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GART

Gene
GART
Protein
Trifunctional purine biosynthetic protein adenosine-3
Organism
Chironomus tentans
Length
1371 amino acids
Similarity
In the C-terminal section; belongs to the GART family.
Mass
149.103 kDa
Sequence
MTGKKLLLIGSGGREHALAWKLQQSKNVTEIFAFPGSIGISQLEKVQLVNNNEMNLKDFKGIASWCKINHIDLVIVGPEDPLAEGIADQLKAANIHCFGPSKAGARIESDKSWSKDFMIRHHIPTAQYGSFIDALKAKDFIRNTPNALVVKASGLAAGKGVIVAENIEEACAAVDEILGDHKFGTAGDVVVVEEKLSGQEVSVLGFVDSNSVRILPPAQDHKRLKDNDEGLNTGGMGAYCPCPLISQQELDIVKSQVLQRAVDGLRKENILYNGILYAGIMLTHDGPKTLEFNCRFGDPETQIILPLLDEDLYDLMMASCTNHLCNVPELKFKSNINAVGVVMASKGYPETSTKGCVISGIESVETMDNHIVFHSGTSKNNKDEWITNGGRVLINIALADNLKKAADLATKACDVVKFDGSQYRRDIGKKAFQIHSLTYKESGVNIEAGNSLVGRIKSLSYGTHRSGVVGQIGSFGGLMRLNDIKYINSNGEESNYKDIVLVQGTDGVGTKLKIAESMNVWDTIGIDLVAMCVNDVLCNGAEPIGFLDYIACGHLEVPTVATIVKGIADGCRKANCALIGGETAEMPSMYGKGKYDLAGYCVGITEYDEILPKINDVHVGDVVIGLPSSGIHSNGFSLVNKIFQQTGFKLTDIAEFSDSHKSYGMEFLTPTRLYVSETLPFLRNGYVKALAHITGGGLLENIPRILPNHLSVQIDALTWKLPKVFSWLAAHGNVNANEMLRTFNCGIGMIIIMPRNDIEWETIPEARMIGSITQRDHNGPQVIVKNFKEVLHKEVTHWKKGDAETTSISYKDSGVDITAGNELVDNIKPHAKSTNRKGVIGGLGSFGGLFRINECGTKFEDPMLVLATDGVGTKLKIAQQLGKHDTVGIDLVAMCNNDILCNGAEPLTFLDYFACGKLDVNVATNVVSGIAEGCRQSDSTLLGGETAEMPGMYNPNVYDLAGFSLGVAEHEDILPKKNCLEVGDIIIGFPSNGVHSNGFSLIHKLFELTGYKWTDIAPFSAYGKTFGEEFLEPTKVYVKEISPALKTGYVKALAHITGGGLWDNIPRVLPYNLTAELDAKKINISPVFAWLSLNGNIDKLELLKTFNCGIGMIMIASKEHELEILKSLYGSRASVIGKIIPTKPHGHQVIVRHFATCFERVERLLSIPKKRVGVLISGSGSNLQALIDATKSTNMGMCSEIVFVLSNKAGIFGLERAAKANIPSTVISNKDYATREAFDVALHNELIKHNVEIICLAGFMRILTPCFVNKWKGKLLNIHPSLLPKYKGITAQKDALESGDNESGCTVHFVDENVDTGAIIVQEIVPIFENDTVESLTERIHVAEHIAFPKALRLVASGYVRLNDKCETEWA

Gene
Gart
Protein
Trifunctional purine biosynthetic protein adenosine-3
Organism
Drosophila melanogaster
Length
1353 amino acids
Function
Trifunctional enzyme required for de novo purine biosynthesis.
Similarity
In the C-terminal section; belongs to the GART family.
Mass
144.448 kDa
Sequence
MSHRVLVIGSGGREHAICWKLSQSPKVAQIYALPGSHGIQLVEKCRNLDAKTLDPKDFEAIAKWSKENQIALVVVGPEDPLALGLGDVLQSAGIPCFGPGKQGAQIEADKKWAKDFMLRHGIPTARYESFTDTEKAKAFIRSAPYPALVVKAAGLAAGKGVVVAANAKEACQAVDEILGDLKYGQAGATLVVEELLEGEEVSVLAFTDGKSVRAMLPAQDHKRLGNGDTGPNTGGMGAYCPCPLISQPALELVQKAVLERAVQGLIKERINYQGVLYAGLMLTRDGPRVLEFNCRFGDPETQVILPLLESDLFDVMEACCSGKLDKIPLQWRNGVSAVGVILASAGYPETSTKGCIISGLPAANTPTQLVFHSGLAVNAQKEALTNGGRVLIAIALDGSLKEAAAKATKLAGSISFSGSGAQYRTDIAQKAFKIASASTPGLSYKDSGVDIDAGDALVQRIKPLSRGTQRPGVIGGLGGFGGLFRLKELTYKEPVIAEATQGVGAKIHLALTHEFYENVGYDLFALAANDVLEVGAEPVAFLDYIACGKLQVPLAAQLVKGMADGCRDARCALVGGETAEMPSLYAPGQHDMAGYCVGIVEHSRILPRFDLYQPGDLLIGLPSSGLHCAGFNEILTQLAASKVNLRERSPVDGGDDGLTLAHVLATPTQLYVQQLLPHLQKGDEIKSVAHVTHGLLNDILRLLPDGFETTLDFGAVPVPKIFGWLAGKLKLSAQTILERHNCGIGMVLILPQSSQLWRTSLPGAKVLGVLQRRSKVSGSPVQVRNFVEQLEKVASPFGGLGDRELPEELKKLPSNSDLSAPREECFENAAGRRLTRIPTHYKDPILILGTDGVGTKLKIAQQTNRNTSVGIDLVAMCVNDILCNGAEPISFSSYYACGHWQEQLAKGVHSGVQEGARQANSSFIDSHSAALPLLYEPQVYDLAGFALGIAEHTGILPLLAEIQPGDVLIGLPSSGVHSNGFSLVHAVLKRVGLGLHDKAPFSDKTLGEELLVPTKIYVKALSTLLSRGKHGIKALAHITGGGLSENIPRVLRKDLAVRLDANKFQLPPVFAWLAAAGNISSTELQRTYNCGLGMVLVVAPTEVEDVLKELRYPQRAAVVGEVVARKDPKKSQVVVQNFEASLARTQKMLSQRRKRVAVLISGTGSNLQALIDATRDSAQGIHADVVLVISNKPGVLGLQRATQAGIPSLVISHKDFASREVYDAELTRNLKAARVDLICLAGFMRVLSAPFVREWRGRLVNIHPSLLPKYPGLHVQKQALEAGEKESGCTVHFVDEGVDTGAIIVQAAVPILPDDDEDSLTQRIHKAEHWAFPRALAMLVNGTALISPEVSSQ

Gene
GART
Protein
Trifunctional purine biosynthetic protein adenosine-3
Organism
Bos taurus
Length
1010 amino acids
Similarity
In the C-terminal section; belongs to the GART family.
Mass
107.907 kDa
Sequence
MAARVLVIGNGGREHTLAWKLAQSTHVKQVLVTPGNAGTACSEKISNTDISISDHTALAQFCKDEKIEFVVVGPEAPLAAGIVGNLNSVGVRCFGPTAQAAQLESSKRFAKEFMDRHGISTARWRAFTKPKEACDFIMSADFPALVVKASGLAAGKGVIVAKSKEEACEAVREIMQGKAFGEAGETVVIEELLEGEEVSCLCFTDGRTVAPMPPAQDHKRLLEGDEGPNTGGMGAYCPAPQVSKDLLLKIKNNILQRTVDGMQEEGMPYTGVLYAGIMLTKNGPKVLEFNCRFGDPECQVILPLLKSDLYEVIQSILDGLLCTSLPVWLDNCAAVTVVMASKGYPGDYTKGVEITGFPEAQALGLEVFQAGTALKDGKVVTNGGRVLTVTAIRENLISALEEARKGLAAIKFEGAVYRKDIGFRAIAFLQQPRGLTYKESGVDIAAGNMLVQKIKPLAKATSRPGCDVDLGGFAGLFDLKAAGFTDPLLACGTDGVGTKLKIAQQCSKHDTIGQDLVAMCVNDILAQGAEPLFFLDYFSCGKLDLRTTEAVITGIAKACKKAGCALLGGETAEMPDMYPPGEYDLAGFAVGAMERDQKLPQLERITEGDAVIGIASSGLHSNGFSLVRKIVAKSSLEYSSPAPGGCGDQTLGDLLLTPTKIYSRSLLPVLRSGRVKAVAHITGGGLLENIPRVLPQKLGVNLDAQTWRVPRIFSWLQQEGHLSEEEMARTFNCGIGAALVVSEDLVKQTLQDIEQHQEEACVIGRVVACPKGSPRVKVEHLIETMQINGSVLENGTLRNHFSVQPKKARVAVLISGTGSNLQALIDSTREPSSLAHIVIVISNKAAVAGLDKAEKAGIPTRVINHKLYKNRAAFDTAIDEVLEEFSTDIVCLAGFMRILSGPFVRKWNGKMLNIHPSLLPSFKGSNAHEQVLDAGVTVTGCTVHFVAEDVDAGQIILQEAVPVKRGDTVETLSERVKLAEHKIFPSALQLVASGAVRLGENGRICWVTED

Gene
Gart
Protein
Trifunctional purine biosynthetic protein adenosine-3
Organism
Mus musculus
Length
1010 amino acids
Similarity
In the C-terminal section; belongs to the GART family.
Mass
107.503 kDa
Sequence
MAARVLVIGSGGREHTLAWKLAQSPQVKQVLVAPGNAGTACAGKISNAAVSVNDHSALAQFCKDEKIELVVVGPEAPLAAGIVGDLTSAGVRCFGPTAQAAQLESSKKFAKEFMDRHEIPTAQWRAFTNPEDACSFITSANFPALVVKASGLAAGKGVIVAKSQAEACRAVQEIMQEKSFGAAGETVVVEEFLEGEEVSCLCFTDGKTVAEMPPAQDHKRLLDGDEGPNTGGMGAYCPAPQVSKDLLVKIKNTILQRAVDGMQQEGAPYTGILYAGIMLTKDGPKVLEFNCRFGDPECQVILPLLKSDLYEVMQSTLDGLLSASLPVWLENHSAVTVVMASKGYPGAYTKGVEITGFPEAQALGLQVFHAGTALKDGKVVTSGGRVLTVTAVQENLMSALAEARKGLAALKFEGAIYRKDIGFRAVAFLQRPRGLTYKDSGVDIAAGNMLVKKIQPLAKATSRPGCSVDLGGFAGLFDLKAAGFKDPLLASGTDGVGTKLKIAQLCNKHDSIGQDLVAMCVNDILAQGAEPLFFLDYFSCGKLDLSTTEAVIAGIAAACQQAGCALLGGETAEMPNMYPPGEYDLAGFAVGAMERHQKLPQLERITEGDAVIGVASSGLHSNGFSLVRKIVERSSLQYSSPAPGGCGDQTLGDLLLTPTRIYSHSLLPIIRSGRVKAFAHITGGGLLENIPRVLPQKFGVDLDASTWRVPKVFSWLQQEGELSEEEMARTFNCGIGAALVVSKDQAEQVLHDVRRRQEEAWVIGSVVACPEDSPRVRVKNLIETIQTNGSLVANGFLKSNFPVQQKKARVAVLISGTGSNLQALIDSTRDPKSSSHIVLVISNKAAVAGLDRAERAGIPTRVINHKLYKNRVEFDNAVDHVLEEFSVDIVCLAGFMRILSGPFVRKWDGKMLNIHPSLLPSFKGSNAHEQVLEAGVTITGCTVHFVAEDVDAGQIILQEAVPVRRGDTVATLSERVKVAEHKIFPAALQLVASGAVQLREDGKIHWAKEQ

Gene
GART
Protein
Trifunctional purine biosynthetic protein adenosine-3
Organism
Homo sapiens
Length
1010 amino acids
Similarity
In the C-terminal section; belongs to the GART family.
Mass
107.767 kDa
Sequence
MAARVLIIGSGGREHTLAWKLAQSHHVKQVLVAPGNAGTACSEKISNTAISISDHTALAQFCKEKKIEFVVVGPEAPLAAGIVGNLRSAGVQCFGPTAEAAQLESSKRFAKEFMDRHGIPTAQWKAFTKPEEACSFILSADFPALVVKASGLAAGKGVIVAKSKEEACKAVQEIMQEKAFGAAGETIVIEELLDGEEVSCLCFTDGKTVAPMPPAQDHKRLLEGDGGPNTGGMGAYCPAPQVSNDLLLKIKDTVLQRTVDGMQQEGTPYTGILYAGIMLTKNGPKVLEFNCRFGDPECQVILPLLKSDLYEVIQSTLDGLLCTSLPVWLENHTALTVVMASKGYPGDYTKGVEITGFPEAQALGLEVFHAGTALKNGKVVTHGGRVLAVTAIRENLISALEEAKKGLAAIKFEGAIYRKDVGFRAIAFLQQPRSLTYKESGVDIAAGNMLVKKIQPLAKATSRSGCKVDLGGFAGLFDLKAAGFKDPLLASGTDGVGTKLKIAQLCNKHDTIGQDLVAMCVNDILAQGAEPLFFLDYFSCGKLDLSVTEAVVAGIAKACGKAGCALLGGETAEMPDMYPPGEYDLAGFAVGAMERDQKLPHLERITEGDVVVGIASSGLHSNGFSLVRKIVAKSSLQYSSPAPDGCGDQTLGDLLLTPTRIYSHSLLPVLRSGHVKAFAHITGGGLLENIPRVLPEKLGVDLDAQTWRIPRVFSWLQQEGHLSEEEMARTFNCGVGAVLVVSKEQTEQILRDIQQHKEEAWVIGSVVARAEGSPRVKVKNLIESMQINGSVLKNGSLTNHFSFEKKKARVAVLISGTGSNLQALIDSTREPNSSAQIDIVISNKAAVAGLDKAERAGIPTRVINHKLYKNRVEFDSAIDLVLEEFSIDIVCLAGFMRILSGPFVQKWNGKMLNIHPSLLPSFKGSNAHEQALETGVTVTGCTVHFVAEDVDAGQIILQEAVPVKRGDTVATLSERVKLAEHKIFPAALQLVASGTVQLGENGKICWVKEE

Gene
GART
Protein
Trifunctional purine biosynthetic protein adenosine-3
Organism
Gallus gallus
Length
1003 amino acids
Similarity
In the C-terminal section; belongs to the GART family.
Mass
106.544 kDa
Sequence
MADRVLVIGSGGREHALAWKLAQSPHVKQVFVAPGNAGTANSGKISNSAVSVSNHAALAQFCRDQEIRLVVVGPEVPLAAGIVDDLTAAGVRCFGPTARAAQLESSKSFTKSFLDRHGIPTARWKSFTDPKAACSFINSANFPALVVKASGLAAGKGVIVASNKEEACKAVNDIMQDKTFGTAGETVVVEELLEGEEVSCLCFTDGVTIAPMPPAQDHKRLKDGDEGPNTGGMGAYSPAPQISKDLLLKIRETVLQKTLDGMRKEGIPYLGVLYAGLMLTKDGPKVLEFNCRFGDPECQVILPLLKSDLYEVMQAVINKKLSSSMPIWYEDSAAVTVVMASEGYPGTYPKGLEITGLSKAKELGLEVFHAGTALKDGKVVTNGGRVLTVTAIKEDLMTALQEANKGVAAINFKGSIYRKDIGYRAIAFLSQSRGLTYKNSGVDIAAGNILVQKIKPLAAATSRSGCNAELGGFAGLFDLKAAGYKDPILVSGTDGVGTKLKIAQVCKKHDTIGQDLVAMCVNDILAQGAEPLFFLDYFACGKLDVEVAQGVIAGIAEACQKAGCALLGGETAEMPGMYPPGEYDLAGFAVGAVERGQMLPQLERIADGDVVIGVASSGVHSNGYSLVRRIVEKSSLDFSSQVGVSGDQTLGDLLLTPTKIYSKTLLPVLRSGHVKAYAHITGGGLLENIPRVLPDSFGVVLDALSWKIPEIFCWLHKEGNLSEEEMARTFNCGIGAVLVVQKELAQQVLKDVQKHEAAWLIGKVVPLQKGSAHVKVHNLLQALQANRSLSVHSHIQGKIQTNKVKVAVLISGTGTNLEALINSTKKPTSFAEIVLVVSNKAGVEGLRKAERAGIPTRVIDHKQYGSRTEFDSAVDRVLEEFSVELICLAGFMRILSGPFVKKWEGKILNIHPSLLPSFKGANAHKLVLEAGVRVTGCTVHFVAEEVDAGAIIFQEAVPVKIGDTVETLSERVKEAEHRAFPAALQLVASGAVQVGEAGKICWK