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HST

Gene
HST
Protein
Shikimate O-hydroxycinnamoyltransferase
Organism
Nicotiana tabacum
Length
435 amino acids
Function
Acyltransferase involved in the biosynthesis of lignin. The affinity for shikimate as acceptor is 100-fold higher than for quinate. The most efficient donors are caffeoyl-CoA > p-coumaroyl-CoA > feruloyl-CoA >> sinapoyl-CoA.
Similarity
Belongs to the plant acyltransferase family.
Mass
48.265 kDa
Sequence
MKIEVKESTMVKPAAETPQQRLWNSNVDLVVPNFHTPSVYFYRPTGSPNFFDGKVLKEALSKALVPFYPMAGRLCRDEDGRIEIDCKGQGVLFVEAESDGVVDDFGDFAPTLELRQLIPAVDYSQGIQSYALLVLQITHFKCGGVSLGVGMQHHAADGASGLHFINTWSDMARGLDLTIPPFIDRTLLRARDPPQPQFPHVEYQPPPTLKVTPENTPISEAVPETSVSIFKLTRDQINTLKAKSKEDGNTVNYSSYEMLAGHVWRSTCMARGLAHDQETKLYIATDGRSRLRPSLPPGYFGNVIFTTTPIAVAGDIQSKPIWYAASKLHDALARMDNDYLRSALDYLELQPDLKALVRGAHTFKCPNLGITSWSRLPIHDADFGWGRPIFMGPGGIAYEGLSFILPSPTNDGSQSVAISLQAEHMKLFEKFLYDF

Gene
HST
Protein
Shikimate O-hydroxycinnamoyltransferase
Organism
Nicotiana tabacum
Length
435 amino acids
Function
Acyltransferase involved in the biosynthesis of lignin. The affinity for shikimate as acceptor is 100-fold higher than for quinate. The most efficient donors are caffeoyl-CoA > p-coumaroyl-CoA > feruloyl-CoA >> sinapoyl-CoA.
Similarity
Belongs to the plant acyltransferase family.
Mass
48.265 kDa
Sequence
MKIEVKESTMVKPAAETPQQRLWNSNVDLVVPNFHTPSVYFYRPTGSPNFFDGKVLKEALSKALVPFYPMAGRLCRDEDGRIEIDCKGQGVLFVEAESDGVVDDFGDFAPTLELRQLIPAVDYSQGIQSYALLVLQITHFKCGGVSLGVGMQHHAADGASGLHFINTWSDMARGLDLTIPPFIDRTLLRARDPPQPQFPHVEYQPPPTLKVTPENTPISEAVPETSVSIFKLTRDQINTLKAKSKEDGNTVNYSSYEMLAGHVWRSTCMARGLAHDQETKLYIATDGRSRLRPSLPPGYFGNVIFTTTPIAVAGDIQSKPIWYAASKLHDALARMDNDYLRSALDYLELQPDLKALVRGAHTFKCPNLGITSWSRLPIHDADFGWGRPIFMGPGGIAYEGLSFILPSPTNDGSQSVAISLQAEHMKLFEKFLYDF

Gene
HST
Protein
Shikimate O-hydroxycinnamoyltransferase
Organism
Arabidopsis thaliana
Length
433 amino acids
Function
Acyltransferase involved in the biosynthesis of lignin (PubMed:15161961, PubMed:26858288). Accepts caffeoyl-CoA and p-coumaroyl-CoA as substrates and transfers the acyl group on both shikimate and quinate acceptors (PubMed:15161961).
Similarity
Belongs to the plant acyltransferase family.
Mass
47.975 kDa
Sequence
MKINIRDSTMVRPATETPITNLWNSNVDLVIPRFHTPSVYFYRPTGASNFFDPQVMKEALSKALVPFYPMAGRLKRDDDGRIEIDCNGAGVLFVVADTPSVIDDFGDFAPTLNLRQLIPEVDHSAGIHSFPLLVLQVTFFKCGGASLGVGMQHHAADGFSGLHFINTWSDMARGLDLTIPPFIDRTLLRARDPPQPAFHHVEYQPAPSMKIPLDPSKSGPENTTVSIFKLTRDQLVALKAKSKEDGNTVSYSSYEMLAGHVWRSVGKARGLPNDQETKLYIATDGRSRLRPQLPPGYFGNVIFTATPLAVAGDLLSKPTWYAAGQIHDFLVRMDDNYLRSALDYLEMQPDLSALVRGAHTYKCPNLGITSWVRLPIYDADFGWGRPIFMGPGGIPYEGLSFVLPSPTNDGSLSVAIALQSEHMKLFEKFLFEI

Gene
HST
Protein
Shikimate O-hydroxycinnamoyltransferase
Organism
Arabidopsis thaliana
Length
433 amino acids
Function
Acyltransferase involved in the biosynthesis of lignin (PubMed:15161961, PubMed:26858288). Accepts caffeoyl-CoA and p-coumaroyl-CoA as substrates and transfers the acyl group on both shikimate and quinate acceptors (PubMed:15161961).
Similarity
Belongs to the plant acyltransferase family.
Mass
47.975 kDa
Sequence
MKINIRDSTMVRPATETPITNLWNSNVDLVIPRFHTPSVYFYRPTGASNFFDPQVMKEALSKALVPFYPMAGRLKRDDDGRIEIDCNGAGVLFVVADTPSVIDDFGDFAPTLNLRQLIPEVDHSAGIHSFPLLVLQVTFFKCGGASLGVGMQHHAADGFSGLHFINTWSDMARGLDLTIPPFIDRTLLRARDPPQPAFHHVEYQPAPSMKIPLDPSKSGPENTTVSIFKLTRDQLVALKAKSKEDGNTVSYSSYEMLAGHVWRSVGKARGLPNDQETKLYIATDGRSRLRPQLPPGYFGNVIFTATPLAVAGDLLSKPTWYAAGQIHDFLVRMDDNYLRSALDYLEMQPDLSALVRGAHTYKCPNLGITSWVRLPIYDADFGWGRPIFMGPGGIPYEGLSFVLPSPTNDGSLSVAIALQSEHMKLFEKFLFEI

Gene
HST
Protein
Homogentisate solanesyltransferase, chloroplastic
Organism
Arabidopsis thaliana
Length
386 amino acids
Function
Involved in the synthesis of plastoquinone-9. Can use both homogentisic acid and 2,5-dihydroxyphenylacetic acid gamma-lactone as prenyl acceptors, and solanesyl diphosphate > farnesyl diphosphate > geranylgeranyl diphosphate >> phytyl diphosphate as prenyl donors. Do not catalyze the decardoxylation of homogentisate uncoupled from prenylation.
Similarity
Belongs to the UbiA prenyltransferase family.
Mass
42.841 kDa
Sequence
MELSISQSPRVRFSSLAPRFLAASHHHRPSVHLAGKFISLPRDVRFTSLSTSRMRSKFVSTNYRKISIRACSQVGAAESDDPVLDRIARFQNACWRFLRPHTIRGTALGSTALVTRALIENTHLIKWSLVLKALSGLLALICGNGYIVGINQIYDIGIDKVNKPYLPIAAGDLSVQSAWLLVIFFAIAGLLVVGFNFGPFITSLYSLGLFLGTIYSVPPLRMKRFPVAAFLIIATVRGFLLNFGVYHATRAALGLPFQWSAPVAFITSFVTLFALVIAITKDLPDVEGDRKFQISTLATKLGVRNIAFLGSGLLLVNYVSAISLAFYMPQVFRGSLMIPAHVILASGLIFQTWVLEKANYTKEAISGYYRFIWNLFYAEYLLFPFL

Gene
HST
Protein
Homogentisate solanesyltransferase, chloroplastic
Organism
Arabidopsis thaliana
Length
386 amino acids
Function
Involved in the synthesis of plastoquinone-9. Can use both homogentisic acid and 2,5-dihydroxyphenylacetic acid gamma-lactone as prenyl acceptors, and solanesyl diphosphate > farnesyl diphosphate > geranylgeranyl diphosphate >> phytyl diphosphate as prenyl donors. Do not catalyze the decardoxylation of homogentisate uncoupled from prenylation.
Similarity
Belongs to the UbiA prenyltransferase family.
Mass
42.841 kDa
Sequence
MELSISQSPRVRFSSLAPRFLAASHHHRPSVHLAGKFISLPRDVRFTSLSTSRMRSKFVSTNYRKISIRACSQVGAAESDDPVLDRIARFQNACWRFLRPHTIRGTALGSTALVTRALIENTHLIKWSLVLKALSGLLALICGNGYIVGINQIYDIGIDKVNKPYLPIAAGDLSVQSAWLLVIFFAIAGLLVVGFNFGPFITSLYSLGLFLGTIYSVPPLRMKRFPVAAFLIIATVRGFLLNFGVYHATRAALGLPFQWSAPVAFITSFVTLFALVIAITKDLPDVEGDRKFQISTLATKLGVRNIAFLGSGLLLVNYVSAISLAFYMPQVFRGSLMIPAHVILASGLIFQTWVLEKANYTKEAISGYYRFIWNLFYAEYLLFPFL

Gene
HST
Protein
Homogentisate solanesyltransferase, chloroplastic
Organism
Chlamydomonas reinhardtii
Length
370 amino acids
Function
Involved in the synthesis of plastoquinone-9. Can use both homogentisic acid and 2,5-dihydroxyphenylacetic acid gamma-lactone as prenyl acceptors, and solanesyl diphosphate > farnesyl diphosphate > geranylgeranyl diphosphate >> phytyl diphosphate as prenyl donors. Do not catalyze the decardoxylation of homogentisate uncoupled from prenylation.
Similarity
Belongs to the UbiA prenyltransferase family.
Mass
39.347 kDa
Sequence
MDLCSSTGRGACLSPASTSRPCPAPVHLRGRRLAFSPAQPAGRRHLPVLSSAAVPAPLPNGGNDESFAQKLANFPNAFWKFLRPHTIRGTILGTTAVTAKVLMENPGCIDWALLPKALLGLVALLCGNGYIVGINQIYDVDIDVVNKPFLPVASGELSPALAWGLCLSLAAAGAGIVAANFGNLITSLYTFGLFLGTVYSVPPLRLKQYAVPAFMIIATVRGFLLNFGVYSATRAALGLPFEWSPAVSFITVFVTLFATVIAITKDLPDVEGDQANNISTFATRMGVRNVALLAIGLLMANYLGAIALALTYSTAFNVPLMAGAHAILAATLALRTLKLHAASYSREAVASFYRWIWNLFYAEYALLPFL

Gene
HST
Protein
Homogentisate solanesyltransferase, chloroplastic
Organism
Chlamydomonas reinhardtii
Length
370 amino acids
Function
Involved in the synthesis of plastoquinone-9. Can use both homogentisic acid and 2,5-dihydroxyphenylacetic acid gamma-lactone as prenyl acceptors, and solanesyl diphosphate > farnesyl diphosphate > geranylgeranyl diphosphate >> phytyl diphosphate as prenyl donors. Do not catalyze the decardoxylation of homogentisate uncoupled from prenylation.
Similarity
Belongs to the UbiA prenyltransferase family.
Mass
39.347 kDa
Sequence
MDLCSSTGRGACLSPASTSRPCPAPVHLRGRRLAFSPAQPAGRRHLPVLSSAAVPAPLPNGGNDESFAQKLANFPNAFWKFLRPHTIRGTILGTTAVTAKVLMENPGCIDWALLPKALLGLVALLCGNGYIVGINQIYDVDIDVVNKPFLPVASGELSPALAWGLCLSLAAAGAGIVAANFGNLITSLYTFGLFLGTVYSVPPLRLKQYAVPAFMIIATVRGFLLNFGVYSATRAALGLPFEWSPAVSFITVFVTLFATVIAITKDLPDVEGDQANNISTFATRMGVRNVALLAIGLLMANYLGAIALALTYSTAFNVPLMAGAHAILAATLALRTLKLHAASYSREAVASFYRWIWNLFYAEYALLPFL