GPRASP1

G-protein coupled receptor-associated sorting protein 1

1395 amino acids

Modulates lysosomal sorting and functional down-regulation of a variety of G-protein coupled receptors. Targets receptors for degradation in lysosomes via its interaction with BECN2.

Belongs to the GPRASP family.

156.865 kDa

MTGAEIESGAQVKPEKKPGEEVVGGAEIENDVPLVVRPKVRTQAQIMPGARPKNKSKVMPGASTKVETSAVGGARPKSKAKAIPVSRFKEEAQMWAQPRFGAERLSKTERNSQTNIIASPLVSTDSVLVAKTKYLSEDRELVNTDTESFPRRKAHYQAGFQPSFRSKEETNMGSWCCPRPTSKQEASPNSDFKWVDKSVSSLFWSGDEVTAKFHPGNRVKDSNRSMHMANQEANTMSRSQTNQELYIASSSGSEDESVKTPWFWARDKTNTWSGPREDPNSRSRFRSKKEVYVESSSGSEHEDHLESWFGAGKEAKFRSKMRAGKEANNRARHRAKREACIDFMPGSIDVIKKESCFWPEENANTFSRPMIKKEARARAMTKEEAKTKARARAKQEARSEEEALIGTWFWATDESSMADEASIESSLQVEDESIIGSWFWTEEEASMGTGASSKSRPRTDGERIGDSLFGAREKTSMKTGAEATSESILAADDEQVIIGSWFWAGEEVNQEAEEETIFGSWFWVIDAASVESGVGVSCESRTRSEEEEVIGPWFWSGEQVDIEAGIGEEARPGAEEETIFGSWFWAENQTYMDCRAETSCDTMQGAEEEEPIIGSWFWTRVEACVEGDVNSKSSLEDKEEAMIPCFGAKEEVSMKHGTGVRCRFMAGAEETNNKSCFWAEKEPCMYPAGGGSWKSRPEEEEDIVNSWFWSRKYTKPEAIIGSWLWATEESNIDGTGEKAKLLTEEETIINSWFWKEDEAISEATDREESRPEAEEGDIIGSWFWAGEEDRLEPAAETREEDRLAAEKEGIVGSWFGAREETIRREAGSCSKSSPKAEEEEVIIGSWFWEEEASPEAVAGVGFESKPGTEEEEITVGSWFWPEEEASIQAGSQAVEEMESETEEETIFGSWFWDGKEVSEEAGPCCVSKPEDDEEMIVESWFWSRDKAIKETGTVATCESKPENEEGAIVGSWFEAEDEVDNRTDNGSNCGSRTLADEDEAIVGSWFWAGDEAHFESNPSPVFRAICRSTCSVEQEPDPSRRPQSWEEVTVQFKPGPWGRVGFPSISPFRFPKEAASLFCEMFGGKPRNMVLSPEGEDQESLLQPDQPSPEFPFQYDPSYRSVQEIREHLRAKESTEPESSSCNCIQCELKIGSEEFEELLLLMEKIRDPFIHEISKIAMGMRSASQFTRDFIRDSGVVSLIETLLNYPSSRVRTSFLENMIRMAPPYPNLNIIQTYICKVCEETLAYSVDSPEQLSGIRMIRHLTTTTDYHTLVANYMSGFLSLLATGNAKTRFHVLKMLLNLSENLFMTKELLSAEAVSEFIGLFNREETNDNIQIVLAIFENIGNNIKKETVFSDDDFNIEPLISAFHKVEKFAKELQGKTDNQNDPEGDQEN

Gprasp1

G-protein coupled receptor-associated sorting protein 1

1347 amino acids

Modulates lysosomal sorting and functional down-regulation of a variety of G-protein coupled receptors. Targets receptors for degradation in lysosomes via its interaction with BECN2.

Belongs to the GPRASP family.

151.745 kDa

MTRAEVEPGAQAKAENKPGDENANAAEVEPEAPLVVRPKVRTQIMTGARPKVKPKGTPGARPKGETSTPGGAYAKCKPKAIPIARSKHDAQVWAPNKFRGESMSKMGKQCQISAADPPLLSNDSGMVAQAKCLPVDRELANMDTESIPKKANSPAGFQPSYGSEEGTNMGSWYRARPVPKGEAYENSDFKWADKPSGSPSFWNRDEASTRFRPRKSMKANNRFRHMAKQEANTMPRHKNKQEFYNISSSDSEDESGKTPWFWPKDKTKVWSKPKEEPNSRSWFRSKKEVRVESTSGSECENPTKSLFWSGEEAKSRSKPRARKGVNMRARQQAKREACSDAMSGAIDTNKKESWFLPEEKANVFSKSKTKKEPRTRAVPKEEVKTKARASTKQEARPEEEVLVGAWFWDTQESTMADRISIKTTFVEEEPIVGDWFWSEEEASVDSETCHTSRPRAKEEQVSSFCLGSGKKSSMESGPKATSKSMPVAKEDEVVIGSWFWADDEEINLQADDESIFGSWFWGTGENSLRSVGVNCEKMPKAGEKEVTDSWFWAGDVNTEAEVEEQARSASTKATIFVPWFWSEKQPNMDLGSEPCSDIMAGAEEEPIIGPWFWAKVDNSVEAEVNSKSSLEDEEEPIRSPWFGAREQTDMKYAAGIRYKPMAEAEDANKKSCVWAKEPCLYPTNRECLKSTLGEKEDTVDPWLWSNNYPRTKTITGSWLWAAEEGNIDDETGEKIKLPTLEDNAFNSWFWKENEESIVEAPKREEFRPEAEEEDIIGSWFWAGDEDRFEPAAKINEENKIASEDEDTVGSWFWGNEEASLEAVRRGTFESAPGIKEEKVTGSWFWTDKAKVGAGSQTVETGSETEEEAIFESLIWAAKKDSIQAGVKRVSKPKDDGNIAVGSWLWSSDKATKEAKTLIVSEASPENGKESVVKFGSRAKDEVINKTGSGDNCKHSTEAETIVGAWFWEGDEASFESNPVPVCKAVCEPESSAEHEPDPSRRPQSWDEVTVQFKAGPWGKAGFPPMNPFRFPKEAASLFAEMFGGKPKLVEVGPEREPEPQFPFQYDPSYRSVREIREHLKARESAQPENWSCNCIQCELRIGSEEFEELLLLMDRNRDPFIHEISKIAMGMRGASQFTRDFIRNSGVVSLIEALLNYPSSRVRTRFLENMVRMAPPYPDLNMIETYVCQICEDTFDYDLDSPDQLSGLTMITHLTATSDYHKVVVNYLAGFFYLLNSGNTKTRFHVLKLLLNLSENLVMTKRLLVTDSVSEFMDLINREESDENIQIVLAIFETISKHIQKEALFSDDDDDDEEEDAVNLEPFISAFREAEKIAKELKRKPGNQKAP

Gprasp1

G-protein coupled receptor-associated sorting protein 1

1346 amino acids

Modulates lysosomal sorting and functional down-regulation of a variety of G-protein coupled receptors. Targets receptors for degradation in lysosomes via its interaction with BECN2 (By similarity).

Belongs to the GPRASP family.

151.349 kDa

MTGAEVEPGAQAKAENKPGDENANAAEVEPEVPLVVRPKVRTQMMTGARPKVKPKGTPGARPKGETSSPGGAYAKCKPRSIPISRSKHDAQVWAPSKFRGESMSKMGKQCQISAADSPLVSNDSGAVAQAKCLSVDRELANMDTESIPKKASSPARFQPSFGPEEGTSMGSWYRPRPIPKGEAYENSDFKWADKSSGSSSFWNRDETSTRFRPRKSMKSNTRFRHMAKQEANTMSRHKNKQEFYNISSSDSEDESAKTPWFWAKDKPKVWSRPKEEPNTRSWFRSKKEVRVESTSGSECENHTKSLFWSGEEAKCRSKPRARKGVNMRARHQAKREAYSDVTSGSVDKNKKDSWFLPEEKANAFSKSKTKKEPRTRAMPREEVKTKARASTKQEARPEEEVLVGAWVLDTQDNTMGERISMKTTCVEEEPIVGDWFWSEEEASVDSETGLKSRPRAKEEQVSSFCLGSGKKTSMESGPKATSKSMPVAKDDEVIIGSWFWADDEEISLQADDESIFGSWFWGTGEKSLRSVGVSCEKMPKSGEKEVTDSWFWAGEVNTEAEMEEQASSASTKGTIFVPWFWSEKQAHMDLGTEPCSDIMAGAEEEPIIGPWFWAKVDNSVEAEVNSKSSLEDEEEPIRSPWFGAREQPNMKYAAGVGYKPMAEAEEANKKSCVWAKEPCLYPTNRESLKSTLGEKEDTVDPWLWSNNYPRTETITGSWLWAAEEGNIDDETGEEIKLPTLEDNVFNSWSWKENEETVVEAPNREESKPEAEEEDIIGSWFWAGDEDRFQPAAKIKEENKIAPEDEDTVGSWFWGKEEASVEAVKGGTFESVSGIKEEKATGSWFWTDKAKIGAGPQTVETGSETEDEAIFESLIWAAKKDSMQTGVNRVSKPKDEGEGIESWLWSGDKATTESKTVTVSESSPENGKESIVKFGSRAKDEVINKTGSGDNCKFSTEAESIVGPWFWEGDEASFESNPVPVCKAACEPESSTEHEPDPSRRPQSWDEVTVQFKPGPWGKAGFPSLNPFRFPKEAASLFAEMFGGKPKLVEVGTEREPEPQFPFQYDPSYRSVREIREHLKARESAQAENWSCNCIQCELRIGSEEFEELLLMMDRNRDPFIHEISKIAMGMRGASQFTRDFIRNSGVISLIEALMNYPSSRARTAFLENMIQMAPTYPDLNMIETYVCQVCEDTFDYDLDSSDQLSGLTMITHLTTTFDYHKVVVAYLAGFYYLLNSGNTTTRFHVLKLLLNLSESLVMTKRLLITDSVSEFMALFNREDSDENIQIILAIFENISKNIQKEALFADDEEEEEEEEAVNLEPLISAFREAEKFAKELKRKTDDQKSP