GATA5

Gene

Gata5

Protein

Transcription factor GATA-5

Organism

Mus musculus

Length

404 amino acids

Function

Transcription factor required during cardiovascular development (By similarity). Plays an important role in the transcriptional program(s) that underlies smooth muscle cell diversity (PubMed:9119112). Binds to the functionally important CEF-1 nuclear protein binding site in the cardiac-specific slow/cardiac troponin C transcriptional enhancer (By similarity).

Mass

42.114 kDa

Sequence

MYQSLALAQSPGQGTYADSGAFLHSSGTGSPVFVAPTRMPSMLPYLPSCEPGSQAPALAAHSSWTQAVAADSSAFGSGSPHPPAAHPPGATTFPFAHSPPGSGSGGSAGVRDGGAFQGALLAREQYPTPLGRPMGASYPTTYPAYMSSDVAPSWTSGAFDSSILHGLQARPGGLPGRRTSFVPDFLEEFPGEGRECVNCGALSTPLWRRDGTGHYLCNACGLYHKMNGVNRPLVRPQKRLSSSRRSGLCCSNCHTATTTLWRRNSEGEPVCNACGLYMKLHGVPRPLAMKKESIQTRKRKPKNPAKIKGSSGSTANTTASSPTLLNSESSATTLKAESSLASPVCAGPTITSQASSPADESLASSHLEFKFEPEDFAFTSSSMSPQAGLSGVLRQETWCALALA

Protein

Transcription factor GATA-5: Gata5

Gene

Gata5

Protein

Transcription factor GATA-5

Organism

Mus musculus

Length

404 amino acids

Function

Mass

42.114 kDa

Sequence

Protein

Transcription factor GATA-5: Gata5

Gene

GATA5

Protein

Transcription factor GATA-5

Organism

Bos taurus

Length

403 amino acids

Function

Transcription factor required during cardiovascular development. Plays an important role in the transcriptional program(s) that underlies smooth muscle cell diversity. Binds to the functionally important CEF-1 nuclear protein binding site in the cardiac-specific slow/cardiac troponin C transcriptional enhancer (By similarity).

Mass

41.603 kDa

Sequence

MYQSLALAPSPGQTAYADSGAFLHTPGAGSPVFVPPARVPSMLPYLPACEPGPQAPAITAHPGWAQAAAADSSAFGSGSPHAPAAPPPGTTAFPFAHSSPGPGGGTGTRDNGAFQGAMLAREQYPAALGRPVSSSYPTAYPAYMSAEVAPSWTSGPLDGSVLHSLQGLPAGLPGRRAPFAAELLEEFPGEGRECVNCGALSTPLWRRDGTGHYLCNACGLYHKMNGVNRPLVRPQKRLSSSRRAGLCCTNCHTTTTTLWRRNVDGEPVCNACGLYMKLHGVPRPLAMKKESIQTRKRKPKNIAKTKGSSGSSGHTTASPQASVPDPEVSAATLKPEPSLASPSCPGPSVTSQGSAQVDDPLAPSHLEFKFEPEDFALPSAALGQQAGLGGALRQEAWCALALA

Protein

Transcription factor GATA-5: GATA5

Gene

GATA5

Protein

Transcription factor GATA-5

Organism

Bos taurus

Length

403 amino acids

Function

Mass

41.603 kDa

Sequence

Protein

Transcription factor GATA-5: GATA5

Gene

GATA5

Protein

Transcription factor GATA-5

Organism

Homo sapiens

Length

397 amino acids

Function

Transcription factor required during cardiovascular development (PubMed:23289003). Plays an important role in the transcriptional program(s) that underlies smooth muscle cell diversity (By similarity). Binds to the functionally important CEF-1 nuclear protein binding site in the cardiac-specific slow/cardiac troponin C transcriptional enhancer (PubMed:25543888).

Mass

41.299 kDa

Sequence

MYQSLALAASPRQAAYADSGSFLHAPGAGSPMFVPPARVPSMLSYLSGCEPSPQPPELAARPGWAQTATADSSAFGPGSPHPPAAHPPGATAFPFAHSPSGPGSGGSAGGRDGSAYQGALLPREQFAAPLGRPVGTSYSATYPAYVSPDVAQSWTAGPFDGSVLHGLPGRRPTFVSDFLEEFPGEGRECVNCGALSTPLWRRDGTGHYLCNACGLYHKMNGVNRPLVRPQKRLSSSRRAGLCCTNCHTTNTTLWRRNSEGEPVCNACGLYMKLHGVPRPLAMKKESIQTRKRKPKTIAKARGSSGSTRNASASPSAVASTDSSAATSKAKPSLASPVCPGPSMAPQASGQEDDSLAPGHLEFKFEPEDFAFPSTAPSPQAGLRGALRQEAWCALALA

Protein

Transcription factor GATA-5: GATA5

Gene

GATA5

Protein

Transcription factor GATA-5

Organism

Homo sapiens

Length

397 amino acids

Function

Mass

41.299 kDa

Sequence

Protein

Transcription factor GATA-5: GATA5

Gene

GATA5

Protein

Transcription factor GATA-5

Organism

Gallus gallus

Length

391 amino acids

Function

Probably involved in bone morphogenetic protein (BMP)-mediated cardiac-specific gene expression. Binds to BMP response element (BMPRE) DNA sequences within cardiac activating regions.

Mass

41.859 kDa

Sequence

MYQGLALAPNHGQSAYSHDSGNFLHSSAGSPVYVPTTRVPSVLQTLPYLQSCEPHQSHLGNPPGWAQSSGETTAFNAGSPHPPSGFSYPHSPRAAAPRGVDGAYQGPLLLGGGGREQYGNALVRSVNGSYSSPYPAYVTPELPPSWTAGHFESSVLHSLQTRQAALPGRRSTFEYLEEFPGDGRECVNCGAMSTPLWRKDGTGHYLCNACGLYHKMNGINRPLKPQKRLSSSRRAGLCCTNCHTTNTTLWRRNAEGEPVCNACGLYMKLHGVPRPLAMKKESIQTRKRKPKNITKGKTSTGSTTSATNSPSSITNSDSTVTLKSEPSTTSQYPGQGIVSVSQAQSQSDEALAGGEFKFEPEDYPFSPSSMAPQPGLSVPLRQDSWCALALA

Protein

Transcription factor GATA-5: GATA5

Gene

GATA5

Protein

Transcription factor GATA-5

Organism

Gallus gallus

Length

391 amino acids

Function

Probably involved in bone morphogenetic protein (BMP)-mediated cardiac-specific gene expression. Binds to BMP response element (BMPRE) DNA sequences within cardiac activating regions.

Mass

41.859 kDa

Sequence

Protein

Transcription factor GATA-5: GATA5

Gene

GATA5

Protein

GATA transcription factor 5

Organism

Arabidopsis thaliana

Length

339 amino acids

Function

Transcriptional activator that specifically binds 5'-GATA-3' or 5'-GAT-3' motifs within gene promoters. May be involved in the regulation of some light-responsive genes (By similarity).

Similarity

Belongs to the type IV zinc-finger family. Class A subfamily.

Mass

37.091 kDa

Sequence

MEQAALKSSVRKEMALKTTSPVYEEFLAVTTAQNGFSVDDFSVDDLLDLSNDDVFADEETDLKAQHEMVRVSSEEPNDDGDALRRSSDFSGCDDFGSLPTSELSLPADDLANLEWLSHFVEDSFTEYSGPNLTGTPTEKPAWLTGDRKHPVTAVTEETCFKSPVPAKARSKRNRNGLKVWSLGSSSSSGPSSSGSTSSSSSGPSSPWFSGAELLEPVVTSERPPFPKKHKKRSAESVFSGELQQLQPQRKCSHCGVQKTPQWRAGPMGAKTLCNACGVRYKSGRLLPEYRPACSPTFSSELHSNHHRKVIEMRRKKEPTSDNETGLNQLVQSPQAVPSF

Protein

GATA transcription factor 5: GATA5

Gene

GATA5

Protein

GATA transcription factor 5

Organism

Arabidopsis thaliana

Length

339 amino acids

Function

Transcriptional activator that specifically binds 5'-GATA-3' or 5'-GAT-3' motifs within gene promoters. May be involved in the regulation of some light-responsive genes (By similarity).

Similarity

Belongs to the type IV zinc-finger family. Class A subfamily.

Mass

37.091 kDa

Sequence

Protein

GATA transcription factor 5: GATA5