G5R

Gene

G5R

Protein

Putative nuclease G5

Organism

Vaccinia virus (strain Copenhagen)

Length

434 amino acids

Function

Putative nuclease that seems to be required for double-strand break repair, homologous recombination, and production of full-length viral genomic DNA.

Similarity

Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.

Mass

49.873 kDa

Sequence

MGIKNLKSLLLENKSLTILDDNLYKVYNGIFVDTMSIYIAVANCVRNLEELTTVFIKYVNGWVKKGGHVTLFIDRGSIKIKQDVRDKRRKYSKLTKDRKMLELEKCTSEIQNVTGFMEEEIKAEMQLKIDKLTFQIYLSDSDNIKISLNEILTHFNNNENVTLFYCDERDAEFVMCLEAKTHFSTTGEWPLIISTDQDTMLFASTDNHPKMIKNLTQLFKFVPSAEDNYLAKLTALVNGCDFFPGLYGASITPNNLNKIQLFSDFTIDNIVTSLAIKNYYRKTNSTVDVRNIVTFINDYANLDDVYSYVPPCQCTVQEFIFSALDEKWNNFKSSYLETVPLPCQLMYALEPRKEIDVSEVKTLSSYIDFENTKSDIDVIKSISSIFGYSNENCNTIVFGIYKDNLLLSINNSFYFNDSLLITNTKSDNIINIGY

Protein

Putative nuclease G5: G5R

Gene

G5R

Protein

Putative nuclease G5

Organism

Variola virus (isolate Human/India/Ind3/1967)

Length

434 amino acids

Function

Putative nuclease that seems to be required for double-strand break repair, homologous recombination, and production of full-length viral genomic DNA.

Similarity

Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.

Mass

49.884 kDa

Sequence

MGIKNLKSLLLENKSLTILDDNLYKVYNGIFVDTMSIYIAVANCVRNLEELTTVFIKYVNGWVKKGGHVTLFIDRGSIKIKQNVRDKRRKYSKSTKDRKMLELEKCTSKIQNVTGFMEEEIKAEIQLKIDKLTFQIYLSDSDNIKISLNEILTHFNNNENVTLFYCDERDAEFVMCLEAKTYFFTTGEWPLIISTDQDTMLFASVDNHPKMIKNLTQLFKFVPSAEDNYLAKLTALVNGCDFFPGLYGASITPTNLNKIQLFSDFTINNIVTSLAIKNYYRKTNSTVDVRNIVTFINDYANLDDVYSYIPPCQCTVQEFIFSALDEKWNDFKSSYLETVPLPCQLMYALEPRKEIDVSEVKTLSSYIDFENTKSDIDVIKSISSIFGYSNENCNTIVFGIYKDNLLLSINSSFYFNNSLLITNTKSDNIINIGY

Protein

Putative nuclease G5: G5R