HAM2

Gene

HAM2

Protein

Histone acetyltransferase of the MYST family 2

Organism

Arabidopsis thaliana

Length

445 amino acids

Function

Histone acetyltransferase which may be involved in transcriptional activation. Acetylates 'Lys-5' of histone H4 (H4K5ac) (PubMed:16648464, PubMed:17877703). Essential for gametophyte development (PubMed:19040736). Negative regulator of flowering controlling the H4K5ac levels in the FLC chromatin (PubMed:23273925).

Similarity

Belongs to the MYST (SAS/MOZ) family.

Mass

51.367 kDa

Sequence

MGSSANTETNGNAPPPSSNQKPPATNGVDGSHPPPPPLTPDQAIIESDPSKKRKMGMLPLEVGTRVMCRWRDGKHHPVKVIERRRIHNGGQNDYEYYVHYTEFNRRLDEWTQLDQLDLDSVECAVDEKVEDKVTSLKMTRHQKRKIDETHIEGHEELDAASLREHEEFTKVKNISTIELGKYEIETWYFSPFPPEYNDCVKLFFCEFCLNFMKRKEQLQRHMRKCDLKHPPGDEIYRSGTLSMFEVDGKKNKVYAQNLCYLAKLFLDHKTLYYDVDLFLFYVLCECDDRGCHMVGYFSKEKHSEEAYNLACILTLPSYQRKGYGKFLIAFSYELSKKEGKVGTPERPLSDLGLLSYRGYWTRVLLEILKKHKGNISIKELSDVTAIKAEDILSTLQSLELIQYRKGQHVICADPKVLDRHLKAAGRGGLDVDASKLIWTPYKDQS

Protein

Histone acetyltransferase of the MYST family 2: HAM2