About Products Protein Database Contact

GNPTG

Gene
Gnptg
Protein
N-acetylglucosamine-1-phosphotransferase subunit gamma
Organism
Mus musculus
Length
307 amino acids
Function
Non-catalytic subunit of the N-acetylglucosamine-1-phosphotransferase complex, an enzyme that catalyzes the formation of mannose 6-phosphate (M6P) markers on high mannose type oligosaccharides in the Golgi apparatus. Binds and presents the high mannose glycans of the acceptor to the catalytic alpha and beta subunits (GNPTAB). Enhances the rate of N-acetylglucosamine-1-phosphate transfer to the oligosaccharides of acid hydrolase acceptors.
Mass
34.169 kDa
Sequence
MAGRLAGFLMLLGLASQGPAPAYAGKMKVVEEPNTFGLNNPFLPQASRLQPKREPSAVSGPLHLFRLAGKCFSLVESTYKYEFCPFHNVTQHEQTFRWNAYSGILGIWHEWEIINNTFKGMWMTDGDSCHSRSRQSKVELTCGKINRLAHVSEPSTCVYALTFETPLVCHPHSLLVYPTLSEALQQRWDQVEQDLADELITPQGYEKLLRVLFEDAGYLKVPGETHPTQLAGGSKGLGLETLDNCRKAHAELSQEVQRLTSLLQQHGIPHTQPTETTHSQHLGQQLPIGAIAAEHLRSDPGLRGNIL

Gene
GNPTG
Protein
N-acetylglucosamine-1-phosphotransferase subunit gamma
Organism
Bos taurus
Length
306 amino acids
Function
Non-catalytic subunit of the N-acetylglucosamine-1-phosphotransferase complex, an enzyme that catalyzes the formation of mannose 6-phosphate (M6P) markers on high mannose type oligosaccharides in the Golgi apparatus. Binds and presents the high mannose glycans of the acceptor to the catalytic alpha and beta subunits (GNPTAB). Enhances the rate of N-acetylglucosamine-1-phosphate transfer to the oligosaccharides of acid hydrolase acceptors (By similarity).
Mass
33.783 kDa
Sequence
MAARLAGLAVVLGFAARGPAPGGAAKMKVVEEPNTFGLNNPFLPQTSRLQPKRDPSPVSGPAHLSRLSGKCFSLVESTYKYELCPFHNVTQHEQTFRWNAYSGILGIWHEWEITNNTFRGMWMRDGDACQSRSRQSKVELTCGKSNRLAHVSEPSTCVYALTFETPLVCHPHSLLVYPTLPAALQQRWDQLEQDLVDELITAQGYEKSLRAIFEDAGYLKTSEPNEAAQQEGGTKGLRFETLESCQEAHKALSQEIKRLQGVLTQHGVPYGKPTETPSSEHWGPQVPTAGMAEPLRGDPGLRGDTL

Gene
GNPTG
Protein
N-acetylglucosamine-1-phosphotransferase subunit gamma
Organism
Homo sapiens
Length
305 amino acids
Function
Non-catalytic subunit of the N-acetylglucosamine-1-phosphotransferase complex, an enzyme that catalyzes the formation of mannose 6-phosphate (M6P) markers on high mannose type oligosaccharides in the Golgi apparatus. Binds and presents the high mannose glycans of the acceptor to the catalytic alpha and beta subunits (GNPTAB). Enhances the rate of N-acetylglucosamine-1-phosphate transfer to the oligosaccharides of acid hydrolase acceptors.
Mass
33.974 kDa
Sequence
MAAGLARLLLLLGLSAGGPAPAGAAKMKVVEEPNAFGVNNPFLPQASRLQAKRDPSPVSGPVHLFRLSGKCFSLVESTYKYEFCPFHNVTQHEQTFRWNAYSGILGIWHEWEIANNTFTGMWMRDGDACRSRSRQSKVELACGKSNRLAHVSEPSTCVYALTFETPLVCHPHALLVYPTLPEALQRQWDQVEQDLADELITPQGHEKLLRTLFEDAGYLKTPEENEPTQLEGGPDSLGFETLENCRKAHKELSKEIKRLKGLLTQHGIPYTRPTETSNLEHLGHETPRAKSPEQLRGDPGLRGSL