDDLVKKYTRNVHHVFRIINVNRRESTTWHNNLLKLLQLLLQNLIRIDDVQQYSNKGDSKFIYKRL

IE1

Trans-activating transcriptional regulatory protein

560 amino acids

Regulatory transcriptional protein, which trans-activates gene expression from early baculovirus promoters. Can also trans-activate its own promoter, suggesting that it is autoregulated during normal infection of insect cells.

Belongs to the nucleopolyhedrovirus IE-1 protein family.

64.316 kDa

MPKNMETLQRSYMGPSTPNHNLFNNATELPDDLNFSTMDVPYDGSMPMNMSSDSLMNLLEDRSKKLACAVDTELARESTASEFVAGFSADSPQAQLAETGAETGAAGGSKRKASEVDSDSDSDDSSKGKKLVNKPKIRQRYKKATIQNRTSLTEERQYSTEICTVAAPDQIAKYFAQDFSAHLNEVKSECQMSANRFSDYISETGYYVFVVKKGDRKPFEVVFAKFVNNATNEYTNNYYMVDNRVFVVSLNNVKFMVSYKLVREQGIDIPPHVNLCNDAQAERTPLNCYFEPVKNAFQATLINHFHLDMFYAQTTFVTLMQAVGENKTNMLLNKLYQMYQDRSLFTLPIMLSRKEPVNENAPQNKNHAFSYVAQIMKYSKNLRFPQGDPTQQVMDRLEEIVTQKSSLTYKYSSVANLLFNRYGRRDNNADALKKVKKEDGNRLLVEQYMSYNENDDTSHNFIVLQFGGVNDERLTIAKRGKEFYWIAGEIKDISVDDLIKKYARNVHHVFRIINVNRRESTTWHNNLLKLLQLLLQNLIRLEDVQRYSDKSDTKFVYKKV

IE1

Probable E3 ubiquitin-protein ligase IE1

285 amino acids

Controls the expression of later classes of genes and also of the IE genes (Potential). E3 ubiquitin-protein ligase (Probable). E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.

32.693 kDa

MASKDSDVRCVKCQSLKPTTPLTGQDRCARCVAINELKPWISTCNINPCYDGDLSESNETIEMMDINSCREDTPSDAESETRFMPFVAHSKQPKHTSKNPTKGEIQYFPVEKCKDIHRVENQSSIDEEGKQCWICRDGESLPEARYCNCYGDLQYCHEECLKTWISMSGEKKCKFCQTPYKVNRQLSLKRGLPGYWDRDDRFVFIAGFIGMGTILAGWIASFFYLLVVLCGKYFTYKDVMIVVGGLAIIQVVGLMFSLFMYFQIGNLLRQYINYMTETNIDPLRT