GDPD3

Gene

GDPD3

Protein

Glycerophosphodiester phosphodiesterase GDPD3

Organism

Arabidopsis thaliana

Length

370 amino acids

Similarity

Belongs to the glycerophosphoryl diester phosphodiesterase family.

Mass

42.293 kDa

Sequence

MALETMTLSLSSSAMLSSGVVEDDKKQEAIVFPKFVLMGHRGFGMNMLQSPDEKMKFIKENSLLSFNVAADFPIDFIEFDVQVTRDGCPVIFHDIFMFTQEQGVIIEKRVTEMDLHEFLSYGPQRDGTNVKPMWRKTKDGRIFEWKVEKDDPLCTLEDAFLNVKHSLGFNIELKFDDNTVYGEGELRQTLDNILTVVNEHSKNRPIIFSSFHPDAARLIRNMQRCYPVFFLTNGGCEIYKDVRRNSLDEAIKLCKESGLQGLVSEVKAILRTPNAITRVKDSKLSLLSYGQLNNVVEVIYLQYLMGVEGVIVDMVKDISEAIANIEVTNEDDCEGEDERKCLIRFGEERKKVEITKDMITLLNKFVPKLL

Protein

Glycerophosphodiester phosphodiesterase GDPD3: GDPD3

Gene

Gdpd3

Protein

Lysophospholipase D GDPD3

Organism

Mus musculus

Length

330 amino acids

Function

Hydrolyzes lysoglycerophospholipids to produce lysophosphatidic acid (LPA) and the corresponding amines (PubMed:25528375). Shows a preference for 1-O-alkyl-sn-glycero-3-phosphocholine (lyso-PAF) and lysophosphatidylcholine (lyso-PC), and to a lesser extent for lysophosphatidylethanolamine (lyso-PE) (PubMed:25528375). Does not display glycerophosphodiester phosphodiesterase activity, since it cannot hydrolyze either glycerophosphoinositol or glycerophosphocholine (PubMed:25528375).

Similarity

Belongs to the glycerophosphoryl diester phosphodiesterase family.

Mass

38.488 kDa

Sequence

MIPLLYFVLPTLGSYVMLSIFFLRRPHLLHTPRAPVFPIRLAAHRGGSGERLENTMEAVENSMAQRADLLEFDCQLTRDGVVVVSHDKNLSRQSGLNKDVNTLDFEELPLYKEELEIYFSPGHFAHGSDRHMISLEDVFQKFPRTPMCLEVKERNEELIHKVANLTRRFDRNEITIWAAEKSSVMKRCRAANPEMPMAFTIWRSFWILLLYYLGLLPFVSIPEKFFFCFLPTIINRTYFPFRCGWMNQLSATITKWIIMRKSLIRHLQDRGVQVLFWCLNEESDFEVAFSLGANGVMTDYPTALRHYLDKQEEETQPPQPEALSCLSLKK

Protein

Lysophospholipase D GDPD3: Gdpd3

Gene

GDPD3

Protein

Lysophospholipase D GDPD3

Organism

Homo sapiens

Length

318 amino acids

Function

Hydrolyzes lysoglycerophospholipids to produce lysophosphatidic acid (LPA) and the corresponding amines. Shows a preference for 1-O-alkyl-sn-glycero-3-phosphocholine (lyso-PAF) and lysophosphatidylcholine (lyso-PC), and to a lesser extent for lysophosphatidylethanolamine (lyso-PE). Does not display glycerophosphodiester phosphodiesterase activity, since it cannot hydrolyze either glycerophosphoinositol or glycerophosphocholine.

Similarity

Belongs to the glycerophosphoryl diester phosphodiesterase family.

Mass

36.596 kDa

Sequence

MSLLLYYALPALGSYAMLSIFFLRRPHLLHTPRAPTFRIRLGAHRGGSGELLENTMEAMENSMAQRSDLLELDCQLTRDRVVVVSHDENLCRQSGLNRDVGSLDFEDLPLYKEKLEVYFSPGHFAHGSDRRMVRLEDLFQRFPRTPMSVEIKGKNEELIREIAGLVRRYDRNEITIWASEKSSVMKKCKAANPEMPLSFTISRGFWVLLSYYLGLLPFIPIPEKFFFCFLPNIINRTYFPFSCSCLNQLLAVVSKWLIMRKSLIRHLEERGVQVVFWCLNEESDFEAAFSVGATGVITDYPTALRHYLDNHGPAARTS

Protein

Lysophospholipase D GDPD3: GDPD3