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GPHB5

Gene
GPHB5
Protein
Glycoprotein hormone beta-5
Organism
Homo sapiens
Length
130 amino acids
Function
Functions as a heterodimeric glycoprotein hormone with GPHA2 able to bind and activate the thyroid-stimulating hormone receptor (TSHR), leading to increased cAMP production. Plays a central role in controlling thyroid cell metabolism.
Similarity
Belongs to the glycoprotein hormones subunit beta family.
Mass
14.232 kDa
Sequence
MKLAFLFLGPMALLLLAGYGCVLGASSGNLRTFVGCAVREFTFLAKKPGCRGLRITTDACWGRCETWEKPILEPPYIEAHHRVCTYNETKQVTVKLPNCAPGVDPFYTYPVAIRCDCGACSTATTECETI

Gene
Gphb5
Protein
Glycoprotein hormone beta-5
Organism
Mus musculus
Length
130 amino acids
Function
Functions as a heterodimeric glycoprotein hormone with GPHA2 able to bind and activate the thyroid-stimulating hormone receptor (TSHR), leading to increased cAMP production. Plays a central role in controlling thyroid cell metabolism.
Similarity
Belongs to the glycoprotein hormones subunit beta family.
Mass
14.249 kDa
Sequence
MKLVYLVLGAVALLLLGGPDSVLSSSSGNLHTFVGCAVREFTFMAKKPGCRGLRITTDACWGRCETWEKPILEPPYIEAYHRVCTYNETRQVTVKLPNCAPGVDPFYTYPMAVRCDCGACSTATTECETI