About Products Protein Database Contact

HMX3

Gene
HMX3
Protein
Homeobox protein HMX3
Organism
Homo sapiens
Length
357 amino acids
Function
Transcription factor involved in specification of neuronal cell types and which is required for inner ear and hypothalamus development. Binds to the 5'-CAAGTG-3' core sequence. Controls semicircular canal formation in the inner ear. Also required for hypothalamic/pituitary axis of the CNS (By similarity).
Similarity
Belongs to the HMX homeobox family.
Mass
37.825 kDa
Sequence
MPEPGPDAAGTASAQPQPPPPPPPAPKESPFSIKNLLNGDHHRPPPKPQPPPRTLFAPASAAAAAAAAAAAAAKGALEGAAGFALSQVGDLAFPRFEIPAQRFALPAHYLERSPAWWYPYTLTPAGGHLPRPEASEKALLRDSSPASGTDRDSPEPLLKADPDHKELDSKSPDEIILEESDSEESKKEGEAAPGAAGASVGAAAATPGAEDWKKGAESPEKKPACRKKKTRTVFSRSQVFQLESTFDMKRYLSSSERAGLAASLHLTETQVKIWFQNRRNKWKRQLAAELEAANLSHAAAQRIVRVPILYHENSAAEGAAAAAAGAPVPVSQPLLTFPHPVYYSHPVVSSVPLLRPV

Gene
Hmx3
Protein
Homeobox protein HMX3
Organism
Mus musculus
Length
356 amino acids
Function
Transcription factor involved in specification of neuronal cell types and which is required for inner ear and hypothalamus development. Binds to the 5'-CAAGTG-3' core sequence. Controls semicircular canal formation in the inner ear. Also required for hypothalamic/pituitary axis of the CNS.
Similarity
Belongs to the HMX homeobox family.
Mass
37.859 kDa
Sequence
MPEPGPDASGTASAPPPQPPPQPPAPKESPFSIRNLLNGDHHRPPPKPQPPPRTLFAPASAAAAAAAAAAAAAKGALEGAAGFALSQVGDLAFPRFEIPAQRFALPAHYLERSPAWWYPYTLTPAGGHLPRPEASEKALLRDSSPASGTDRDSPEPLLKADPDHKELDSKSPDEIILEESDSEEGKKEGEAVPGAAGTTVGATTATPGSEDWKAGAESPEKKPACRKKKTRTVFSRSQVFQLESTFDMKRYLSSSERAGLAASLHLTETQVKIWFQNRRNKWKRQLAAELEAANLSHAAAQRIVRVPILYHENSAAEGAAAAAGAPVPVSQPLLTFPHPVYYSHPVVSSVPLLRPV

Gene
HMX3
Protein
Homeobox protein HMX3
Organism
Gallus gallus
Length
308 amino acids
Function
Transcription factor involved in specification of neuronal cell types and which is required for inner ear and hypothalamus development. Binds to the 5'-CAAGTG-3' core sequence (By similarity).
Similarity
Belongs to the HMX homeobox family.
Mass
33.787 kDa
Sequence
MPETGQEPPSAPPPPPPPKESFYIKNLLNGDPPKAAPKQPRALFAPSGKADGSGFALSQVGDLSFPRFEIPAPRFALSAHCLERAQTWWYPYALTPAGAHLPRTEAAEKSLLRDSSPASGTDRDSPEPLLQGGDAEQKERDPKSPAEIVLEESDSEEGKKEGGAEDWKKREESPEKKPCRKKKTRTVFSRSQVFQLESTFDMKRYLSSSERAGLAASLHLTETQVKIWFQNRRNKWKRQLAAELEAANLSHAAAQRIVRVPILYHENSGAESSAAGGGGPGPQPLLTFPHPVYYSHPSVTSVPLLRPV

Gene
hmx3
Protein
Homeobox protein HMX3
Organism
Xenopus laevis
Length
306 amino acids
Function
Transcription factor involved in specification of neuronal cell types and which is required for inner ear and hypothalamus development. Binds to the 5'-CAAGTG-3' core sequence (By similarity). May act as a stage-specific inhibitor of anf1 in the anterior neural plate during the development.
Similarity
Belongs to the HMX homeobox family.
Mass
34.022 kDa
Sequence
MPETGQESSNPPAKESPFSIKSLLTCEPSRAARPPKALFTPIKGALDGAAFAFSPLTDFTFPRLEIPTQRFALPAHYLERSPGWWYSYTLAHGGHTPRTEVPDKSLLLGPTSPVSGGERDSPDPIHPLKTELGAKESESKSPEEIILEESDPEEGKKDDSGEDWKKREDSPDKKPCRKKKTRTVFSRSQVFQLESTFDMKRYLSSSERAGLAASLHLTETQVKIWFQNRRNKWKRQLAAELEAANLSHAAAQRIVRVPILYHENSSSAESASSAANVPVSQPLLTFPHPVYYSHPVVTSVPLLRPV

Gene
hmx3
Protein
Homeobox protein HMX3
Organism
Xenopus tropicalis
Length
306 amino acids
Function
Transcription factor involved in specification of neuronal cell types and which is required for inner ear and hypothalamus development. Binds to the 5'-CAAGTG-3' core sequence. May act as a stage-specific inhibitor of anf1 in the anterior neural plate during the development (By similarity).
Similarity
Belongs to the HMX homeobox family.
Mass
34.077 kDa
Sequence
MPETGQESSNPPAKESPFSIKSLLTCEPSRAVRPHKALFTPIKGALDGAAFALSPLTDLTFPRLEIPAQRFALPAHYLERSPAWWYSYTLAHGGHTPRTEVPDKSLLLGPTSPVSGGERDSPEPIHPLKAELEAKDSESKSPEEIILEESEPEEGKKDDSGEDWKKREESPDKKPCRKKKTRTVFSRSQVFQLESTFDMKRYLSSSERAGLAASLHLTETQVKIWFQNRRNKWKRQLAAELEAANLSHAAAQRIVRVPILYHENSSSAESASSAANVPVSQPLLTFPHPVYYSHPVVTSVPLLRPV

Gene
hmx3
Protein
Homeobox protein HMX3
Organism
Danio rerio
Length
297 amino acids
Function
Transcription factor involved in specification of neuronal cell types and which is required for inner ear and hypothalamus development. Binds to the 5'-CAAGTG-3' core sequence (By similarity).
Similarity
Belongs to the HMX homeobox family.
Mass
33.088 kDa
Sequence
MPETTQDTCASAKDSPFFIKNLLNSDSKPSKPKPILAPTKAGLDGSFSLSQVGEINFPRFELPTQRFALPAYLERASAWWYPYTLSASAHLHRTEAAQKARDSSPTTGTDRDSPELVLKSDPDAKDDEDDNKSGDEIVLEEGDTEDGKKEGGIDDWKKSDDGADKKPCRKKKTRTVFSRSQVFQLESTFDMKRYLSSSERAGLAASLHLTETQVKIWFQNRRNKWKRQLAAELEAANLSHAAAQRIVRVPILYHENSASESTNTAGNVPVSQPLLTFPHPVYYSHPIVTSVPLLRPV