FOSL2

Gene

FOSL2

Protein

Fos-related antigen 2

Organism

Homo sapiens

Length

326 amino acids

Function

Controls osteoclast survival and size. As a dimer with JUN, activates LIF transcription. Activates CEBPB transcription in PGE2-activated osteoblasts.

Similarity

Belongs to the bZIP family. Fos subfamily.

Mass

35.193 kDa

Sequence

MYQDYPGNFDTSSRGSSGSPAHAESYSSGGGGQQKFRVDMPGSGSAFIPTINAITTSQDLQWMVQPTVITSMSNPYPRSHPYSPLPGLASVPGHMALPRPGVIKTIGTTVGRRRRDEQLSPEEEEKRRIRRERNKLAAAKCRNRRRELTEKLQAETEELEEEKSGLQKEIAELQKEKEKLEFMLVAHGPVCKISPEERRSPPAPGLQPMRSGGGSVGAVVVKQEPLEEDSPSSSSAGLDKAQRSVIKPISIAGGFYGEEPLHTPIVVTSTPAVTPGTSNLVFTYPSVLEQESPASPSESCSKAHRRSSSSGDQSSDSLNSPTLLAL

Protein

Fos-related antigen 2: FOSL2

Gene

Fosl2

Protein

Fos-related antigen 2

Organism

Mus musculus

Length

326 amino acids

Function

Controls osteoclast survival and size. As a dimer with JUN, activates LIF transcription. Activates CEBPB transcription in PGE2-activated osteoblasts (By similarity).

Similarity

Belongs to the bZIP family. Fos subfamily.

Mass

35.298 kDa

Sequence

MYQDYPGNFDTSSRGSSGSPAHAESYSSGGGGQQKFRVDMPGSGSAFIPTINAITTSQDLQWMVQPTVITSMSNPYPRSHPYSPLPGLASVPGHMALPRPGVIKTIGTTVGRRRRDEQLSPEEEEKRRIRRERNKLAAAKCRNRRRELTEKLQAETEELEEEKSGLQKEIAELQKEKEKLEFMLVAHGPVCKISPEERRSPPTSGLQSLRGTGSAVGPVVVKQEPPEEDSPSSSAGMDKTQRSVIKPISIAGGGFYGEEPLHTPIVVTSTPAITPGTSNLVFTYPNVLEQESPSSPSESCSKAHRRSSSSGDQSSDSLNSPTLLAL

Protein

Fos-related antigen 2: Fosl2

Gene

Fosl2

Protein

Fos-related antigen 2

Organism

Rattus norvegicus

Length

326 amino acids

Function

Controls osteoclast survival and size (By similarity). As a dimer with JUN, activates LIF transcription (By similarity). Activates CEBPB transcription in PGE2-activated osteoblasts.

Similarity

Belongs to the bZIP family. Fos subfamily.

Mass

35.255 kDa

Sequence

MYQDYPGNFDTSSRGSSGSPAHAESYSSGGGGQQKFRVDMPGSGSAFIPTINAITTSQDLQWMVQPTVITSMSNPYPRSHPYSPLPGLASVPGHMALPRPGVIKTIGTTVGRRRRDEQLSPEEEEKRRIRRERNKLAAAKCRNRRRELTEKLQAETEELEEEKSGLQKEIAELQKEKEKLEFMLVAHGPVCKISPEERRSPPTSGLQSLRGTGSAVGPVVVKQEPPEEDSPSSSAGMDKTQRSVIKPISIAGGGFYGEEPLHTPIVVTSTPAITPGTSNLVFTYPSVLEQESPASPSESCSKAHRRSSSSGDQSSDSLNSPTLLAL

Protein

Fos-related antigen 2: Fosl2

Gene

FOSL2

Protein

Fos-related antigen 2

Organism

Gallus gallus

Length

323 amino acids

Similarity

Belongs to the bZIP family. Fos subfamily.

Mass

35.242 kDa

Sequence

MYQDYPGSFDTSSRGSSGSPGHPEPYSAGAAQQKFRVDMPGSGSAFIPTINAITTSQDLQWMVQPTVITSMSSPYSRSHPYSHPLPPLSSVAGHTALQRPGVIKTIGTTVGRRRRDEQLSPEEEEKRRIRRERNKLAAAKCRNRRRELTEKLQAETEVLEEEKSVLQKEIAELQKEKEKLEFMLVAHSPVCKISPEERRSPPTSSLQSVRTGASGAVVVKQEPVEEEIPSSSLVLDKAQRSVIKPISIAGGYYGEEALNTPIVVTSTPAITPGSSNLVFTYPNVLDQESPLSPSESCSKAHRRSSSSGDQSSDSLNSPTLLAL

Protein

Fos-related antigen 2: FOSL2