gdh2

Probable NAD-specific glutamate dehydrogenase

1106 amino acids

NAD(+)-dependent glutamate dehydrogenase which degrades glutamate to ammonia and alpha-ketoglutarate.

Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

125.712 kDa

MYLTKQIPHYSRIHTTQLLTVVNHRTIPFKIRGSFSNCRRYSNFATVPLLERPFKNKSKHNTARASRPFSTQKMLLTKSHPPNMYKDSVFFGYRPIVFSGKQDQKSKVIQCLRTERKTIPDDLVEDEVDRFYNKLGLDDYYFQMEPVSIIADHIEIIYAAKIAAHASHAKEELNIHVKNENEDLAIYLDSSPVTQPELDQSSAVEESISTRYLDPFKLTDPTAYRVESFTSVTNIDRTSTENSNIYTYFVTKCDFVDNPKKDASPDVPTDIASVSDKTFLEKASDNTIEMYQDVMNSVLTRFGPVVRLFDYQGRSEIRLVVGYRRGSIFQYFPSLSKLFRYYGLHSTRTYVEQFSNGVTIISYNFKPELFKNAAVTSINELFSQITREASLLYCLPSTDFQPLFVSEKLSIQEVTYAHCVRIFCEHVMNKLGPEYSSLSAILDHSNNIHAEILETIKRRLSTLAFTRTKIHDTIMQYPGLVHTLFEQFYLEHAINHNSTPHLHRAKSATSLADEASTYSITPMSATALMDLIQKTCTNEEDVSVMEMFVKFNTHLLKTNFFQTTKVALSFRFDPSFLDSTQYKDPLYAMIMSIGNEFRGFHLRFRDVARGGIRLIKSANPEAFGLNARGLFDENYNLAKTQMLKNKDIPEGGAKGVILLGKDCQDKPELAFMKYIDSIIDLLIVNKSQPLVDKLGKPEILFMGPDENTADLVNWATIHAHRRNAPWWKSFFTGKKPTMGGIPHDKYGMTSLSVRCYVEGIYKKLNITDPSKLTKVQTGGPDGDLGSNEIKLSNEKYIAVIDGSGVLYDPAGLDRTELLRLADERKTIDHFDAGKLSPEGYRVLVKDTNLKLPNGEIVRNGTIFRNTAHLRYKADTFVPCGGRPNAININNVEQLIDDHGRPAFKYLVEGANLFITQDAKSVLEKAGVIVIRDASANKGGVTSSSLEVLASLSFDDASFKENMCVHDGKVPTFYADYVNEVKRIIQRNANLEFEAIWKGHSENKIPYTSLSNHLSTEIVKLDHDIYNYEKLWADVGFRNAVLRASIPKTLQAKIGLEKMLERIPESYLRAIFSTYLASRFVYQHVVSSDPFAFFDYISTEMKMLKDA

GDH2

NAD-specific glutamate dehydrogenase

1092 amino acids

NAD(+)-dependent glutamate dehydrogenase which degrades glutamate to ammonia and alpha-ketoglutarate.

Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

124.332 kDa

MLFDNKNRGALNSLNTPDIASLSISSMSDYHVFDFPGKDLQREEVIDLLDQQGFIPDDLIEQEVDWFYNSLGIDDLFFSRESPQLISNIIHSLYASKLDFFAKSKFNGIQPRLFSIKNKIITNDNHAIFMESNTGVSISDSQQKNFKFASDAVGNDTLEHGKDTIKKNRIEMDDSCPPYELDSEIDDLFLDNKSQKNCRLVSFWAPESELKLTFVYESVYPNDDPAGVDISSQDLLKGDIESISDKTMYKVSSNENKKLYGLLLKLVKEREGPVIKTTRSVENKDEIRLLVAYKRFTTKRYYSALNSLFHYYKLKPSKFYLESFNVKDDDIIIFSVYLNENQQLEDVLLHDVEAALKQVEREASLLYAIPNNSFHEVYQRRQFSPKEAIYAHIGAIFINHFVNRLGSDYQNLLSQITIKRNDTTLLEIVENLKRKLRNETLTQQTIINIMSKHYTIISKLYKNFAQIHYYHNSTKDMEKTLSFQRLEKVEPFKNDQEFEAYLNKFIPNDSPDLLILKTLNIFNKSILKTNFFITRKVAISFRLDPSLVMTKFEYPETPYGIFFVVGNTFKGFHIRFRDIARGGIRIVCSRNQDIYDLNSKNVIDENYQLASTQQRKNKDIPEGGSKGVILLNPGLVEHDQTFVAFSQYVDAMIDILINDPLKENYVNLLPKEEILFFGPDEGTAGFVDWATNHARVRNCPWWKSFLTGKSPSLGGIPHDEYGMTSLGVRAYVNKIYETLNLTNSTVYKFQTGGPDGDLGSNEILLSSPNECYLAILDGSGVLCDPKGLDKDELCRLAHERKMISDFDTSKLSNNGFFVSVDAMDIMLPNGTIVANGTTFRNTFHTQIFKFVDHVDIFVPCGGRPNSITLNNLHYFVDEKTGKCKIPYIVEGANLFITQPAKNALEEHGCILFKDASANKGGVTSSSMEVLASLALNDNDFVHKFIGDVSGERSALYKSYVVEVQSRIQKNAELEFGQLWNLNQLNGTHISEISNQLSFTINKLNDDLVASQELWLNDLKLRNYLLLDKIIPKILIDVAGPQSVLENIPESYLKVLLSSYLSSTFVYQNGIDVNIGKFLEFIGGLKREAEASA

GDH2

NADP-specific glutamate dehydrogenase

451 amino acids

Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

48.826 kDa

MSHLPQEPEFEQAYGELASALENSSLFNEHPEYRTALAVAAIPERVIQFRVVWNDDKGNLQVNRGYRVQFNGALGPYKGGLRFHPSVNLSILKFLGFEQIFKNALTGLNMGGGKGGADFDPKGKSDAEIRRFCQAFMTELSKHIGAETDVPAGDIGVGGREIGYLFGAYRKFANRWEGVLTGKGLSWGGSLIRPEATGYGLVYYVEYMLKHANRGTFEGKRVALSGSGNVAQYAALKIIELGGSVVSLSDSKGALVAKEGSSFTPEQIHNIAALKIKHQALTTFEHDGQFTWIEGARPWVHVGKVDIALPSATQNEVSKEEAQALVDAGAFIVAEGSNMGCTAEAIDVFEAHRKEKGAEALWYAPGKASNCGGVAVSGLEMAQNSQRIQWTEKEVDDRLKAIMKDAFVAGLETAQKYVEAKEGELPSLIAGSNIAGFIKVAEAMHDQGDWF

GDH2

Glutamate dehydrogenase 2

411 amino acids

Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

44.699 kDa

MNALAATNRNFRHASRILGLDSKIERSLMIPFREIKVECTIPKDDGTLVSYIGFRVQHDNARGPMKGGIRYHPEVDPDEVNALAQLMTWKTAVADIPYGGAKGGIGCSPRDLSLSELERLTRVFTQKIHDLIGIHTDVPAPDMGTNAQTMAWILDEYSKFHGHSPAVVTGKPIDLGGSLGREAATGRGVVFATEALLAEYGKSIQGLTFVIQGFGNVGTWAAKLIHEKGGKVVAVSDITGAIRNPEGIDINALIKHKDATGSLNDFNGGDAMNSDELLIHECDVLIPCALGGVLNKENAGDVKAKFIVEAANHPTDPDADEILSKKGVIILPDIYANAGGVTVSYFEWVQNIQGFMWEEEKVNLELQKYMTRAFHNIKTMCHTHSCNLRMGAFTLGVNRVARATQLRGWEA

GDH2

Glutamate dehydrogenase 2, mitochondrial

411 amino acids

Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

44.551 kDa

MNALAATSRNFRQAARLLGLDSKLEKSLLIPFREIKVECTIPKDDGTLASFIGFRVQHDNARGPMKGGIRYHPEVDPDEVNALAQLMTWKTAVAAIPYGGAKGGIGCAPGELSTSELERLTRVFTQKIHDLIGAHTDVPAPDMGTNSQTMAWILDEYSKFHGHSPAVVTGKPIDLGGSLGRDAATGRGVMYATEALLAEHGKSISGSTFVIQGFGNVGSWAARIIHEKGGKVIALGDVTGSIRNKNGLDIPALMKHRNEGGALKDFHDAEVMDSSELLVHECDVLIPCALGGVLNRENAPDVKAKFIIEAANHPTDPEADEILAKKGVTILPDIYANSGGVIVSYFEWVQNIQGFMWDEEKVNMELHKYMNNSFQHIKAMCKSHDCNLRMGAFTLGVNRVARATLLRGWEA

GDH2

Glutamate dehydrogenase 2, mitochondrial

411 amino acids

Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

44.551 kDa

MNALAATSRNFRQAARLLGLDSKLEKSLLIPFREIKVECTIPKDDGTLASFIGFRVQHDNARGPMKGGIRYHPEVDPDEVNALAQLMTWKTAVAAIPYGGAKGGIGCAPGELSTSELERLTRVFTQKIHDLIGAHTDVPAPDMGTNSQTMAWILDEYSKFHGHSPAVVTGKPIDLGGSLGRDAATGRGVMYATEALLAEHGKSISGSTFVIQGFGNVGSWAARIIHEKGGKVIALGDVTGSIRNKNGLDIPALMKHRNEGGALKDFHDAEVMDSSELLVHECDVLIPCALGGVLNRENAPDVKAKFIIEAANHPTDPEADEILAKKGVTILPDIYANSGGVIVSYFEWVQNIQGFMWDEEKVNMELHKYMNNSFQHIKAMCKSHDCNLRMGAFTLGVNRVARATLLRGWEA

gdh2

Glucose 1-dehydrogenase 2

368 amino acids

Catalyzes the NAD(P)(+)-dependent oxidation of D-glucose to D-gluconate via gluconolactone. Can utilize both NAD(+) and NADP(+) as electron acceptor. Is involved in the degradation of glucose through a non-phosphorylative variant of the Entner-Doudoroff pathway.

Belongs to the zinc-containing alcohol dehydrogenase family. Glucose 1-dehydrogenase subfamily.

40.89 kDa

MKAIVVKPPNPGVEIKDVKDDENKLSNIGLVKVKILENGICGTDREIVSGKRTSVKPPIGKDELILGHEAIGIVEVGGYGFKEGELVMPINKRGCGKCLNCLIGRPDFCETGEGLVAGTKGLDGFMREYLYDDPKYLVKIPPAIKDIAILAQPLADIEKSVESILTSQKRIPIWTCDDGTLNCRKALVVGTGPTGILFSLVLRTYGFQVWIANRRELLDNEKEILDEPRILFYNSAKGYESLVKDVDKFDLIIDTTGASASIIQELVPLLQINGVLGLFGFPRYDNFSLDYKIVQDFVINNRIIIGLDNGQKPHFQQALIHLASWKSLWPKTASKMITKIISINDEREVISSLREKLPGEIKVKIVWE

gdh2

Glucose 1-dehydrogenase 2

366 amino acids

Catalyzes the NAD(P)(+)-dependent oxidation of D-glucose to D-gluconate via gluconolactone. Can utilize both NAD(+) and NADP(+) as electron acceptor. Is involved in the degradation of glucose through a non-phosphorylative variant of the Entner-Doudoroff pathway.

Belongs to the zinc-containing alcohol dehydrogenase family. Glucose 1-dehydrogenase subfamily.

40.916 kDa

MKAIVVKPPKPGVEVRDLSQVIRHGSGTVKVRILENGICGSDREIVKGELTTARPPEGRDWLVLGHEALGIVEDSSDPRFKPGDLVMPINRRSYHGKCLNCLVGRPDFCEANEFVEAGMVGMDGFMVEYWYDDPKYLVKVPKDIADIAIVAQPLSDLEKSVEEILNVQRRFIWTCDDGTYNCRRSIVFGTGSTGILISLLLRTVGFEVYVANRRDPLESEAKITEEAGIIYYNYSKDGLDKLKSMGFDLVVDTTGASASLIGHEVEMLKPNGILGLFGFPSEGELTLRYDVIQRFIYKSNAIVGLINGQKPHFQQALAHLAQWKVVWPTVAKSLITRVVDVNNDKELLQVLNHKERGEIKVKIKWS

gdh2

Glucose/galactose 1-dehydrogenase

359 amino acids

Catalyzes the NAD(P)(+)-dependent oxidation of D-glucose to D-gluconate via gluconolactone. Is also significantly active with D-galactose as substrate, but not with D-xylose, L-arabinose, D-ribose, D-mannose, D-allose, D-glucosamine, 2-deoxy-D-glucose, or glucose-6-phosphate. Can utilize both NAD(+) and NADP(+) as electron acceptor, with a marked preference for NADP(+) (20-fold higher activity). Physiologically, may be involved in the degradation of both glucose and galactose through a non-phosphorylative variant of the Entner-Doudoroff pathway.

Belongs to the zinc-containing alcohol dehydrogenase family. Glucose 1-dehydrogenase subfamily.

40.463 kDa

MVRAIITNAPNGGVKIENVNINEPEHYEVKLRPVYTGLCGTDRGEVLGNLSFAYNEPGYNYLVLGHEAICQVIEASENPYKIKPGDYVVPVVRRPGKCVNCRIGREDDCSDGDKHEAGITGLHGFMRDYFYDEAKNLVKINDKNMVKVAVLTEPTKNVMKAFEVFDTVSKRSIFQGDDSTNLTKNCLIIGTGSEAFLYAFMAREYRFNVFMTNRHPVGEEKLSIISRINADFYDYTREDPLKGIDLLIDTSGDPGTIFRFVRKMNYNGVVILFGTNGRAPATSIDGEDIDYIIERNISLVGSVDGAKRHYLRAVEYLEKWNYSEGSVINRLITGVFEPEDVSIFTKKPENEIKSVIKWS

gdh2

Glucose 1-dehydrogenase 2

356 amino acids

Catalyzes the NAD(P)(+)-dependent oxidation of D-glucose to D-gluconate via gluconolactone. Can utilize both NAD(+) and NADP(+) as electron acceptor. Is involved in the degradation of glucose through a modified Entner-Doudoroff pathway.

Belongs to the zinc-containing alcohol dehydrogenase family. Glucose 1-dehydrogenase subfamily.

37.871 kDa

MRAVALFPDEPELRVIEKPKPTPENGEALIRTVAVGIDGSDRRIAAGEIGGDVPDGEDHLVIGHEAVGVVEEPNGTDLARGDVVAPLVRRPVGDGSRFAANGELDMAPPGSFHECGITGAHGYMSEFFTARPGYLVPIPESRAAYGFFVEPASLVEKALDQTEAARSGFDWRPSSAFVLGNGNLGLLALTRLETGDEFERTYCLGRRDRPDPTIDVIENVGGTYVDSRELSLDEFPAVHEPVDFAFETTGHPAHAVEAVDALAPNGVVTLQGIPGSSSTVEIDGGAFHTDLVVTNKAILGVVNARRSHFRAAAEWLAETPESVLDALVTGVYGPDEIDEAFADSAETIKTVVSFDR

gdh2

Glucose 1-dehydrogenase 2

348 amino acids

Catalyzes the NAD(P)(+)-dependent oxidation of D-glucose to D-gluconate via gluconolactone. Can utilize both NAD(+) and NADP(+) as electron acceptor. Is involved in the degradation of glucose through a non-phosphorylative variant of the Entner-Doudoroff pathway.

Belongs to the zinc-containing alcohol dehydrogenase family. Glucose 1-dehydrogenase subfamily.

37.449 kDa

MKAVTVIPGIPESLRLMDVSKPNPNKGQVLLKPIRVGVCGTDKEIIEGRYGKAPEGNQYLILGHEAVAEVVEIGDGVDNAGVGDIVVPTVRRPLNCDLPVDFCPVGHYLEHGIWGLHGHAAEYSVTDAKYLVKVPKEIVDVAVLTEPLSVVEKGIDMAMRIGQARFDWKPRTALVLGAGPVGLLATMVLRLMGLSTVTTATRPPDSLKAKLVKELGGTYVDSAVGQISGEFDIVVEATGSPQVINEGLGHIAPNGVYVLLGVYPSGGSLNNLGELMTSVVLNNKVIVGSVNAGIKHFEMALEHLRRAKDEFNNWPAKLITKRANLSNYQEAYTWTHDDIKTVLEIIQS

GDH2

Glycine cleavage system H protein 2, mitochondrial

156 amino acids

The glycine decarboxylase (GDC) or glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity).

Belongs to the GcvH family.

17.1 kDa

MACRLFWASRVASHLRISVAQRGFSSVVLKDLKYADSHEWVKIDGNKATFGITDHAQDHLGDVVYVELPDVGHSVSQGKSFGAVESVKATSDINSPVSGKVVEVNEELTESPGLVNSSPYEQGWIIKVELSDAGEAEKLMDSDKYSKFCEEEDAKH