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GG14034

Gene
GG14034
Protein
Queuine tRNA-ribosyltransferase accessory subunit 2
Organism
Drosophila erecta
Length
418 amino acids
Function
Non-catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
Similarity
Belongs to the queuine tRNA-ribosyltransferase family. QTRT2 subfamily.
Mass
46.519 kDa
Sequence
MKFAIESISKNSGRLGQLRIKDGGPELKTPLLLQTTKGGSIPWLSADVFESHVSQKPQVLQFTLSTMDQMTEALTHWNSGGGNGLSGYVGLPGHLNILMVRDPCETTLSGGNDRDIMPLFTRRGKESLSSERYMEMVASFKPDIYQGLCDADTNLDSAKKRIQKSVDRTEKFMHYIYEHRCKVNSTLLAPIVGGYNTFARTQSIKHAREQPAGSYGGYIFEGFHTNGLTATTLDTSKLLPIVEHCVKQLEEDKPRILPGAYTPLTILELIRQGIDVFDSSYAYCASLNFKALTFSFVQDAVEHVPFLDITDEAIKEDFTPPLSECSCLTCQKHTRAYLHHLYKTNELLGPILLMVHNIHHYMAFFEEIRESVAKDALPQLTELVRNQNGKTQVDYSIAANNKVISKATMGKGFAAAAV