Protein
RxLR effector protein Htp1
Organism
Saprolegnia parasitica (strain CBS 223.65)
Function
Effector involved in the disease saprolegniosis in salmonids and other freshwater fish, resulting in considerable economic losses in aquaculture (Probable). Within the host fish cells, Htp1 is involved in the uptake of the S.parasitica effector Htp3 at a neutral pH (pH 7.5) and its release from vesicles into host cytosol where it degrades nucleic acids (PubMed:29904064).
Similarity
Belongs to the RxLR effector family.
Sequence
MRIHHPLTLAALCVVLHESLGAAQHSNNVARLEHYRIAEIEHWEKRHLRSDSRGHRHHAHHGQVIDKENNNSQEQATTGNSVETNQVPSTEPTKDKTTPMKNALFKLFREKKLKTKNAGNGHAHDDDDDSDFSDDDVPTNAPTDAPTGAPTDAPTDAPTVAPTDAPTDAPTEAPTNAPTGTDAPTDAPTDAQVVPTFD