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GNRHR

Gene
GNRHR
Protein
Gonadotropin-releasing hormone receptor
Organism
Octopus vulgaris
Length
407 amino acids
Function
Receptor for gonadotropin releasing hormone (GnRH) that mediates the action of GnRH to stimulate the secretion of the gonadotropic hormones luteinizing hormone (LH) and follicle-stimulating hormone (FSH). This receptor mediates its action by association with G-proteins that activate a phosphatidylinositol-calcium second messenger system. Ligand interaction triggers steroidogenesis in spermatozoa and follicles. Appears to be involved in contraction of the radula retractor muscle.
Similarity
Belongs to the G-protein coupled receptor 1 family.
Mass
46.003 kDa
Sequence
MDYLNDSMFNNMTYNITSTPLPDAPRFDNVYVSKLCVLGTVFVISFFGNTLVIIQIFRIRGSRSTIQSLILNLAIADLMVSFFNILMDIIWSATVEWLAGNTMCKIMKYLTVFGLHLSTYITVSIALDRCFAILSPMSRSKAPLRVRIMITMAWVLSAIFSIPQAVIFQEQRKMFRQGMFHQCRDSYNALWQKQLYSASSLILLFVIPLIIMVTSYLLILKTIVKTSRQFHDTPISPTSMSCYSVNHGQIRTHLFERARKRSSRMSAVIVAAFILCWTPYYIIFLGFAFFQWDNSRTVIYFFTLGTSNCMLNPLIYGAFTIYKVHRGRSGSANSPSGTRLMIMVNKRGRSTTTTTNRMSGSGRRQLTTGQTITQCASLTNPHQPVRPSPGINSTTSPNGKMPTKPPG

Gene
GNRHR
Protein
Gonadotropin-releasing hormone receptor
Organism
Ovis aries
Length
328 amino acids
Function
Receptor for gonadotropin releasing hormone (GnRH) that mediates the action of GnRH to stimulate the secretion of the gonadotropic hormones luteinizing hormone (LH) and follicle-stimulating hormone (FSH). This receptor mediates its action by association with G-proteins that activate a phosphatidylinositol-calcium second messenger system.
Similarity
Belongs to the G-protein coupled receptor 1 family.
Mass
37.685 kDa
Sequence
MANGDSPDQNENHCSAINSSILLTPGSLPTLTLSGKIRVTVTFFLFLLSTIFNTSFLLKLQNWTQRKEKRKKLSKMKVLLKHLTLANLLETLIVMPLDGMWNITVQWYAGELLCKVLSYLKLFSMYAPAFMMVVISLDRSLAITRPLAVKSNSKLGQFMIGLAWLLSSIFAGPQLYIFGMIHLADDSGQTEGFSQCVTHCSFPQWWHQAFYNFFTFSCLFIIPLLIMLICNAKIIFTLTRVLHQDPHKLQLNQSKNNIPQARLRTLKMTVAFATSFTVCWTPYYVLGIWYWFDPDMVNRVSDPVNHFFFLFAFLNPCFDPLIYGYFSL

Gene
GNRHR
Protein
Gonadotropin-releasing hormone receptor
Organism
Trichosurus vulpecula
Length
328 amino acids
Function
Receptor for gonadotropin releasing hormone (GnRH) that mediates the action of GnRH to stimulate the secretion of the gonadotropic hormones luteinizing hormone (LH) and follicle-stimulating hormone (FSH). This receptor mediates its action by association with G-proteins that activate a phosphatidylinositol-calcium second messenger system (By similarity).
Similarity
Belongs to the G-protein coupled receptor 1 family.
Mass
37.986 kDa
Sequence
MANRAYLEQKQTQCSIINSSFSMTHRDLPTLTLSGKIRVMVTFFLFLVSTAFNASFLMKLQRQTQKKEEVKKLTRMKVLLKHLTLANLLETVIVMPLDGIWNVTVQWYAGEFLCKALSYLKLFSMYAPAFMMVVISLDRFLAITRPLAVKSNTKVGQSLIAVAWFLSIVLAGPQLYIFRMIYVEDISGQTGNFSQCVTHCSFPEWWQEAFYNLLTFSCLFIGPLLIMLVCNAKIIFTLTQVLHQDPHELQLNRSKNNIPRARLRTLKMTVAFATLFTICWTPYYVLGIWYWFDPEMLNRVSDPVNHFFFLFGLLNPCFDPLIYGYFSL

Gene
GNRHR
Protein
Gonadotropin-releasing hormone receptor
Organism
Bos mutus grunniens
Length
328 amino acids
Function
Receptor for gonadotropin releasing hormone (GnRH) that mediates the action of GnRH to stimulate the secretion of the gonadotropic hormones luteinizing hormone (LH) and follicle-stimulating hormone (FSH). This receptor mediates its action by association with G-proteins that activate a phosphatidylinositol-calcium second messenger system (By similarity).
Similarity
Belongs to the G-protein coupled receptor 1 family.
Mass
37.756 kDa
Sequence
MANSDSPEQNENHCSSINSSIPLTPGSLPTLTLSGKIRVTVTFFLFLLSTIFNTSFLLKLQNWTQRKEKRKKLSRMKLLLKHLTLANLLETLIVMPLDGMWNITVQWYAGELLCKVLSYLKLFSMYAPAFMMVVISLDRSLAITKPLAVKSNSKLGQFMIGLAWLLSSIFAGPQLYIFGMIHLADDSGQTEGFSQCVTHCSFPQWWHQAFYNFFTFSCLFIIPLLIMVICNAKIIFTLTRVLHQDPHKLQLNQSKNNIPRARLRTLKMTVAFATSFTVCWTPYYVLGIWYWFDPDMVNRVSDPVNHFFFLFAFLNPCFNPLIYGYFSL

Gene
GNRHR
Protein
Gonadotropin-releasing hormone receptor
Organism
Bos taurus
Length
328 amino acids
Function
Receptor for gonadotropin releasing hormone (GnRH) that mediates the action of GnRH to stimulate the secretion of the gonadotropic hormones luteinizing hormone (LH) and follicle-stimulating hormone (FSH). This receptor mediates its action by association with G-proteins that activate a phosphatidylinositol-calcium second messenger system.
Similarity
Belongs to the G-protein coupled receptor 1 family.
Mass
37.741 kDa
Sequence
MANSDSPEQNENHCSAINSSIPLTPGSLPTLTLSGKIRVTVTFFLFLLSTIFNTSFLLKLQNWTQRKEKRKKLSRMKLLLKHLTLANLLETLIVMPLDGMWNITVQWYAGELLCKVLSYLKLFSMYAPAFMMVVISLDRSLAITKPLAVKSNSKLGQFMIGLAWLLSSIFAGPQLYIFGMIHLADDSGQTEGFSQCVTHCSFPQWWHQAFYNFFTFSCLFIIPLLIMVICNAKIIFTLTRVLHQDPHKLQLNQSKNNIPRARLRTLKMTVAFATSFTVCWTPYYVLGIWYWFDPDMVNRVSDPVNHFFFLFAFLNPCFDPLIYGYFSL

Gene
GNRHR
Protein
Gonadotropin-releasing hormone receptor
Organism
Cavia porcellus
Length
328 amino acids
Function
Receptor for gonadotropin releasing hormone (GnRH) that mediates the action of GnRH to stimulate the secretion of the gonadotropic hormones luteinizing hormone (LH) and follicle-stimulating hormone (FSH). This receptor mediates its action by association with G-proteins that activate a phosphatidylinositol-calcium second messenger system.
Similarity
Belongs to the G-protein coupled receptor 1 family.
Mass
37.69 kDa
Sequence
MQDDTSSEQNPTHCSAINSSVPLVQGALPTLTLSGKIRVTVTFFLFLVSTTLNASFLLKLQKWTQKKEKGKKLSRMKVLLKHLTLANLLETLIVMPLDGMWNITVQWYAGELLCKILSYLKLFSMYAPAFMMVVISLDRSMAITRPLPVQSNRKLEQSMTGLAWGLSSVLAGPQLYIFKMIHLENGPGQTEVFSQCVTHCSFPQWWHQAFYNFFTFICLFIIPLLIMLICNAKIIFTLTQVLQQDSNKLQLNQSKNNIPRARLRTLKMTVAFAASFIVCWTPYYVLGLWYWFDPGMLHRMSEPVNHFFFLFAFLNPCFDPLIYGYFSL

Gene
GNRHR
Protein
Gonadotropin-releasing hormone receptor
Organism
Equus caballus
Length
328 amino acids
Function
Receptor for gonadotropin releasing hormone (GnRH) that mediates the action of GnRH to stimulate the secretion of the gonadotropic hormones luteinizing hormone (LH) and follicle-stimulating hormone (FSH). This receptor mediates its action by association with G-proteins that activate a phosphatidylinositol-calcium second messenger system (By similarity).
Similarity
Belongs to the G-protein coupled receptor 1 family.
Mass
37.649 kDa
Sequence
MANSASPEQNQNHCSASNSSIPLTQANLPTLTLSGKIRVTVTFFLFLLSTTFNASFLLKLHKWTQKKENGKKLSKMKVLLKHLTLANLLETLIVMPLDGMWNITVQWYAGELLCKVLSYLKLFSMYAPAFMMVVISLDRSLAITRPLAVKSNSKLGRSMIGLAWLLSSIFAGPQLYIFRMIHLADSSGQTEGFSQCVTHCSFPQWWHQAFYNFFTFSCLFIIPLLFMLICNAKIIFTLTRVLHQDPHKLQLNQSKNNIPRARLRTLKMTVAFATSFTVCWTPYYVLGIWYWFDPEMLNRVSDPVNHFFFLFALLNPCFDPLIYGYFSL

Gene
GNRHR
Protein
Gonadotropin-releasing hormone receptor
Organism
Homo sapiens
Length
328 amino acids
Function
Receptor for gonadotropin releasing hormone (GnRH) that mediates the action of GnRH to stimulate the secretion of the gonadotropic hormones luteinizing hormone (LH) and follicle-stimulating hormone (FSH). This receptor mediates its action by association with G-proteins that activate a phosphatidylinositol-calcium second messenger system. Isoform 2 may act as an inhibitor of GnRH-R signaling.
Similarity
Belongs to the G-protein coupled receptor 1 family.
Mass
37.731 kDa
Sequence
MANSASPEQNQNHCSAINNSIPLMQGNLPTLTLSGKIRVTVTFFLFLLSATFNASFLLKLQKWTQKKEKGKKLSRMKLLLKHLTLANLLETLIVMPLDGMWNITVQWYAGELLCKVLSYLKLFSMYAPAFMMVVISLDRSLAITRPLALKSNSKVGQSMVGLAWILSSVFAGPQLYIFRMIHLADSSGQTKVFSQCVTHCSFSQWWHQAFYNFFTFSCLFIIPLFIMLICNAKIIFTLTRVLHQDPHELQLNQSKNNIPRARLKTLKMTVAFATSFTVCWTPYYVLGIWYWFDPEMLNRLSDPVNHFFFLFAFLNPCFDPLIYGYFSL

Gene
GNRHR
Protein
Gonadotropin-releasing hormone receptor
Organism
Sus scrofa
Length
328 amino acids
Function
Receptor for gonadotropin releasing hormone (GnRH) that mediates the action of GnRH to stimulate the secretion of the gonadotropic hormones luteinizing hormone (LH) and follicle-stimulating hormone (FSH). This receptor mediates its action by association with G-proteins that activate a phosphatidylinositol-calcium second messenger system.
Similarity
Belongs to the G-protein coupled receptor 1 family.
Mass
37.747 kDa
Sequence
MANSASPEQNQNHCSAINSSILLTQGNLPTLTLSGKIRVTVTFFLFLLSTAFNASFLLKLQKWTQRKEKGKKLSRMKVLLKHLTLANLLETLIVMPLDGMWNITVQWYAGEFLCKVLSYLKLFSMYAPAFMMVVISLDRSLAITRPLAVKSNSRLGRFMIGLAWLLSSIFAGPQLYIFRMIHLADSSGQTEGFSQCVTHGSFPQWWHQAFYNFFTFSCLFIIPLLIMLICNAKIMFTLTRVLQQDPHNLQLNQSKNNIPRARLRTLKMTVAFAASFIVCWTPYYVLGIWYWFDPEMVNRVSDPVNHFFFLFAFLNPCFDPLIYGYFSL

Gene
GNRHR
Protein
Gonadotropin-releasing hormone receptor
Organism
Canis lupus familiaris
Length
327 amino acids
Function
Receptor for gonadotropin releasing hormone (GnRH) that mediates the action of GnRH to stimulate the secretion of the gonadotropic hormones luteinizing hormone (LH) and follicle-stimulating hormone (FSH). This receptor mediates its action by association with G-proteins that activate a phosphatidylinositol-calcium second messenger system.
Similarity
Belongs to the G-protein coupled receptor 1 family.
Mass
37.656 kDa
Sequence
MASASPEQNQNHCSAVNNSNMLMQGNLPTLTLSGKIRVTVTFFLFLLSTIFNASFLLKLQKWTQKKEKGKKLSRMKVLLKHLTLANLLETLIVMPLDGMWNITVQWYAGEFLCKVLSYLKLFSMYAPAFMMVVISLDRSLAITRPLAMKNNGKLGQSMIGLAWLLSGIFAGPQLYIFRMIHLADSSGQTEGFPQCVTHCSFPQWWHQAFYNFFTFSCLFIIPLFITLICNAKIIFTLTRVLHQDPHELQLNQSKNNIPRARLRTLKMTVAFATSFTVCWTPYYVLGIWYWFDPEMLNRVSDPVNHFFFLFALLNPCFDPLIYGYFSL

Gene
Gnrhr
Protein
Gonadotropin-releasing hormone receptor
Organism
Mus musculus
Length
327 amino acids
Function
Receptor for gonadotropin releasing hormone (GnRH) that mediates the action of GnRH to stimulate the secretion of the gonadotropic hormones luteinizing hormone (LH) and follicle-stimulating hormone (FSH). This receptor mediates its action by association with G-proteins that activate a phosphatidylinositol-calcium second messenger system.
Similarity
Belongs to the G-protein coupled receptor 1 family.
Mass
37.684 kDa
Sequence
MANNASLEQDPNHCSAINNSIPLIQGKLPTLTVSGKIRVTVTFFLFLLSTAFNASFLLKLQKWTQKRKKGKKLSRMKVLLKHLTLANLLETLIVMPLDGMWNITVQWYAGEFLCKVLSYLKLFSMYAPAFMMVVISLDRSLAITQPLAVQSNSKLEQSMISLAWILSIVFAGPQLYIFRMIYLADGSGPTVFSQCVTHCSFPQWWHQAFYNFFTFGCLFIIPLLIMLICNAKIIFALTRVLHQDPRKLQLNQSKNNIPRARLRTLKMTVAFATSFVVCWTPYYVLGIWYWFDPEMLNRVSEPVNHFFFLFAFLNPCFDPLIYGYFSL

Gene
Gnrhr
Protein
Gonadotropin-releasing hormone receptor
Organism
Rattus norvegicus
Length
327 amino acids
Function
Receptor for gonadotropin releasing hormone (GnRH) that mediates the action of GnRH to stimulate the secretion of the gonadotropic hormones luteinizing hormone (LH) and follicle-stimulating hormone (FSH). This receptor mediates its action by association with G-proteins that activate a phosphatidylinositol-calcium second messenger system.
Similarity
Belongs to the G-protein coupled receptor 1 family.
Mass
37.748 kDa
Sequence
MANNASLEQDQNHCSAINNSIPLTQGKLPTLTLSGKIRVTVTFFLFLLSTAFNASFLVKLQRWTQKRKKGKKLSRMKVLLKHLTLANLLETLIVMPLDGMWNITVQWYAGEFLCKVLSYLKLFSMYAPAFMMVVISLDRSLAVTQPLAVQSKSKLERSMTSLAWILSIVFAGPQLYIFRMIYLADGSGPAVFSQCVTHCSFPQWWHEAFYNFFTFSCLFIIPLLIMLICNAKIIFALTRVLHQDPRKLQLNQSKNNIPRARLRTLKMTVAFGTSFVICWTPYYVLGIWYWFDPEMLNRVSEPVNHFFFLFAFLNPCFDPLIYGYFSL

Gene
GNRHR
Protein
Gonadotropin-releasing hormone receptor
Organism
Macaca mulatta
Length
59 amino acids
Function
Receptor for gonadotropin releasing hormone (GnRH) that mediates the action of GnRH to stimulate the secretion of the gonadotropic hormones luteinizing hormone (LH) and follicle-stimulating hormone (FSH). This receptor mediates its action by association with G-proteins that activate a phosphatidylinositol-calcium second messenger system.
Similarity
Belongs to the G-protein coupled receptor 1 family.
Mass
7.09 kDa
Fragment
single
Sequence
VAFATSFTVCWTPYYVLGIWYWFDPEMLNRVSDPVNHFFFLFAFLNPCFDPLIYGYFSL