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GPBAR1

Gene
GPBAR1
Protein
G-protein coupled bile acid receptor 1
Organism
Homo sapiens
Length
330 amino acids
Function
Receptor for bile acid. Bile acid-binding induces its internalization, activation of extracellular signal-regulated kinase and intracellular cAMP production. May be involved in the suppression of macrophage functions by bile acids.
Similarity
Belongs to the G-protein coupled receptor 1 family.
Mass
35.248 kDa
Sequence
MTPNSTGEVPSPIPKGALGLSLALASLIITANLLLALGIAWDRRLRSPPAGCFFLSLLLAGLLTGLALPTLPGLWNQSRRGYWSCLLVYLAPNFSFLSLLANLLLVHGERYMAVLRPLQPPGSIRLALLLTWAGPLLFASLPALGWNHWTPGANCSSQAIFPAPYLYLEVYGLLLPAVGAAAFLSVRVLATAHRQLQDICRLERAVCRDEPSALARALTWRQARAQAGAMLLFGLCWGPYVATLLLSVLAYEQRPPLGPGTLLSLLSLGSASAAAVPVAMGLGDQRYTAPWRAAAQRCLQGLWGRASRDSPGPSIAYHPSSQSSVDLDLN

Gene
GPBAR1
Protein
G-protein coupled bile acid receptor 1
Organism
Oryctolagus cuniculus
Length
330 amino acids
Function
Receptor for bile acid. Bile-acid binding induces its internalization, activation of extracellular signal-regulated kinase and intracellular cAMP production. May be involved in the suppression of macrophage functions by bile acids. Involved in bile acid promoted GLP1R secretion (By similarity).
Similarity
Belongs to the G-protein coupled receptor 1 family.
Mass
35.224 kDa
Sequence
MTPNSTGEVPGPIPRGALELSLALASLIIAANLLLALGIACDRRLRSPPAGCFFLSLLLAGLLTGLALPTLPGLWRQSHRGYWSCLLVYLAPNFSFLSLLANLLLVHGERYVAVLRPLQPPGSIRLALLLTWTGPLLFASLPALGWNHWGPEANCSSQTIFPAPYLYLEVYGLLLPAVGAAALLSAHVLLAAHRQLQDIRRLERAVCRDAPSALARALTWRQARAQAGATLLFGLCWGPYVATLFLSVLAYEQRPPLGPGTLLSLLSLGSASAAAVPVAMGLGDHRYTAPWRAAARRWLRGLRGRGSQASPGPSTAYHTSSQSSVDVDLN

Gene
GPBAR1
Protein
G-protein coupled bile acid receptor 1
Organism
Bos taurus
Length
329 amino acids
Function
Receptor for bile acid. Bile acid-binding induces its internalization, activation of extracellular signal-regulated kinase and intracellular cAMP production. May be involved in the suppression of macrophage functions by bile acids. Involved in bile acid promoted GLP1R secretion (By similarity).
Similarity
Belongs to the G-protein coupled receptor 1 family.
Mass
35.104 kDa
Sequence
MTSNSTREVPSPVPAGALGLSLALASLIVAANLLLAVGIAGDRRLRSPPAGCFFLSLLLAGLLTGLALPALPVLWSQSRRGYWSCLFLYLAPNFCFLSLLANLLLVHGERYMAVLRPLRPRGSMRLALLLTWAAPLLFASLPALGWNHWAPGGNCSSQAVFPAPYLYLEIYGLLLPAVGAAALLSVRVLVTAHRQLQDIRRLERAVCRGAPSALARALTWRQARAQAGATLLFGLCWGPYVATLLLSVLAFEQRPPLGPGTLLSLISLGSASAAAVPVAMGLGDQRYTGPWRVAAQKWLRMLRGRPQSSPGPSTAYHTSSQSSVDLDLN

Gene
Gpbar1
Protein
G-protein coupled bile acid receptor 1
Organism
Mus musculus
Length
329 amino acids
Function
Receptor for bile acid. Bile acid-binding induces its internalization, activation of extracellular signal-regulated kinase and intracellular cAMP production. May be involved in the suppression of macrophage functions by bile acids (By similarity). Involved in bile acid promoted GLP1R secretion.
Similarity
Belongs to the G-protein coupled receptor 1 family.
Mass
35.65 kDa
Sequence
MMTPNSTELSAIPMGVLGLSLALASLIVIANLLLALGIALDRHLRSPPAGCFFLSLLLAGLLTGLALPMLPGLWSRNHQGYWSCLLLHLTPNFCFLSLLANLLLVHGERYMAVLQPLRPHGSVRLALFLTWVSSLFFASLPALGWNHWSPDANCSSQAVFPAPYLYLEVYGLLLPAVGATALLSVRVLATAHRQLCEIRRLERAVCRDVPSTLARALTWRQARAQAGATLLFLLCWGPYVATLLLSVLAYERRPPLGPGTLLSLISLGSTSAAAVPVAMGLGDQRYTAPWRTAAQRCLRVLRGRAKRDNPGPSTAYHTSSQCSIDLDLN

Gene
Gpbar1
Protein
G-protein coupled bile acid receptor 1
Organism
Rattus norvegicus
Length
329 amino acids
Function
Receptor for bile acid. Bile acid-binding induces its internalization, activation of extracellular signal-regulated kinase and intracellular cAMP production. May be involved in the suppression of macrophage functions by bile acids. Involved in bile acid promoted GLP1R secretion (By similarity).
Similarity
Belongs to the G-protein coupled receptor 1 family.
Mass
35.791 kDa
Sequence
MMSHNTTELSAIPRGVQELSLVLASLIVIANLLLALGIVLDRHLRSPPAGCFFLSLLLAGLLTGLALPTLPGLWNRSHQGYWSCLLLHLAPNFCFLSLLANLLLVHGERYMAVLQPLRPHGSVRLALFLTWISSLLFASLPALGWNHWSPGANCSSQAIFPAPYLYLEVYGLLLPAVGATALLSVRVLATAHHQLREIRRLERAVCRDAPSTLARALTWRQARAQAGATLLFLLCWGPYVATLLLSVLAYERRPPLGPVTLLSLISLGSASAAVVPVAMGLGDQRYTAPWRTAAQRWLQVLRGRPKRANPGPSTAYHSSSQCSTDLDLN