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GLYAT

Gene
GLYAT
Protein
Glycine N-acyltransferase
Organism
Homo sapiens
Length
296 amino acids
Function
Mitochondrial acyltransferase which transfers an acyl group to the N-terminus of glycine and glutamine, although much less efficiently. Can conjugate numerous substrates to form a variety of N-acylglycines, with a preference for benzoyl-CoA over phenylacetyl-CoA as acyl donors. Thereby detoxify xenobiotics, such as benzoic acid or salicylic acid, and endogenous organic acids, such as isovaleric acid.
Similarity
Belongs to the glycine N-acyltransferase family.
Mass
33.924 kDa
Sequence
MMLPLQGAQMLQMLEKSLRKSLPASLKVYGTVFHINHGNPFNLKAVVDKWPDFNTVVVCPQEQDMTDDLDHYTNTYQIYSKDPQNCQEFLGSPELINWKQHLQIQSSQPSLNEAIQNLAAIKSFKVKQTQRILYMAAETAKELTPFLLKSKILSPNGGKPKAINQEMFKLSSMDVTHAHLVNKFWHFGGNERSQRFIERCIQTFPTCCLLGPEGTPVCWDLMDQTGEMRMAGTLPEYRLHGLVTYVIYSHAQKLGKLGFPVYSHVDYSNEAMQKMSYTLQHVPIPRSWNQWNCVPL

Gene
Glyat
Protein
Glycine N-acyltransferase
Organism
Mus musculus
Length
296 amino acids
Function
Mitochondrial acyltransferase which transfers an acyl group to the N-terminus of glycine and glutamine, although much less efficiently. Can conjugate a multitude of substrates to form a variety of N-acylglycines, thereby detoxify xenobiotics, such as benzoic acid or salicylic acid, and endogenous organic acids, such as isovaleric acid.
Similarity
Belongs to the glycine N-acyltransferase family.
Mass
34.098 kDa
Sequence
MIVPLQGAQMLQMLEKSLRKYLPESLKVYGTVYHMIHGNPFNLKALVDKWPDFNTVVVRPQEQEMTDDLDFYINTYQVYSKDPQNCQEFLESSEVINWKQHLQIQSSQSHLNKTIQNLASIQSFQIKHSENILYVSSETIKKLFPSLLDTKNLSTGSGKPKAIDQDKFKLSSLDVVHAALVNKFWLFGGNERSQRFIERCIKNFPSSCVLGPEGTPASWTLMDQTGEMRMGGTMPEYRLQGLVSFVVHSQDQIMTKRGYPVYSHTEKSNIAMQKMSYTLQHLPMPCAWNQWKCMPM

Gene
GLYAT
Protein
Glycine N-acyltransferase
Organism
Pongo abelii
Length
296 amino acids
Function
Mitochondrial acyltransferase which transfers an acyl group to the N-terminus of glycine and glutamine, although much less efficiently. Can conjugate a multitude of substrates to form a variety of N-acylglycines, thereby detoxify xenobiotics, such as benzoic acid or salicylic acid, and endogenous organic acids, such as isovaleric acid.
Similarity
Belongs to the glycine N-acyltransferase family.
Mass
33.855 kDa
Sequence
MMLPLQGAQMLQVLEKSLRRSLPASLKVYGTVFHINHGNPFNLKAVVDKWPDFNTVVVCPQEQDMTDDLDHYTNTYQIYSKDPQNCQEFLGSPELINWKQHLQIQSSQPSLNEAIQNLAVIKSFKVKQTQRILYMAAETAKELAPFLLKSKILSPSGGKPKAINQEMFKLSSMDVTHAQLVSKFWHFGGNERSQRFIERCIQTFPTCCLLGPEGTPVCWDLMDQTGEMRMAGTLPEYRLHGLVTYVIYSHAQKLGKLGFPVYSHVDYSNEAMQKMSYTLQHVPIPRSWNQWNCVPL

Gene
Glyat
Protein
Glycine N-acyltransferase
Organism
Rattus norvegicus
Length
296 amino acids
Function
Mitochondrial acyltransferase which transfers an acyl group to the N-terminus of glycine and glutamine, although much less efficiently. Can conjugate a multitude of substrates to form a variety of N-acylglycines, thereby detoxify xenobiotics, such as benzoic acid or salicylic acid, and endogenous organic acids, such as isovaleric acid.
Similarity
Belongs to the glycine N-acyltransferase family.
Mass
33.899 kDa
Sequence
MIVPLQGAQMLQMLEKSLKKYLPESLKVYGTIYHVNHGNPFNLKALVDKWPDFNTVVVRPQEQEMKDDLDFYTNTYQIYSKDPENCQEFLGSSEVINWKQHLQIQSSQSHLNKAIQNLASIHSLQVKHSENILYVVSETVRKLFPSLLDTKNLSPGSGKPKAINQEMFKLSSLDVTHAALVNKFWLFGGNERSQRFIERCIKNFPSSCVLGPEGTPASWTLMDQTGEMRMGGTVPQYRAQGLVSFVIYSQDQIMKKRGFPVYSHTDKSNTVMQKMSYSLQHLPMPCAWNQWICVPM

Gene
GLYAT
Protein
Glycine N-acyltransferase
Organism
Bos taurus
Length
295 amino acids
Function
Mitochondrial acyltransferase which transfers an acyl group to the N-terminus of glycine and glutamine, although much less efficiently. Can conjugate a multitude of substrates to form a variety of N-acylglycines, thereby detoxify xenobiotics, such as benzoic acid or salicylic acid, and endogenous organic acids, such as isovaleric acid.
Similarity
Belongs to the glycine N-acyltransferase family.
Mass
33.907 kDa
Sequence
MFLLQGAQMLQMLEKSLRKSLPMSLKVYGTVMHMNHGNPFNLKALVDKWPDFQTVVIRPQEQDMKDDLDHYTNTYHVYSEDLKNCQEFLDLPEVINWKQHLQIQSTQSSLNEVIQNLAATKSFKVKRSKNILYMASETIKELTPSLLDVKNLPVGDGKPKAIDPEMFKLSSVDPSHAAVVNRFWLFGGNERSLRFIERCIQSFPNFCLLGTEGTPVSWSLMDQTGEMRMAGTLPEYRAQGLVTHAIYQQAQCLLKRGFPVYSHVDPKNQIMQKMSQSLNHVPMPSDWNQWNCEPL