Protein
Mitogen-activated protein kinase HOG1A
Organism
Wallemia ichthyophaga (strain EXF-994 / CBS 113033)
Function
Mitogen-activated protein kinase involved in a signal transduction pathway that is activated by changes in the osmolarity of the extracellular environment. Controls osmotic regulation of transcription of target genes.
Similarity
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. HOG1 sub-subfamily.
Sequence
MSQEDSSFVKLSVFGNIFQVTTRYTDLQPVGMGAFGLLCSSTDQKSGGPVAIKKVMKPFSAPVLAKRTYRELKLLKHLRHENIISLLDVFISPGEDIYFITELLGTDLHRLLSSRPLERQFVQYFLYQMLRALKFVHPAGVVHRDLKPSNILINENCDLKICDFGLARLQDPQMTGYVSTRYYRAPEIMLTWQEYDSAVDIWSVGCIFAEMIDGRPIFPGKDHVHQLTVITELLGSPPEDVINTITSENTRRFVDALPKRHKISFADRFPNANAEEIDLLEKMLDFNPKKRITAADALAHPYLAPYHDPEDEPTANERFDWSFNDADLPTDQWKVMMYSEILDFHNVDVKSEKDMTPSTTTAGAH