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HAND1

Gene
HAND1
Protein
Heart- and neural crest derivatives-expressed protein 1
Organism
Bos taurus
Length
218 amino acids
Function
Transcription factor that plays an essential role in both trophoblast-giant cells differentiation and in cardiac morphogenesis. In the adult, could be required for ongoing expression of cardiac-specific genes. Binds the DNA sequence 5'-NRTCTG-3' (non-canonical E-box) (By similarity).
Mass
23.966 kDa
Sequence
MNLVGSYAHHHHHHHHHHPHPAHPMLHEPFLFGPASRCHQERPYFQSWLLSPADAAPDFPAGGPPPAAAAAAASYGPDARPGQSPGRLEALGGRLGRRKGSGPKKERRRTESINSAFAELRECIPNVPADTKLSKIKTLRLATSYIAYLMDVLAKDAQAGDPEAFKAELKKADGGRESKRKRELQQHEGFPPALGPGEKRIKGRTGWPQQVWALELNQ

Gene
Hand1
Protein
Heart- and neural crest derivatives-expressed protein 1
Organism
Mus musculus
Length
216 amino acids
Function
Transcription factor that plays an essential role in both trophoblast-giant cells differentiation and in cardiac morphogenesis. In the adult, could be required for ongoing expression of cardiac-specific genes. Binds the DNA sequence 5'-NRTCTG-3' (non-canonical E-box).
Mass
23.806 kDa
Sequence
MNLVGSYAHHHHHHHSHPPHPMLHEPFLFGPASRCHQERPYFQSWLLSPADAAPDFPAGGPPPTTAVAAAAYGPDARPSQSPGRLEALGSRLPKRKGSGPKKERRRTESINSAFAELRECIPNVPADTKLSKIKTLRLATSYIAYLMDVLAKDAQAGDPEAFKAELKKTDGGRESKRKRELPQQPESFPPASGPGEKRIKGRTGWPQQVWALELNQ

Gene
Hand1
Protein
Heart- and neural crest derivatives-expressed protein 1
Organism
Rattus norvegicus
Length
216 amino acids
Function
Transcription factor that plays an essential role in both trophoblast-giant cells differentiation and in cardiac morphogenesis. In the adult, could be required for ongoing expression of cardiac-specific genes. Binds the DNA sequence 5'-NRTCTG-3' (non-canonical E-box) (By similarity).
Mass
23.81 kDa
Sequence
MNLVGSYAHHHHHHHSHPPHPMLHEPFLFGPASRCHQERPYFQSWLLSPADAAPDFPAGGPPPTTAVAAAAYGPDARPSQSPGRLEALGGRLPRRKGSGPKKERRRTESINSAFAELRECIPNVPADTKLSKIKTLRLATSYIAYLMDVLAKDAQAGDPEAFKAELKKTDGGRESKRKRESPQQHEGLPPALGPSEKRIKGRTGWPQQVWALELNQ

Gene
HAND1
Protein
Heart- and neural crest derivatives-expressed protein 1
Organism
Homo sapiens
Length
215 amino acids
Function
Transcription factor that plays an essential role in both trophoblast-giant cells differentiation and in cardiac morphogenesis. In the adult, could be required for ongoing expression of cardiac-specific genes. Binds the DNA sequence 5'-NRTCTG-3' (non-canonical E-box) (By similarity).
Mass
23.627 kDa
Sequence
MNLVGSYAHHHHHHHPHPAHPMLHEPFLFGPASRCHQERPYFQSWLLSPADAAPDFPAGGPPPAAAAAATAYGPDARPGQSPGRLEALGGRLGRRKGSGPKKERRRTESINSAFAELRECIPNVPADTKLSKIKTLRLATSYIAYLMDVLAKDAQSGDPEAFKAELKKADGGRESKRKRELQQHEGFPPALGPVEKRIKGRTGWPQQVWALELNQ

Gene
HAND1
Protein
Heart- and neural crest derivatives-expressed protein 1
Organism
Oryctolagus cuniculus
Length
215 amino acids
Function
Transcription factor that plays an essential role in both trophoblast-giant cells differentiation and in cardiac morphogenesis. In the adult, could be required for ongoing expression of cardiac-specific genes. Binds the DNA sequence 5'-NRTCTG-3' (non-canonical E-box) (By similarity).
Mass
23.687 kDa
Sequence
MNLVGSYAHHHHHHHPHPAHPMLHEPFLFGPASRCHQERPYFQSWLLSPADAAPDFPTGGPPPTAAAAAATYGPDTRPGQSPGRLEALGGRLGRRKGSGPKKERRRTESINSAFAELRECIPNVPADTKLSKIKTLRLATSYIAYLMDVLAKDAQAGDPEAFKAELKKVDGGRESKRKRELQQHEGFPPALGPGEKRIKGRTGWPQQVWALELNQ

Gene
HAND1
Protein
Heart- and neural crest derivatives-expressed protein 1
Organism
Ovis aries
Length
204 amino acids
Function
Transcription factor that plays an essential role in both trophoblast-giant cells differentiation and in cardiac morphogenesis. In the adult, could be required for ongoing expression of cardiac-specific genes. Binds the DNA sequence 5'-NRTCTG-3' (non-canonical E-box) (By similarity).
Mass
22.427 kDa
Sequence
MNLVGSYAHHHHHHHHHHHPHPAHPMLHEPFLFGPASRCHQERPYFQSWLLSPADAAPDFPAGGPPPTTAVRAAAASYGPDARPGQSPGRLEALGGRLGRRKGSGPKKERRRTESINSAFAELRECIPNVPADTKLSKIKTLRLATSYIAYLMDVLAKDAQAGDPEAFKAELKKADGGRESKRKRELQQHEGFPPALGPGEKRD

Gene
HAND1
Protein
Heart- and neural crest derivatives-expressed protein 1
Organism
Gallus gallus
Length
202 amino acids
Function
Plays an essential role in cardiac morphogenesis.
Mass
22.679 kDa
Sequence
MNLVGGYQHHHHHHHHHHMLHEPFLFGPAARCHQERAYFPGWVLNPAEVTPELHGQSPAYGPAEFGSGGAGRLEALSGRLGRRKGVGGPKKERRRTESINSAFAELRECIPNVPADTKLSKIKTLRLATSYIAYLMEVLARDSQPGEPEGFKAELKKADGRENKRKRETQPEVYSQPLAHGEKKLKGRTGWPQQVWALELNP

Gene
hand1
Protein
Heart- and neural crest derivatives-expressed protein 1
Organism
Xenopus laevis
Length
197 amino acids
Function
Plays an essential role in cardiac morphogenesis.
Mass
22.001 kDa
Sequence
MNLIGSYQHHHHHMMPDPFIFSPGSRCHQERPYFQGWVLNPGEVSPEFPAQPPYSPEYGAVVGPSQTSGRIENLGGKLGRRKGAPPKKERRRTESINSAFAELRECIPNVPADTKLSKIKTLRLATSYIGYLMDVLAKDSEPGGTEAFKAEIKKVDGKRRREPQPTEGYWGAAPAGEKKLKGRTGWPQQVWALELNP