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HGPRT

Gene
HGPRT
Protein
Hypoxanthine-guanine phosphoribosyltransferase
Organism
Schistosoma mansoni
Length
284 amino acids
Function
Converts guanine to guanosine monophosphate, and hypoxanthine to inosine monophosphate. Transfers the 5-phosphoribosyl group from 5-phosphoribosylpyrophosphate onto the purine. Plays a central role in the generation of purine nucleotides through the purine salvage pathway (By similarity).
Similarity
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
Mass
31.854 kDa
Sequence
MLTSLITSSTTVTLTLSQIYYILDIACGFLISVLVWMNSSVLDNGNHSNPQIRDMSSNMIKADCVVIEDSFRGFPTEYFCTSPRYDECLDYVLIPNGMIKDRLEKMSMDIVDYYEACNATSITLMCVLKGGFKFLADLVDGLERTVRARGIVLPMSVEFVRVKSYVNDVSIHEPILTGLGDPSEYKDKNVLVVEDIIDTGKTITKLISHLDSLSTKSVKVASLLVKRTSPRNDYRPDVGFEVPNRFVVGYALDYNDNFRDLHHICVINEVGQKKFSVPCTSKPV

Gene
HGPRT
Protein
Hypoxanthine-guanine phosphoribosyltransferase
Organism
Trypanosoma brucei brucei
Length
210 amino acids
Function
Converts guanine to guanosine monophosphate, and hypoxanthine to inosine monophosphate. Transfers the 5-phosphoribosyl group from 5-phosphoribosylpyrophosphate onto the purine. Plays a central role in the generation of purine nucleotides through the purine salvage pathway (By similarity).
Similarity
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
Mass
23.36 kDa
Sequence
MEPACKYDFATSVLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVIVSVLKGSFVFTADMVRILGDFGVPTRVEFLRASSYGHDTKSCGRVDVKADGLCDIRGKHVLVLEDILDTALTLREVVDSLKKSEPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYREVRDVVILKPSVYETWGKELERRKAAGEAKR

Gene
HGPRT
Protein
Hypoxanthine-guanine phosphoribosyltransferase
Organism
Crithidia fasciculata
Length
208 amino acids
Function
Converts guanine to guanosine monophosphate, and hypoxanthine to inosine monophosphate. Transfers the 5-phosphoribosyl group from 5-phosphoribosylpyrophosphate onto the purine. Plays a central role in the generation of purine nucleotides through the purine salvage pathway (By similarity).
Similarity
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
Mass
23.323 kDa
Sequence
MSNAASPATSAAPVRHYPMSCRTLATQEQIWSATAKCAKQIAEDYKQYNLSDENPLYLLCVLKGSFMFTADLARFLCDEGVPVRIEFICASSYGTDVKTSGEVRLLLDVRDPVENRHLLIVEDIVDSAITLEYLKRFLQAKQPASLKTVVLLDKPSGRKVTLSVDYPVITIPHAFVIGYGMDFAEAYRELRDVCVLKKEYYEKPASKL