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Gr68a

Gene
Gr68a
Protein
Gustatory receptor 68a
Organism
Drosophila melanogaster
Length
389 amino acids
Function
Dsx-dependent essential component of pheromone-driven courtship behavior (PubMed:12971900). Recognizes a female pheromone involved in the second step (tapping step) of the courtship display which is essential for efficient execution of the entire courtship sequence and timely mating (PubMed:12971900). Required for detection of the male sex pheromone CH503 which is transferred from males to females during mating and inhibits courtship behavior by other males (PubMed:26083710). Gr68a-expressing neurons in the male foreleg relay signals to the suboesophageal zone (SEZ) and courtship suppression is mediated by the release of the neuropeptide tachykinin from a cluster of 8-10 neurons in the SEZ (PubMed:26083710).
Similarity
Belongs to the insect chemoreceptor superfamily. Gustatory receptor (GR) family. Gr21a subfamily.
Mass
43.78 kDa
Sequence
MKIYQDIYPISKPSQIFAILPFYSGDVDDGFRFGGLGRWYGRLVALIILIGSLTLGEDVLFASKEYRLVASAQGDTEEINRTIETLLCIISYTMVVLSSVQNASRHFRTLHDIAKIDEYLLANGFRETYSCRNLTILVTSAAGGVLAVAFYYIHYRSGIGAKRQIILLLIYFLQLLYSTLLALYLRTLMMNLAQRIGFLNQKLDTFNLQDCGHMENWRELSNLIEVLCKFRYITENINCVAGVSLLFYFGFSFYTVTNQSYLAFATLTAGSLSSKTEVADTIGLSCIWVLAETITMIVICSACDGLASEVNGTAQILARIYGKSKQFQNLIDKFLTKSIKQDLQFTAYGFFSIDNSTLFKIFSAVTTYLVILIQFKQLEDSKVEDISQA