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H3-5

Gene
H3-5
Protein
Histone H3-5
Organism
Stylonychia lemnae
Length
114 amino acids
Function
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Similarity
Belongs to the histone H3 family.
Mass
12.885 kDa
Fragment
single
Sequence
NTGAKAPRKQLANKAARKSTNVNAVSGVKKPHRFRPGTVALREIRRFQKSTELLIRKLPFQRLVREIAQEYKSDLRFQSQAVLALQEAAEAYLVGLFEDTNLCAIHAKRVTIMP