About Products Protein Database Contact

GBGT1

Gene
GBGT1
Protein
Globoside alpha-1,3-N-acetylgalactosaminyltransferase 1
Organism
Canis lupus familiaris
Length
347 amino acids
Function
Catalyzes the formation of Forssman glycolipid via the addition of N-acetylgalactosamine (GalNAc) in alpha-1,3-linkage to GalNAcb-1,3Gala-1,4Galb-1,4GlcCer (Gb4Cer). Forssman glycolipid (also called Forssman antigen; FG) probably serves for adherence of some pathogens such as E.coli uropathogenic strains.
Similarity
Belongs to the glycosyltransferase 6 family.
Mass
40.265 kDa
Sequence
MRCRRLALGLGFSLLSGIALWSLWIYMETWLPFSYVPYYLPCPEIFNMKLQYKGEKPFQPVTRSPHPQPKLLEQRPTELLTLTPWLAPIVSEGTFNPELLQHIYQPLNLTIGLTVFAVGKYTRFVQHFLESAEQFFMQGYQVYYYIFTNDPAGIPRVPLGPGRLLSIIPIQRHSRWEEISTRRMETISRHIAQRAHREVDYLFCVDVDMVFRNPWGPETLGDLVAAIHPGYYAVPRQQFPYERRHISTAFVAENEGDFYYGGAVFGGRVAKVYEFTTGCHMAILADKANGIMAAWQEESHLNRRFISHKPSKVLSPEYLWDDRKPQPPSLKLIRFSTLDKATSWLRS

Gene
GBGT1
Protein
Globoside alpha-1,3-N-acetylgalactosaminyltransferase 1
Organism
Homo sapiens
Length
347 amino acids
Function
Catalyzes the formation of some glycolipid via the addition of N-acetylgalactosamine (GalNAc) in alpha-1,3-linkage to some substrate. Glycolipids probably serve for adherence of some pathogens.
Similarity
Belongs to the glycosyltransferase 6 family.
Mass
40.127 kDa
Sequence
MHRRRLALGLGFCLLAGTSLSVLWVYLENWLPVSYVPYYLPCPEIFNMKLHYKREKPLQPVVWSQYPQPKLLEHRPTQLLTLTPWLAPIVSEGTFNPELLQHIYQPLNLTIGVTVFAVGKYTHFIQSFLESAEEFFMRGYRVHYYIFTDNPAAVPGVPLGPHRLLSSIPIQGHSHWEETSMRRMETISQHIAKRAHREVDYLFCLDVDMVFRNPWGPETLGDLVAAIHPSYYAVPRQQFPYERRRVSTAFVADSEGDFYYGGAVFGGQVARVYEFTRGCHMAILADKANGIMAAWREESHLNRHFISNKPSKVLSPEYLWDDRKPQPPSLKLIRFSTLDKDISCLRS

Gene
Gbgt1
Protein
Globoside alpha-1,3-N-acetylgalactosaminyltransferase 1
Organism
Mus musculus
Length
347 amino acids
Function
Catalyzes the formation of Forssman glycolipid via the addition of N-acetylgalactosamine (GalNAc) in alpha-1,3-linkage to GalNAcb-1,3Gala-1,4Galb-1,4GlcCer (Gb4Cer). Forssman glycolipid (also called Forssman antigen; FG) probably serves for adherence of some pathogens. Conversely, it diminishes Shiga toxins susceptibility.
Similarity
Belongs to the glycosyltransferase 6 family.
Mass
40.502 kDa
Sequence
MTRPRLAQGLAFFLLGGTGLWVLWKFIKDWLLVSYIPYYLPCPEFFNMKLPFRKEKPLQPVTQLQYPQPKLLEHGPTELLTLTPWLAPIVSEGTFDPELLKSMYQPLNLTIGVTVFAVGKYTCFIQRFLESAEEFFMRGYQVHYYLFTHDPTAVPRVPLGPGRLLSIIPIQGYSRWEEISMRRMETINKHIAKRAHKEVDYLFCVDVDMVFRNPWGPETLGDLVAAIHPGYFAVPRRKFPYERRQVSSAFVADNEGDFYYGGALFGGRVARVYEFTRACHMAILADKANSIMAAWQEESHLNRHFIWHKPSKVLSPEYLWDERKPRPRSLKMIRFSSVKKNANWLRT

Gene
GBGT1
Protein
Globoside alpha-1,3-N-acetylgalactosaminyltransferase 1
Organism
Gallus gallus
Length
343 amino acids
Function
Catalyzes the formation of some glycolipid via the addition of N-acetylgalactosamine (GalNAc) in alpha-1,3-linkage to some substrate. Glycolipids probably serve for adherence of some pathogens (By similarity).
Similarity
Belongs to the glycosyltransferase 6 family.
Mass
39.652 kDa
Sequence
MISRKALGSLVCLSAVATLIWIASGNWKVHYLPYYLPCPGIFSKKLQYLGDKPVQLFPQLFYQQPRVLAPKRQDVLTVTPWLAPIVWEGTFSPEILDSAYMPLNLTIGVTAFAVGKYTRFVSRFLKSAEMHFMKGYRVNYYIFTDNPKMIPDVQLQPGRRFDVVHIKKYSSWQEISVRRMEAINLHIAERSHREVDYLFCLDIDMVFHNAWGAETLGDMVAAIHPGYFNVPRSQFPYERRSSSAAYIPDGEGDFYYGGAVFGGLVKKVYEFTKICHMTILADKANGIMAAWQEESHLNRHFLTHKPSKLLSPEYLWDDRKPKPPEIFLIRFSTVDKNYQEVRN