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GGACT

Gene
GGACT
Protein
Gamma-glutamylaminecyclotransferase
Organism
Bos taurus
Length
168 amino acids
Function
Contributes to degradation of proteins cross-linked by transglutaminases by degrading the cross-link between a lysine and a glutamic acid residue. Catalyzes the formation of 5-oxo-L-proline from L-gamma-glutamyl-L-epsilon-lysine. Inactive with L-gamma-glutamyl-alpha-amino acid substrates such as L-gamma-glutamyl-L-alpha-cysteine and L-gamma-glutamyl-L-alpha-alanine.
Similarity
Belongs to the gamma-glutamylcyclotransferase family.
Mass
19.052 kDa
Sequence
MPGPECKWSTTETGAPCGTDDSSGRLAPVFVYGTLKTGQPNHRVLLDGAHGRAAFRGRAHTLEPYPLVIAGEHNIPRLLNLPGRGHRVFGEVYEVDERMLRFLDEFESCPDMYQRTRLHVALEGVRGPLECFVYTTATYPPEWVHLPYLDDYDSQGKHGLRYNPRENR

Gene
GGACT
Protein
Gamma-glutamylaminecyclotransferase
Organism
Homo sapiens
Length
153 amino acids
Function
Contributes to degradation of proteins cross-linked by transglutaminases by degrading the cross-link between a lysine and a glutamic acid residue. Catalyzes the formation of 5-oxo-L-proline from L-gamma-glutamyl-L-epsilon-lysine. Inactive with L-gamma-glutamyl-alpha-amino acid substrates such as L-gamma-glutamyl-L-alpha-cysteine and L-gamma-glutamyl-L-alpha-alanine.
Similarity
Belongs to the gamma-glutamylcyclotransferase family.
Mass
17.329 kDa
Sequence
MALVFVYGTLKRGQPNHRVLRDGAHGSAAFRARGRTLEPYPLVIAGEHNIPWLLHLPGSGRLVEGEVYAVDERMLRFLDDFESCPALYQRTVLRVQLLEDRAPGAEEPPAPTAVQCFVYSRATFPPEWAQLPHHDSYDSEGPHGLRYNPRENR

Gene
Ggact
Protein
Gamma-glutamylaminecyclotransferase
Organism
Mus musculus
Length
149 amino acids
Function
Contributes to degradation of proteins cross-linked by transglutaminases by degrading the cross-link between a lysine and a glutamic acid residue. Catalyzes the formation of 5-oxo-L-proline from L-gamma-glutamyl-L-epsilon-lysine. Inactive with L-gamma-glutamyl-alpha-amino acid substrates such as L-gamma-glutamyl-L-alpha-cysteine and L-gamma-glutamyl-L-alpha-alanine.
Similarity
Belongs to the gamma-glutamylcyclotransferase family.
Mass
17.08 kDa
Sequence
MAHIFVYGTLKRGQPNHKVMLDHSHGLAAFRGRGCTVESFPLVIAGEHNIPWLLYLPGKGHCVTGEIYEVDEQMLRFLDDFEDCPSMYQRTALQVQVLEWEGDGDPGDSVQCFVYTTATYAPEWLFLPYHESYDSEGPHGLRYNPRENR

Gene
Ggact
Protein
Gamma-glutamylaminecyclotransferase
Organism
Rattus norvegicus
Length
149 amino acids
Function
Contributes to degradation of proteins cross-linked by transglutaminases by degrading the cross-link between a lysine and a glutamic acid residue. Catalyzes the formation of 5-oxo-L-proline from L-gamma-glutamyl-L-epsilon-lysine. Inactive with L-gamma-glutamyl-alpha-amino acid substrates such as L-gamma-glutamyl-L-alpha-cysteine and L-gamma-glutamyl-L-alpha-alanine.
Similarity
Belongs to the gamma-glutamylcyclotransferase family.
Mass
16.925 kDa
Sequence
MAHIFVYGTLKRGQPNHKVMLDQSHGLATFRGRGCTVESFPLVIAGEHNIPWLLHLPGKGHCVAGEIYEVDEQMLRFLDDFEGCPSMYQRTALQVRVLEWEGAGGPGDSVQCFVYSTATYAPEWLFLPYHKNYDSEGPHGLRYNPRENR

Gene
ggact
Protein
Gamma-glutamylaminecyclotransferase
Organism
Xenopus laevis
Length
138 amino acids
Function
May contribute to degradation of proteins cross-linked by transglutaminases by degrading the cross-link between a lysine and a glutamic acid residue. Catalyzes the formation of 5-oxo-L-proline from L-gamma-glutamyl-L-epsilon-lysine.
Similarity
Belongs to the gamma-glutamylcyclotransferase family.
Mass
16.062 kDa
Sequence
MTCYKHGKAVFKGMGKTVEKYPLVIAEEANIPFLLNIPGTGRRIIGEIYSVDEQLLHFLDDFEGCPNWYQRTPQEIEILEWEGTDDSPDERPAANSIITCFVYSTTCYQPEWLQLPYHKCYDAFGNHGLRYIRHRDII