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HINFP

Gene
HINFP
Protein
Histone H4 transcription factor
Organism
Homo sapiens
Length
517 amino acids
Function
Transcriptional repressor that binds to the consensus sequence 5'-CGGACGTT-3' and to the RB1 promoter. Transcriptional activator that promotes histone H4 gene transcription at the G1/S phase transition in conjunction with NPAT. Also activates transcription of the ATM and PRKDC genes. Autoregulates its expression by associating with its own promoter.
Mass
59.678 kDa
Sequence
MPPPGKVPRKENLWLQCEWGSCSFVCSTMEKFFEHVTQHLQQHLHGSGEEEEEEEEDDPLEEEFSCLWQECGFCSLDSSADLIRHVYFHCYHTKLKQWGLQALQSQADLGPCILDFQSRNVIPDIPDHFLCLWEHCENSFDNPEWFYRHVEAHSLCCEYEAVGKDNPVVLCGWKGCTCTFKDRSKLREHLRSHTQEKVVACPTCGGMFANNTKFLDHIRRQTSLDQQHFQCSHCSKRFATERLLRDHMRNHVNHYKCPLCDMTCPLPSSLRNHMRFRHSEDRPFKCDCCDYSCKNLIDLQKHLDTHSEEPAYRCDFENCTFSARSLCSIKSHYRKVHEGDSEPRYKCHVCDKCFTRGNNLTVHLRKKHQFKWPSGHPRFRYKEHEDGYMRLQLVRYESVELTQQLLRQPQEGSGLGTSLNESSLQGIILETVPGEPGRKEEEEEGKGSEGTALSASQDNPSSVIHVVNQTNAQGQQEIVYYVLSEAPGEPPPAPEPPSGGIMEKLQGIAEEPEIQMV

Gene
HINFP
Protein
Histone H4 transcription factor
Organism
Bos taurus
Length
516 amino acids
Function
Transcriptional repressor that binds to the consensus sequence 5'-CGGACGTT-3' and to the RB1 promoter. Transcriptional activator that promotes histone H4 gene transcription at the G1/S phase transition in conjunction with NPAT. Also activates transcription of the ATM and PRKDC genes. Autoregulates its expression by associating with its own promoter (By similarity).
Mass
59.256 kDa
Sequence
MPPPGKVPRKENLGLQCEWGSCSFVCSAMEEFCEHVTQHLQQHLQGSGEEEEEEEDLLEEEFSCLWRECGFCSPDNSADLIRHVYFHCYHTKLKQWGLQALQSQADLSPCILDFQSRNLIPDIPDHFLCLWEHCENSFDNPEWFYRHVEAHSQCCEYQVVGKDNNVVLCGWKGCTCTFKDRFKLREHLRSHTQEKVVACPTCGGMFANNTKFLDHIRRQSSLDQQHFQCSHCSKRFATERLLRDHMRNHVNHYKCPLCDMTCPLPSSLRNHMRFRHSEARPFKCDCCDYSCKNLIDLRKHLDTHSKEPAYSCDFENCTFSARSLYSIKSHYRKVHEGDSEPRYRCHVCDKCFTRGNNLTVHLRKKHQFKWPSGHPRFRYKEHEDGYMRLQLVRYESVELTQQLLRQPQEGSGLGASLNESSLQDIILETVPGEPGPQEEAEEEGGGGEGIALPASQGTSSPIIHVVNQTNAQGEREVVYYVLFEAPGEPPPASEPPSGGVMGELQGAAEEPEVQMV

Gene
Hinfp
Protein
Histone H4 transcription factor
Organism
Mus musculus
Length
503 amino acids
Function
Transcriptional repressor that binds to the consensus sequence 5'-CGGACGTT-3' and to the RB1 promoter. Transcriptional activator that promotes histone H4 gene transcription at the G1/S phase transition in conjunction with NPAT. Also activates transcription of the ATM and PRKDC genes. Autoregulates its expression by associating with its own promoter.
Mass
58.076 kDa
Sequence
MSPPGKVPRKENLGLQCEWGSCSFVCSAMEEFFDHVTQHLQQHMHGSKEEEEEDPLEEEFSCLWQECGFCSLDSSADLIRHVYFHCYHTKLKQWGLQALQSQADLSPCILDFQSRNVIPDTPDHFLCLWEHCESVFDNPEWFYRHVDAHSLCCEYQAVSKDNHVVQCGWKGCTCTFKDRCKLREHLRSHTQEKVVACPTCGGMFANNTKFLDHIRRQTSLDQQRFQCSHCSKRFATERLLRDHMRNHVNHYKCPLCDMTCPLPSSLRNHMRFRHSEDRPYKCDCCDYSCKNLIDLRKHLDTHSKESAYRCDFENCNFSARSLSSVKSHHRKVHEGDSEPRYKCHVCDKCFTRGNNLTVHLRKKHQFKWPSGHPRFRYKEHEDGYMRLQLVRYESVELTQQLLQQLQEGSDPGLALNESSLQGIVLETVLGGPGPEEETEEEGRVVEGTALSASQDNPSSAIHMVSQTDTQGQRDIVYCVLSEGPGEPPPVSETLKRDGKARGT