GPN3

Gene

gpn3

Protein

GPN-loop GTPase 3

Organism

Danio rerio

Length

285 amino acids

Function

Small GTPase required for proper localization of RNA polymerase II (RNAPII). May act at an RNAP assembly step prior to nuclear import.

Similarity

Belongs to the GPN-loop GTPase family.

Mass

32.626 kDa

Sequence

MPRYAQLVMGPAGSGKSTYCATMLEHCQALNRSVQVVNLDPAAEHFEYPVIADIRELIQVDDVMEDDSLRFGPNGGLIFCMEYFSNNFDWLEESLGHVEDDYILFDCPGQIELYTHLPVMKQLVEQLQQWEFRVCGVFLVDSQFMVETFKFISGVMAALSAMVMLEIPQVNIMTKMDLLSPKAKKEIEKYLDPDMYSMMEDNSVALRSKKFSKLTKAICGLIDDYSMVRFLPFDRTDEEGINIVLQHIDFSIQYGEDLEVKEPKEVDEEPSNSNFDAFFQDTADS

Protein

GPN-loop GTPase 3: gpn3

Gene

gpn3

Protein

GPN-loop GTPase 3

Organism

Dictyostelium discoideum

Length

285 amino acids

Function

Small GTPase required for proper localization of RNA polymerase II (RNAPII). May act at an RNAP assembly step prior to nuclear import.

Similarity

Belongs to the GPN-loop GTPase family.

Mass

32.514 kDa

Sequence

MGKHVQLVMGPAGSGKSTYCDTMRKYCEEIKRSVHIVNLDPAAEVFEYPVSVDIKNLVTVDEVMDELHYGPNGGLVYAMEYLIENMDWLTDELGDYEDDYLIIDCPGQIELYSHIPVMRILVDHLQQIGYSVCSVFLVDSQFILDNCKFISGALMCLSAMVRLEVPHINVLTKIDVLKTSDQYKEIEKFLDLEVQNLVEELNLETHDRYHRMNKAIGSLLEDFSLVGFVPLDITDQESLNVLLQHIDNSIQYGEDLEPKEPPLENDDDDDDDEGDEIIRMMNGNL

Protein

GPN-loop GTPase 3: gpn3

Gene

gpn3

Protein

GPN-loop GTPase 3

Organism

Xenopus laevis

Length

285 amino acids

Function

Small GTPase required for proper localization of RNA polymerase II (RNAPII). May act at an RNAP assembly step prior to nuclear import.

Similarity

Belongs to the GPN-loop GTPase family.

Mass

33.058 kDa

Sequence

MPRYAQLVMGPAGSGKSTYCSTMVQHCETLNRSVQVVNLDPAAEHFDYPVLADIRELIEVDDVMEDRSLRFGPNGGLVYCMEYFANNFDWLESCLGHTEDDYILFDCPGQIELYTHLPVMKYLVEQLQQWEFRVCGVFLVDSQFMVESFKFLSGVLAALSAMVSLEIPQCNIMTKMDLLSKKAKKEIEKFLDPDMYSMIEDTPSRFKSTKFKKLTEALCGLVDDYSMVRFLPFDRSDEECMNIVLQHIDFAIQYGEDLEFKEPRENEEDKSENFDEYFQDRTDES

Protein

GPN-loop GTPase 3: gpn3

Gene

gpn3

Protein

GPN-loop GTPase 3

Organism

Xenopus tropicalis

Length

285 amino acids

Function

Small GTPase required for proper localization of RNA polymerase II (RNAPII). May act at an RNAP assembly step prior to nuclear import.

Similarity

Belongs to the GPN-loop GTPase family.

Mass

32.921 kDa

Sequence

MPRYAQLVMGPAGSGKSTYCSTMVQHCGSLNRSVQVVNLDPAAEHFDYPVLADIRELIEVDDVMEDRSLRFGPNGGLVYCMEYFANNFDWLESCLGHTEDDYILFDCPGQIELYTHLPVMKYLVEQLQQWEFRVCGVFLVDSQFMVESFKFLSGVLAALSAMVSLEIPQCNIMTKMDLLGKKAKKEIEKFLDPDMYSMIEDTSNRFKSNKFKKLTEALCGLIDDYSMVRFLPFDRSDEECMNIVLQHIDFAIQYGEDLEFKEPKENEEDKSENFDEFFQDRADEP

Protein

GPN-loop GTPase 3: gpn3

Gene

GPN3

Protein

GPN-loop GTPase 3

Organism

Bos taurus

Length

284 amino acids

Function

Small GTPase required for proper localization of RNA polymerase II (RNAPII). May act at an RNAP assembly step prior to nuclear import.

Similarity

Belongs to the GPN-loop GTPase family.

Mass

32.691 kDa

Sequence

MPRYAQLVMGPAGSGKSTYCATMVQHCEALNRSVQVVNLDPAAEHFNYSVMADIRELIEVDDVMEDSTLQFGPNGGLVFCMEYFANNFDWLENCLGHVEDDYILFDCPGQIELYTHLPVMKQLVQQLEQWEFRVCGVFLVDSQFMVESFKFISGILAALSAMISLEIPQVNVMTKMDLLSKKAKKEIEKFLDPDMYSLLDDSTSDLRSKKFKKLTNAICGLIDDYSMVRFLPYDQSDEESMNIVLQHIDFAIQYGEDLEFKEPKEHEDESSSMFDEYFQEHQNE

Protein

GPN-loop GTPase 3: GPN3

Gene

GPN3

Protein

GPN-loop GTPase 3

Organism

Homo sapiens

Length

284 amino acids

Function

Small GTPase required for proper localization of RNA polymerase II (RNAPII). May act at an RNAP assembly step prior to nuclear import.

Similarity

Belongs to the GPN-loop GTPase family.

Mass

32.761 kDa

Sequence

MPRYAQLVMGPAGSGKSTYCATMVQHCEALNRSVQVVNLDPAAEHFNYSVMADIRELIEVDDVMEDDSLRFGPNGGLVFCMEYFANNFDWLENCLGHVEDDYILFDCPGQIELYTHLPVMKQLVQQLEQWEFRVCGVFLVDSQFMVESFKFISGILAALSAMISLEIPQVNIMTKMDLLSKKAKKEIEKFLDPDMYSLLEDSTSDLRSKKFKKLTKAICGLIDDYSMVRFLPYDQSDEESMNIVLQHIDFAIQYGEDLEFKEPKEREDESSSMFDEYFQECQDE

Protein

GPN-loop GTPase 3: GPN3

Gene

Gpn3

Protein

GPN-loop GTPase 3

Organism

Mus musculus

Length

284 amino acids

Function

Small GTPase required for proper localization of RNA polymerase II (RNAPII). May act at an RNAP assembly step prior to nuclear import.

Similarity

Belongs to the GPN-loop GTPase family.

Mass

32.79 kDa

Sequence

MPRYAQLVMGPAGSGKSTYCSTMVQHCEALNRSVQVVNLDPAAEHFNYPVMADIRELIEVDDVMEDESLRFGPNGGLVFCMEYFANNFDWLENCLGHVEDDYILFDCPGQIELYTHLPVMKQLVQQLEQWEFRVCGVFLVDSQFMVESFKFISGILAALSAMVSLEIPQVNIMTKMDLLSKKAKKEIEKFLDPDMYSLIDDSTGDLRSQKFKKLTKAVCGLVDDYSMVRFLPYDQSDEESMNIVLQHIDFAIQYGEDLEFKEPREHEEESSSMFDEYFQERQNE

Protein

GPN-loop GTPase 3: Gpn3

Gene

Gpn3

Protein

GPN-loop GTPase 3

Organism

Rattus norvegicus

Length

284 amino acids

Function

Small GTPase required for proper localization of RNA polymerase II (RNAPII). May act at an RNAP assembly step prior to nuclear import.

Similarity

Belongs to the GPN-loop GTPase family.

Mass

32.802 kDa

Sequence

MPRYAQLVMGPAGSGKSTYCSTMVQHCEALNRSVQVVNLDPAAEHFNYPVMADIRELIEVDDVMEDDSLRFGPNGGLVFCMEYFANNFDWLENCLGHVEDDYILFDCPGQIELYTHLPVMKQLVQQLEQWEFRVCGVFLVDSQFMVESFKFISGILAALSAMISLEIPQVNIMTKMDLLSKKAKKEIEKFLDPDMYSLLEDSTGDLRSQKFKKLTKPVCGLVDDYSMVRFLPYDQSDEESMNIVLQHIDFAIQYGEDLEFKEPKEHEEESSSMFDEYFQERQNE

Protein

GPN-loop GTPase 3: Gpn3

Gene

GPN3

Protein

GPN-loop GTPase 3

Organism

Saccharomyces cerevisiae (strain ATCC 204508 / S288c)

Length

272 amino acids

Function

Small GTPase required for proper nuclear localization of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import (PubMed:23267056). Promotes sister chromatid separation during anaphase (PubMed:23324351).

Similarity

Belongs to the GPN-loop GTPase family.

Mass

30.653 kDa

Sequence

MSRVGVMVLGPAGAGKSTFCNSIISHMQTVGRRAHIVNLDPAAEATKYEFTIDIRDLISLDDVMEEMDLGPNGALIYCFEYLLKNLDWLDEEIGDFNDEYLIFDCPGQIELYTHIPVLPNIVRHLTQQLNFNLCATYLLEAPFVIDSSKFFSGALSAMSAMILLELPHINVLSKLDLIKGDINKKKLKRFLNPDAMLLMETEGMNQASNPKFLRLNQCIANLVDDFGMVQFLPLESNNPDSIETILSYVDDITQWAEGQEQKEPNDQIDVEE

Protein

GPN-loop GTPase 3: GPN3