Gramd4

GRAM domain-containing protein 4

633 amino acids

Plays a role as a mediator of E2F1-induced apoptosis in the absence of p53/TP53 (By similarity). Inhibits TLR9 response to nucelic acids and regulates TLR9-mediated innate immune response (PubMed:25917084).

72.264 kDa

MGIASHSAFRERESSPTGASLDASPRPWDKGLSGREPPRHVQVRPRSAVLNMLRRLDRIRFRGHKREDLLDLAESPNASDTECGDEIPLKTPRPSPRDSEELRDPAGPGTLIMAAGVQDFNRTEFDRLNEIKGHLEIALLEKHFLQEELRKLREETNSEMLRQELDRERQRRIELEQKMQEVLKARSEEQPAQPQQPPKGQSQASNGTGTERRSQGLASRVQKWFYERFGEYIEDFRFQPEENTVETEEPLSARRLTENMRRLKRGAKPVTNFVKNLSALSDWYSIYTSAIAFTVYMNAVWHGWAIPMFLFLAILRLSLNYLIARGWRIQWSIVPEVSEAVEPAKEDLTVSEKFQLVLDVAQKAQNLFGKMADILEKIKNLFMWVQPETTQKLYVALWAAFLASCFFPYRLVGLAVGLYAGIKFFLIDFIFKRCPRLRAKYDTPYIIWRSLPTDPQLKERAGATVSRRLQTASSRSYVSSAPAGLSKDEDAGRFHSTKKGNFHEIFNLTENERPLAVCENGWRCCLINRDRKMPTDYIRNGVLYVTENYLCFESSKSGSSKRNKVIKLMDITDIQKYKVLSVLPGSGMGIAVSTPSTQKPLVFGAMVHRDEAFETIFSQYVKITSAAASGGDS

GRAMD4

GRAM domain-containing protein 4

578 amino acids

Plays a role as a mediator of E2F1-induced apoptosis in the absence of p53/TP53 (PubMed:15565177). Plays a role as a mediator of E2F1-induced apoptosis in the absence of p53/TP53. Inhibits TLR9 response to nucelic acids and regulates TLR9-mediated innate immune response (By similarity).

66.408 kDa

MLRRLDKIRFRGHKRDDFLDLAESPNASDTECSDEIPLKVPRTSPRDSEELRDPAGPGTLIMATGVQDFNRTEFDRLNEIKGHLEIALLEKHFLQEELRKLREETNAEMLRQELDRERQRRMELEQKVQEVLKARTEEQMAQQPPKGQAQASNGAERRSQGLSSRLQKWFYERFGEYVEDFRFQPEENTVETEEPLSARRLTENMRRLKRGAKPVTNFVKNLSALSDWYSVYTSAIAFTVYMNAVWHGWAIPLFLFLAILRLSLNYLIARGWRIQWSIVPEVSEPVEPPKEDLTVSEKFQLVLDVAQKAQNLFGKMADILEKIKNLFMWVQPEITQKLYVALWAAFLASCFFPYRLVGLAVGLYAGIKFFLIDFIFKRCPRLRAKYDTPYIIWRSLPTDPQLKERSSAAVSRRLQTTSSRSYVPSAPAGLGKEEDAGRFHSTKKGNFHEIFNLTENERPLAVCENGWRCCLINRDRKMPTDYIRNGVLYVTENYLCFESSKSGSSKRNKVIKLVDITDIQKYKVLSVLPGSGMGIAVSTPSTQKPLVFGAMVHRDEAFETILSQYIKITSAAASGGDS

gramd4

GRAM domain-containing protein 4

578 amino acids

Plays a role as a mediator of e2f1-induced apoptosis in the absence of p53/TP53.

66.546 kDa

MLKRLDKIRFRGQKRDDFLDLVESPNASDTECGDEIPMKIPPTSLKDTEELKDPAGSGTIIMASGVAEYNRTESDRLNEVKGHLEIALLEKHFLQEELRKLREETNIDTLKQELEKERQRRTELEQKITDIAKTRTDESATQQLSKGPSQTNGADKQRSKTMCYRVQKWFYDKFGEYIEDFRFQPEECTVETEEPLSARRLTENMRRLKRGAKPVTNFVKNLSALSDWHSVYTSAIAFIIYMNAVWHGWAIPMFLFLAILRLSLNYLIARGWRIQWSIVPQVSETLELPKEDLTVSEKFQLVLDVAQKAQNLFGKMADILEKIKNLFMWVQPEMTQKLYIGLWAAFVASCFFHYKTIGLCMGLYAGIKFFLIDFIFKRCPRLRAKYDTPYIIWTSLPTDPQLKERTNATSSRRIQTVYSRGNLASSAPQGVSRDEETGRFHSTKKSSFHEIFSLLETERPLPACETGWRCCLINRDRKMPTDYIRNGILYVTENFLCFESSRSGSSKRNKVIKLTDITDIQKYKVLSVLPGSGMGIAVSTPSTQKPLVFGAMVHRDEAFETIFSQYVKITSAVTNSDT