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HMX1

Gene
HMX1
Protein
Homeobox protein HMX1
Organism
Homo sapiens
Length
348 amino acids
Function
DNA-binding protein that binds to the 5'-CAAG-3' core sequence. May function as a transcriptional repressor. Seems to act as a transcriptional antagonist of NKX2-5. May play an important role in the development of craniofacial structures such as the eye and ear.
Similarity
Belongs to the HMX homeobox family.
Mass
36.155 kDa
Sequence
MPDELTEPGRATPARASSFLIENLLAAEAKGAGRATQGDGSREDEEEDDDDPEDEDAEQARRRRLQRRRQLLAGTGPGGEARARALLGPGALGLGPRPPPGPGPPFALGCGGAARWYPRAHGGYGGGLSPDTSDRDSPETGEEMGRAEGAWPRGPGPGAVQREAAELAARGPAAGTEEASELAEVPAAAGETRGGVGVGGGRKKKTRTVFSRSQVFQLESTFDLKRYLSSAERAGLAASLQLTETQVKIWFQNRRNKWKRQLAAELEAASLSPPGAQRLVRVPVLYHESPPAAAAAGPPATLPFPLAPAAPAPPPPLLGFSGALAYPLAAFPAAASVPFLRAQMPGLV
Protein
Homeobox protein HMX1: HMX1

Gene
HMX1
Protein
Homeobox protein HMX1
Organism
Gallus gallus
Length
333 amino acids
Function
DNA-binding protein that binds to the 5'-CAAG-3' core sequence. May function as a transcriptional repressor. Seems to act as a transcriptional antagonist of NKX2-5. May play an important role in the development of craniofacial structures such as the eye and ear.
Similarity
Belongs to the HMX homeobox family.
Mass
34.897 kDa
Sequence
MAQDRECLCSAGFQRGDYTQGNTDRSTAAANSRPPAGQRGAEEPSSGGAGTPPPAAVLPTMPDEATENAGSTSARVSSFFIEDLLGTEGGGGTRRAAAGGGGGRGAPRCGPHSPLRLGASGCPLRDAAVGWYRRAFLGCASPDTSDRDSPELPEDTERAGGGGRAAARGPAGGRQSSGGREEEEERGEEAGEAEQRAAGRKKKTRTVFSRSQVFQLESTFDVKRYLSSSERAGLAASLHLTETQVKIWFQNRRNKWKRQLAADLEAANLSHAAQRIVRVPILYHENSPASALGFGLPHMSPPLVGFSGGVSYPLGTFPAASLPFLRSQMTGLV
Protein
Homeobox protein HMX1: HMX1

Gene
Hmx1
Protein
Homeobox protein HMX1
Organism
Mus musculus
Length
332 amino acids
Function
DNA-binding protein that binds to the 5'-CAAG-3' core sequence. May function as a transcriptional repressor. Seems to act as a transcriptional antagonist of NKX2-5. May play an important role in the development of craniofacial structures such as the eye and ear.
Similarity
Belongs to the HMX homeobox family.
Mass
35.054 kDa
Sequence
MPDELTEPGRATPARASSFLIENLLAAEAKGAGRSTQGDGVREEEEEDDDDPEDEDPEQARRRLQRRRQQRAGSGPGGEARARALGLGPRPPPGPGPPFALGCGGTTRWYPRVHGGYGGGLSPDTSDRDSPETGEEMGRAESAWPRCPGPGTVPREVTTQGPATGGEEAAELAEAPAVAAAATGEARGGRRKKTRTVFSRSQVFQLESTFDLKRYLSSAERAGLAASLQLTETQVKIWFQNRRNKWKRQLAAELEAASLSPPGAQRLVRVPVLYHESPPAAAGPALPFPLAPPAPAPPPPLLGFSGALAYPLAAFPAAASVPFLRAQMPGLV
Protein
Homeobox protein HMX1: Hmx1

Gene
HMX1
Protein
Heme-binding protein HMX1
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Length
317 amino acids
Function
Plays an important role in the degradation of heme under conditions of iron deprivation.
Mass
37.179 kDa
Sequence
MEDSSNTIIPSPTDVGALANRINFQTRDAHNKINTFMGIKMAIAMRHGFIYRQGILAYYYVFDAIEQEIDRLLNDPVTEEELQTSTILKQFWLEDFRRSTQIYKDLKLLYSNTFKSTESLNEFLATFQKPPLLQQFINNIHENIHKEPCTILSYCHVLYLALFAGGKLIRSNLYRRLGLFPNFEKLSQKELVKKGTNFFTFSDLGPTEETRLKWEYKKNYELATRTELTEAQKLQIISVAEGIFDWNFNIVAEIGELNRRELMGKFSFKCITYLYEEWMFNKDSATRRALHTVMLLVLSIIAIWVLYFLVKSFLSIV
Protein
Heme-binding protein HMX1: HMX1