HAC1

Histone acetyltransferase HAC1

1697 amino acids

Acetyltransferase enzyme. Acetylates histones, giving a specific tag for transcriptional activation.

190.045 kDa

MNVQAHMSGQVSNQGTMSQQNGNSQMQNLVGGGSAPATGAGLGPSRVSPVDNDILKLRQAMRIRIFNILQQKQPSPADEASKAKYMDVARRLEEGLFKIANTKEDYVNPSTLEPRLASLIKGRQLNNYNQRHANSSSVGTMIPTPGLQHSGGNPNLMITSSGDATMAGSNNITTSAMNTGNLLNSGGMLGGNLSNGYQHSSSNFGLGSGGNMSSMSSQRNTGQMMPTPGFVNSSTNNNSNNGQSYLSVEASNNSGGFSTAPMMVPQTQQQQLRQDIGGQNSRMLQNHGSQMGVGLRPGMQQKLSNVSNSSINGGVGMNAKSVDSGTSYTNPIRNSQQAYDNLQRSGMQGDGYGTNNSDPFGSGNLYGAVTSVGMMTNTQNANTASFQAVSRTSSSLSHQQQQFQQQPNRFQQQPNQFHQQQQQFLHQQQLKQQSQQQQRFISHDAFGQNNVASDMVTHVKHEPGMENPSESIHSQTPEQFQLSQFQNQYQNNAEDRHAGSQILPVTSQSDMCTSVPQNSQQIQQMLHPHSMASDSVNGFSNLSVGVKTESGMRGHWQSQSQEHTQMSNSMSNERHIQEDFRQRMSGTDEAQPNNMSGGSIIGQNRVSTTSESLNPQNPTATTCRNGNGNRDPRFKNQQKWLLFLRHARHCKAPEGKCPDRNCVTVQKLWKHMDSCAAPQCSYPRCLPTKTLINHHRSCKEPNCPVCIPVKAYLQQQANARSLARLKNETDAARSVNGGGISSDAVQTSAGAKSCTSPGADISGHLQPSLKRLKVEQSSQPVDVETESCKSSVVSVTEAQSSQYAERKDHKHSDVRAPSKYFEVKAEVSDFSVQTRPGFKDTKIGIAENIPKQRPVSQPDKQDLSDVSPMQETTKVEKEPESLKKENLAESTEHTSKSGKPEIKGVSLTELFTPEQVREHIRGLRQWVGQSKAKAEKNQAMEHSMSENSCQLCAVEKLTFEPPPIYCTPCGARIKRNAMYYTVGAGDTRHYFCIPCYNESRGDTILAEGTPMPKARLEKKKNDEETEEWWVQCDKCEAWQHQICALFNGRRNDGGQAEYTCPYCFIAEVEQSKRKPLPQSAVLGAKDLPRTILSDHIEQRLFKRLKQERTERARAQGKSYDEIPTAESLVIRVVSSVDKKLEVKPRFLEIFREDSYPTEFAYKSKVVLLFQKIEGVEVCLFGMYVQEFGSECAFPNQRRVYLSYLDSVKYFRPEVRSYNGEALRTFVYHEILIGYLEYCKLRGFTSCYIWACPPLKGEDYILYCHPEIQKTPKSDKLREWYLAMLRKASKEGIVAETINLYDHFFMQTGECRAKVTAARLPYFDGDYWPGAAEDLIYQMSQEEDGRKGNKKGMLKKTITKRALKASGQTDLSGNASKDLLLMHRLGETIHPMKEDFIMVHLQPSCTHCCILMVSGNRWVCSQCKHFQICDKCYEAEQRREDRERHPVNFKDKHALYPVEIMDIPADTRDKDEILESEFFDTRQAFLSLCQGNHYQYDTLRRAKHSSMMVLYHLHNPTAPAFVTTCNACHLDIETGQGWRCEVCPDYDVCNACFSRDGGVNHPHKLTNHPSLADQNAQNKEARQLRVLQLRKMLDLLVHASQCRSAHCQYPNCRKVKGLFRHGINCKVRASGGCVLCKKMWYLLQLHARACKESECHVPRCRDLKEHLRRLQQQSDSRRRAAVMEMMRQRAAEVAGGSG

hac1

Transcriptional activator hac1

451 amino acids

Transcriptional activator involved in the unfolded protein response (UPR) pathway. Recognizes and binds to the UPR element (UPRE) in the promoter of UPR-regulated genes. Increases the synthesis of endoplasmic reticulum-resident proteins required for protein folding as well as components of the secretory pathway (By similarity).

Belongs to the bZIP family.

49.278 kDa

MAFQQSSPLVKFEASPAESFLSAPGDNFTSLFADSTPSTLNPRDMMTPDSVADIDSRLSVIPESQDAEDDESHSTSATAPSTSEKKPVKKRKSWGQVLPEPKTNLPPRKRAKTEDEKEQRRVERVLRNRRAAQSSRERKRLEVEALEKRNKELETLLINVQKTNLILVEELNRFRRSSGVVTRSSSPLDSLQDSITLSQQLFGSRDGQTMSNPEQSLMDQIMRSAANPTVNPASLSPSLPPISDKEFQTKEEDEEQADEDEEMEQTWHETKEAAAAKEKNSKQSRVSTDSTQRPAVSIGGDAAVPVFSDDAGANCLGLDPVHQDDGPFSIGHSFGLSAALDADRYLLESQLLASPNASTVDDDYLAGDSAACFTNPLPSDYDFDINDFLTDDANHAAYDIVAASNYAAADRELDLEIHDPENQIPSRHSIQQPQSGASSHGCDDGGIAVGV

HAC1

Transcriptional activator HAC1

238 amino acids

Transcriptional activator involved in the unfolded protein response (UPR) pathway. Recognizes and binds to the UPR element (UPRE) in the promoter of UPR-regulated genes such as KAR2, PDI1, EUG1 and FKB2. Increases the synthesis of endoplasmic reticulum-resident proteins required for protein folding as well as components of the secretory pathway.

Belongs to the bZIP family.

26.905 kDa

MEMTDFELTSNSQSNLAIPTNFKSTLPPRKRAKTKEEKEQRRIERILRNRRAAHQSREKKRLHLQYLERKCSLLENLLNSVNLEKLADHEDALTCSHDAFVASLDEYRDFQSTRGASLDTRASSHSSSDTFTPSPLNCTMEPATLSPKSMRDSASDQETSWELQMFKTENVPESTTLPAVDNNNLFDAVASPLADPLCDDIAGNSLPFDNSIDLDNWRNPEAQSGLNSFELNDFFITS