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GPX1

Gene
GPX1
Protein
Phospholipid hydroperoxide glutathione peroxidase 1, chloroplastic
Organism
Arabidopsis thaliana
Length
236 amino acids
Function
Protects cells and enzymes from oxidative damage, by catalyzing the reduction of hydrogen peroxide, lipid peroxides and organic hydroperoxide, by glutathione.
Similarity
Belongs to the glutathione peroxidase family.
Mass
26.016 kDa
Sequence
MVSMTTSSSSYGTFSTVVNSSRPNSSATFLVPSLKFSTGISNFANLSNGFSLKSPINPGFLFKSRPFTVQARAAAEKTVHDFTVKDIDGKDVALNKFKGKVMLIVNVASRCGLTSSNYSELSHLYEKYKTQGFEILAFPCNQFGFQEPGSNSEIKQFACTRFKAEFPIFDKVDVNGPSTAPIYEFLKSNAGGFLGGLIKWNFEKFLIDKKGKVVERYPPTTSPFQIEKDIQKLLAA

Gene
GPX1
Protein
Glutathione peroxidase
Organism
Molluscum contagiosum virus subtype 1
Length
220 amino acids
Function
May protect the virus and component of infected cells from oxidative damage by peroxides whose formation may be stimulated by infection.
Similarity
Belongs to the glutathione peroxidase family.
Mass
24.218 kDa
Sequence
MADGSGARFPRFSELCAKYAAQLAAAETRSVYAFSARPITGGEPVSLGFLRGRVLLIENVASLUGSTVREYTQMNELQRRLGARGLVVLGFPCNQFGHQENAQNAEILPSLKHVRPGNGFEPNFMLFEKCEVNGARAHPLFAFLREALPAPSDDMSTLVSDPQLIAWSPVCRNDVAWNFEKFLVGADGTPVRRYSHRCQTLAVEPDIEALLPPPARGYYA

Gene
GPX1
Protein
Glutathione peroxidase 1
Organism
Sus scrofa
Length
206 amino acids
Function
Protects the hemoglobin in erythrocytes from oxidative breakdown.
Similarity
Belongs to the glutathione peroxidase family.
Mass
22.591 kDa
Sequence
MCAAQRSAAALAAVAPRSVYAFSARPLAGGEPISLGSLRGKVLLIENVASLUGTTVRDYTQMNELQRRLGPRGLVVLGFPCNQFGHQENAKNGEILNCLKYVRPGGGFEPNFMLFEKCEVNGANAHPLFAFLREALPTPSDDATALMTDPKFITWSPVCRNDIAWNFEKFLVGPDGVPLRRYSRRFLTIDIEPDIEALLSQEPSSA

Gene
GPX1
Protein
Glutathione peroxidase 1
Organism
Bos taurus
Length
205 amino acids
Function
Protects the hemoglobin in erythrocytes from oxidative breakdown.
Similarity
Belongs to the glutathione peroxidase family.
Mass
22.659 kDa
Sequence
MCAAQRSAAALAAAAPRTVYAFSARPLAGGEPFNLSSLRGKVLLIENVASLUGTTVRDYTQMNDLQRRLGPRGLVVLGFPCNQFGHQENAKNEEILNCLKYVRPGGGFEPNFMLFEKCEVNGEKAHPLFAFLREVLPTPSDDATALMTDPKFITWSPVCRNDVSWNFEKFLVGPDGVPVRRYSRRFLTIDIEPDIETLLSQGASA

Gene
GPX1
Protein
Glutathione peroxidase 1
Organism
Homo sapiens
Length
203 amino acids
Function
Protects the hemoglobin in erythrocytes from oxidative breakdown.
Similarity
Belongs to the glutathione peroxidase family.
Mass
22.088 kDa
Sequence
MCAARLAAAAAAAQSVYAFSARPLAGGEPVSLGSLRGKVLLIENVASLUGTTVRDYTQMNELQRRLGPRGLVVLGFPCNQFGHQENAKNEEILNSLKYVRPGGGFEPNFMLFEKCEVNGAGAHPLFAFLREALPAPSDDATALMTDPKLITWSPVCRNDVAWNFEKFLVGPDGVPLRRYSRRFQTIDIEPDIEALLSQGPSCA

Gene
GPX1
Protein
Glutathione peroxidase 1
Organism
Pongo pygmaeus
Length
201 amino acids
Function
Protects the hemoglobin in erythrocytes from oxidative breakdown.
Similarity
Belongs to the glutathione peroxidase family.
Mass
21.99 kDa
Sequence
MCAARLVAAAAQSVYSFSARPLAGGEPVSLGSLRGKVLLIENVASLUGTTVRDYTQMNELQRRLGPRGLVVLGFPCNQFGHQENAKNEEILNSLKYVRPGGGFEPNFMLFEKCEVNGAGAHPLFAFLREALPAPSDDATALMTDPKLITWSPVCRNDVAWNFEKFLVGPDGVPLRRYSRRFQTIDIEPDIEALLSQGPSCA

Gene
Gpx1
Protein
Glutathione peroxidase 1
Organism
Rattus norvegicus
Length
201 amino acids
Function
Protects the hemoglobin in erythrocytes from oxidative breakdown.
Similarity
Belongs to the glutathione peroxidase family.
Mass
22.305 kDa
Sequence
MSAARLSAVAQSTVYAFSARPLAGGEPVSLGSLRGKVLLIENVASLUGTTTRDYTEMNDLQKRLGPRGLVVLGFPCNQFGHQENGKNEEILNSLKYVRPGGGFEPNFTLFEKCEVNGEKAHPLFTFLRNALPAPSDDPTALMTDPKYIIWSPVCRNDISWNFEKFLVGPDGVPVRRYSRRFRTIDIEPDIEALLSKQPSNP

Gene
GPX1
Protein
Glutathione peroxidase 1
Organism
Sapajus apella
Length
201 amino acids
Function
Protects the hemoglobin in erythrocytes from oxidative breakdown.
Similarity
Belongs to the glutathione peroxidase family.
Mass
21.785 kDa
Sequence
MCAAGLAAAAAQSVYAFSARQLAGGEPVSLGSLRCKGLLIENVASLUGTTVRDYTQMNEPQRRLGPRGLVVLGFPCNHSGHQENAKNEEILNSLKYVRPGGGFEPNFMLFEKGEVNGAGAHTLFAFLREALPAPSDDATALMIDPKLITWSPVCRNDVAWNFEKFLVGPDGVPLRRYSRRFQTIDIEPDIEALLSQGPSCA

Gene
GPX1
Protein
Glutathione peroxidase 1
Organism
Pongo pygmaeus
Length
201 amino acids
Function
Protects the hemoglobin in erythrocytes from oxidative breakdown.
Similarity
Belongs to the glutathione peroxidase family.
Mass
21.99 kDa
Sequence
MCAARLVAAAAQSVYSFSARPLAGGEPVSLGSLRGKVLLIENVASLUGTTVRDYTQMNELQRRLGPRGLVVLGFPCNQFGHQENAKNEEILNSLKYVRPGGGFEPNFMLFEKCEVNGAGAHPLFAFLREALPAPSDDATALMTDPKLITWSPVCRNDVAWNFEKFLVGPDGVPLRRYSRRFQTIDIEPDIEALLSQGPSCA

Gene
Gpx1
Protein
Glutathione peroxidase 1
Organism
Rattus norvegicus
Length
201 amino acids
Function
Protects the hemoglobin in erythrocytes from oxidative breakdown.
Similarity
Belongs to the glutathione peroxidase family.
Mass
22.305 kDa
Sequence
MSAARLSAVAQSTVYAFSARPLAGGEPVSLGSLRGKVLLIENVASLUGTTTRDYTEMNDLQKRLGPRGLVVLGFPCNQFGHQENGKNEEILNSLKYVRPGGGFEPNFTLFEKCEVNGEKAHPLFTFLRNALPAPSDDPTALMTDPKYIIWSPVCRNDISWNFEKFLVGPDGVPVRRYSRRFRTIDIEPDIEALLSKQPSNP

Gene
GPX1
Protein
Glutathione peroxidase 1
Organism
Sapajus apella
Length
201 amino acids
Function
Protects the hemoglobin in erythrocytes from oxidative breakdown.
Similarity
Belongs to the glutathione peroxidase family.
Mass
21.785 kDa
Sequence
MCAAGLAAAAAQSVYAFSARQLAGGEPVSLGSLRCKGLLIENVASLUGTTVRDYTQMNEPQRRLGPRGLVVLGFPCNHSGHQENAKNEEILNSLKYVRPGGGFEPNFMLFEKGEVNGAGAHTLFAFLREALPAPSDDATALMIDPKLITWSPVCRNDVAWNFEKFLVGPDGVPLRRYSRRFQTIDIEPDIEALLSQGPSCA

Gene
GPX1
Protein
Glutathione peroxidase 1
Organism
Callithrix jacchus
Length
201 amino acids
Function
Protects the hemoglobin in erythrocytes from oxidative breakdown.
Similarity
Belongs to the glutathione peroxidase family.
Mass
21.785 kDa
Sequence
MCAAGLAAAAAQSVYAFSARQLAGGEPVSLGSLRCKGLLIENVASLUGTTVRDYTQMNEPQRRLGPRGLVVLGFPCNHSGHQENAKNEEILNSLKYVRPGGGFEPNFMLFEKGEVNGAGAHTLFAFLREALPAPSDDATALMIDPKLITWSPVCRNDVAWNFEKFLVGPDGVPLRRYSRRFQTIDIEPDIEALLSQGPSCA

Gene
GPX1
Protein
Glutathione peroxidase 1
Organism
Hylobates lar
Length
201 amino acids
Function
Protects the hemoglobin in erythrocytes from oxidative breakdown.
Similarity
Belongs to the glutathione peroxidase family.
Mass
21.99 kDa
Sequence
MCAARLAAAAAQSVYAFSARPLTGGEPVSLGSLRGKILLIENVASLUGTTVRDYTQMNELQRRLGPRGLVVLGFPCNQFGHQENAKNEEILNSLKYVRPGGGFEPNFMLFEKCEVNGAGAHPLFAFLREALPAPSDDATALMTDPKLITWSPVCRNDVAWNFEKFLVGPDGVPLRRYSRRFQTIDIEPDIEALLSQGPSCA

Gene
GPX1
Protein
Glutathione peroxidase 1
Organism
Macaca fuscata fuscata
Length
201 amino acids
Function
Protects the hemoglobin in erythrocytes from oxidative breakdown.
Similarity
Belongs to the glutathione peroxidase family.
Mass
21.886 kDa
Sequence
MCAARLAAAAAQSVYAFSARPLAGGEPVSLGSLRGKVLLIENVASLUGTTVRDYTQMNELQRRLGPRGLVVLGFPCNQFGHQENAKNEEILNSLKYVRPGGGFEPNFMLFEKCEVNGAGAHPLFAFLREALPAPSDDATALMTDPKLIAWSPVCRNDVAWNFEKFLVGPDGVPVRRYSRRFQTIDIEPDIEALLSQGPSSA

Gene
Gpx1
Protein
Glutathione peroxidase 1
Organism
Mus musculus
Length
201 amino acids
Function
Protects the hemoglobin in erythrocytes from oxidative breakdown.
Similarity
Belongs to the glutathione peroxidase family.
Mass
22.329 kDa
Sequence
MCAARLSAAAQSTVYAFSARPLTGGEPVSLGSLRGKVLLIENVASLUGTTIRDYTEMNDLQKRLGPRGLVVLGFPCNQFGHQENGKNEEILNSLKYVRPGGGFEPNFTLFEKCEVNGEKAHPLFTFLRNALPTPSDDPTALMTDPKYIIWSPVCRNDIAWNFEKFLVGPDGVPVRRYSRRFRTIDIEPDIETLLSQQSGNS

Gene
GPX1
Protein
Glutathione peroxidase 1
Organism
Pan troglodytes
Length
201 amino acids
Function
Protects the hemoglobin in erythrocytes from oxidative breakdown.
Similarity
Belongs to the glutathione peroxidase family.
Mass
21.95 kDa
Sequence
MCAARLAAAAAQSVYAFSARPLAGGEPVSLGSLRGKVLLIENVASLUGTTVRDYTQMNELQRRLGPRGLVVLGFPCNQFGHQENAKNEEILNSLKYVRPGGGFEPNFMLFEKCEVNGAGAHTLFAFLREALPAPSDDATALMTDPKLITWSPVCRNDVAWNFEKFLVGPDGVPLRRYSRRFQTIDIEPDIEALLSQGPSCA

Gene
GPX1
Protein
Glutathione peroxidase 1
Organism
Oryctolagus cuniculus
Length
200 amino acids
Function
Protects the hemoglobin in erythrocytes from oxidative breakdown.
Similarity
Belongs to the glutathione peroxidase family.
Mass
21.883 kDa
Sequence
MCAARMAAAAQSVYSFSAHPLAGGEPVNLGSLRGKVLLIENVASLUGTTVRDYTQMNELQERLGPRALVVLGFPCNQFGHQENAKNEEILNSLKYVRPGGGFEPNFMLFQKCEVNGAKASPLFAFLREALPPPSDDPTALMTDPKFITWCPVCRNDVSWSFEKFLVGPDGVPVRRYSRRFPTIDIEPDIQALLSKGSGGA

Gene
GPX1
Protein
Glutathione peroxidase 1
Organism
Oryctolagus cuniculus
Length
200 amino acids
Function
Protects the hemoglobin in erythrocytes from oxidative breakdown.
Similarity
Belongs to the glutathione peroxidase family.
Mass
21.883 kDa
Sequence
MCAARMAAAAQSVYSFSAHPLAGGEPVNLGSLRGKVLLIENVASLUGTTVRDYTQMNELQERLGPRALVVLGFPCNQFGHQENAKNEEILNSLKYVRPGGGFEPNFMLFQKCEVNGAKASPLFAFLREALPPPSDDPTALMTDPKFITWCPVCRNDVSWSFEKFLVGPDGVPVRRYSRRFPTIDIEPDIQALLSKGSGGA

Gene
GPX1
Protein
Glutathione peroxidase
Organism
Schistosoma mansoni
Length
169 amino acids
Similarity
Belongs to the glutathione peroxidase family.
Mass
19.471 kDa
Sequence
MSSSHKSWNSIYEFTVKDINGVDVSLEKYRGHVCLIVNVACKUGATDKNYRQLQEMHTRLVGKGLRILAFPCNQFGGQEPWAEAEIKKFVTEKYGVQFDMFSKIKVNGSDADDLYKFLKSRQHGTLTNNIKWNFSKFLVDRQGQPVKRYSPTTAPYDIEGDIMELLEKK

Gene
gpx1
Protein
Hydroperoxy fatty acid reductase gpx1
Organism
Synechocystis sp. (strain PCC 6803 / Kazusa)
Length
169 amino acids
Function
Hydroperoxy fatty acid reductase essential for the removal of lipid hydroperoxides under normal and stress conditions, leading to the protection of membrane integrity.
Similarity
Belongs to the glutathione peroxidase family.
Mass
18.452 kDa
Sequence
MTAQANNTIYGFSANALDGSPVALRDFEGKVLLIVNTASQCGFTPQYQGLQALYNRFGDRGFTVLGFPCNQFGQQEPGGSGEIKNFCETRYGVTFPLFEKVEVNGPNAHPLFKFLTAASPGMAIPFLGGAEDIKWNFTKFLVDRQGKVVKRYGSIAKPDEIAADIEKLL

Gene
GPX1
Protein
Glutathione peroxidase
Organism
Schistosoma mansoni
Length
169 amino acids
Similarity
Belongs to the glutathione peroxidase family.
Mass
19.471 kDa
Sequence
MSSSHKSWNSIYEFTVKDINGVDVSLEKYRGHVCLIVNVACKUGATDKNYRQLQEMHTRLVGKGLRILAFPCNQFGGQEPWAEAEIKKFVTEKYGVQFDMFSKIKVNGSDADDLYKFLKSRQHGTLTNNIKWNFSKFLVDRQGQPVKRYSPTTAPYDIEGDIMELLEKK

Gene
gpx1
Protein
Hydroperoxy fatty acid reductase gpx1
Organism
Synechocystis sp. (strain PCC 6803 / Kazusa)
Length
169 amino acids
Function
Hydroperoxy fatty acid reductase essential for the removal of lipid hydroperoxides under normal and stress conditions, leading to the protection of membrane integrity.
Similarity
Belongs to the glutathione peroxidase family.
Mass
18.452 kDa
Sequence
MTAQANNTIYGFSANALDGSPVALRDFEGKVLLIVNTASQCGFTPQYQGLQALYNRFGDRGFTVLGFPCNQFGQQEPGGSGEIKNFCETRYGVTFPLFEKVEVNGPNAHPLFKFLTAASPGMAIPFLGGAEDIKWNFTKFLVDRQGKVVKRYGSIAKPDEIAADIEKLL

Gene
GPX1
Protein
Glutathione peroxidase-like peroxiredoxin 1
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Length
167 amino acids
Function
Glutathione peroxidase-like protein that protects cells from phospholipid hydroperoxides and nonphospholipid peroxides during oxidative stress (PubMed:10480913, PubMed:11445588). Has peroxidase activity using thioredoxin or glutathione as a reducing power. Involved in peroxisome formation (PubMed:22659048).
Similarity
Belongs to the glutathione peroxidase family.
Mass
19.485 kDa
Sequence
MQEFYSFSPIDENGNPFPFNSLRNKVVLIVNVASHCAFTPQYKELEYLYEKYKSHGLVIVAFPCGQFGNQEFEKDKEINKFCQDKYGVTFPILHKIRCNGQKQDPVYKFLKNSVSGKSGIKMIKWNFEKFVVDRNGKVVKRFSCMTRPLELCPIIEELLNQPPEEQI

Gene
GPX1
Protein
Glutathione peroxidase-like peroxiredoxin 1
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Length
167 amino acids
Function
Glutathione peroxidase-like protein that protects cells from phospholipid hydroperoxides and nonphospholipid peroxides during oxidative stress (PubMed:10480913, PubMed:11445588). Has peroxidase activity using thioredoxin or glutathione as a reducing power. Involved in peroxisome formation (PubMed:22659048).
Similarity
Belongs to the glutathione peroxidase family.
Mass
19.485 kDa
Sequence
MQEFYSFSPIDENGNPFPFNSLRNKVVLIVNVASHCAFTPQYKELEYLYEKYKSHGLVIVAFPCGQFGNQEFEKDKEINKFCQDKYGVTFPILHKIRCNGQKQDPVYKFLKNSVSGKSGIKMIKWNFEKFVVDRNGKVVKRFSCMTRPLELCPIIEELLNQPPEEQI

Gene
gpx1
Protein
Glutathione peroxidase-like peroxiredoxin gpx1
Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843)
Length
158 amino acids
Function
Glutathione peroxidase-like protein that protects cells during oxidative stress. Has peroxidase activity reducing hydrogen peroxide, alkyl and phospholipid hydroperoxides using preferentially thioredoxin as a reducing power. May act as a scavenger of H(2)O(2).
Similarity
Belongs to the glutathione peroxidase family.
Mass
18.061 kDa
Sequence
MSHFYDLAPKDKDGNPFPFSNLKGKVVLVVNTASKCGFTPQYKGLEALYQKYKDRGFIILGFPCNQFGNQEPGSDEEIAQFCQKNYGVTFPVLAKINVNGDNVDPVYQFLKSQKKQLGLERIKWNFEKFLVNRQGQVIERYSSISKPEHLENDIESVL

Gene
gpx1
Protein
Glutathione peroxidase-like peroxiredoxin gpx1
Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843)
Length
158 amino acids
Function
Glutathione peroxidase-like protein that protects cells during oxidative stress. Has peroxidase activity reducing hydrogen peroxide, alkyl and phospholipid hydroperoxides using preferentially thioredoxin as a reducing power. May act as a scavenger of H(2)O(2).
Similarity
Belongs to the glutathione peroxidase family.
Mass
18.061 kDa
Sequence
MSHFYDLAPKDKDGNPFPFSNLKGKVVLVVNTASKCGFTPQYKGLEALYQKYKDRGFIILGFPCNQFGNQEPGSDEEIAQFCQKNYGVTFPVLAKINVNGDNVDPVYQFLKSQKKQLGLERIKWNFEKFLVNRQGQVIERYSSISKPEHLENDIESVL