GEX2

Protein GAMETE EXPRESSED 2

914 amino acids

100.588 kDa

MVGIFNIVIDEENFKVLDSSLHFEVEAGLMYPSVSVVSWMGLANVFEAGMNASILILPKDAFGNNISFSGKKMEFQEFSLSLISENGSFAGVLNSTHIRWIVSGYISIDFVLVTSGKFLLLVEKESQTLNGGPLPLEVNSGPLDVSNCVSIWKSELSTWQIFSKMEILLHQKDRFGNIVSGFYEFDADVVEVETGLSIPVADFQFEYVEPGIQLMSFTLSEPGNFLLTLSDMKHNKSISSMPYVYTVYIGYCDGSRSIVNGSGINASIAGESLGFSVYLKDAYGYPSPVQVDRLQVRIVLEIDSSIILPTIQPREALNGTGSSHQAATPLYEKHGGRASGNLVTQASIFDVTYTPKRTGIYRIFISSGNIVLNGGQPFIKEVYAGEVNVAACSVTQFNGKVPKEIKNEIVVLLLDGFYNPVPSQPSRLKFEITSANTSSFTTWEFVDNNDGTYTGSYLAMEVGTYRMCISFDNKHIQPCPFDVNVYSNGYFPRAYDDPVNVWEDESISFNPLENDYFAGDNASMLGFSQPGHGSLLRDGNLLRYTPMKNFSGNDSFLYTIADINGNLAAATVYIFVLTAPPQFVSFSGGLQATEDLISPRYGGFSGLEISYSDLLENISVMVQALSGSVILSPMLMQFRPPGSGKLSVSNGGEDRRVLILEGQVGVINPALQSIQYLGNENFAGVDSLRLSTKNKNGINHLDVPVFVEPVNDPPFINVPQYIMLESNGSESLIFHPERDKFNFSVGDPDLVNFPGGESHFLVTFSLEVTDGFLLTNLPSELINSTELKFKNLFQWQPIQTYAAISKHVNVKASGIRFRGTIRQCNDLMQQLLHRGGENGAVLTLKLSDMGNYGCFLDCTERISLPLHAEARVNLIRKRPLSSLGAHGTFMKYLVVVPFSFFSIKLFSLLMVLIG

GEX2

Glutathione exchanger 2

615 amino acids

Proton/glutathione antiporter that imports glutathione from the vacuole and exports it through the plasma membrane. Involved in resistance to oxidative stress and modulation of the PKA pathway.

Belongs to the major facilitator superfamily.

68.954 kDa

MSSSVVGASSNKKSGIRQSCEIIERERHSNDDTYSMTSTFFKLKENEIMSAQFDSLKYKILLISTAFVCGFGISLDYTLRSTYTGYATNSYSEHSLLSTVQVINAVVSVGSQVVYSRLSDHFGRLRLFLVATIFYIMGTIIQSQATRLTMYAAGSVFYNCGYVGTNLLLTLILSDFSSLKWRMFYQYASYWPYIIIPWISGNIITAANPQKNWSWNIAMWAFIYPLSTLPIIFLILYMKYKSSKTAEWRSLKEQARKERTGGLFENLVFLFWKLDIVGILLITVSLGCILVPLTLANETSQKWHNSKIIATLVSGGCLFFIFLYWEAKFAKSPLLPFKLLSDRGIWAPLGVTFFNFFTFFISCDYLYPVLLVSMKESSTSAARIVNLPDFVAATASPFYSLLVAKTRKLKLSVIGGCAAWMVCMGLFYKYRGGSGSHEGVIAASVIMGLSGLLCSNSVIVILQAMTTHSRMAVITGIQYTFSKLGAAIGASVSGAIWTQTMPNQLYKNLGNDTLAEIAYASPYTFISDYPWGSPERDAVVESYRYVQRIIMTVGLACTVPFFTFTMFMRNPELIDKATHEEFTEDGLVVLPDEENIFSQIKALFRHNRSNKKSGC