FLS2

LRR receptor-like serine/threonine-protein kinase FLS2

1183 amino acids

Constitutes the pattern-recognition receptor (PPR) that determines the specific perception of flagellin (flg22), a potent elicitor of the defense response to pathogen-associated molecular patterns (PAMPs). Recognizes flg22 from Pseudomonas aeruginosa and Acidovorax avenae. flg22 is a peptide derived from the bacterial flagellin N-terminus sequence (PubMed:18986259, PubMed:25617720). Does not recognize flg22 from Xanthomonas oryzae pv. oryzae (Xoo) or Xanthomonas oryzae pv. oryzicola (Xoc) (PubMed:25617720).

Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.

124.752 kDa

MERNKFASKMSQHYTKTICIAVVLVAVLFSLSSAAAAGSGAAVSVQLEALLEFKNGVADDPLGVLAGWRVGKSGDGAVRGGALPRHCNWTGVACDGAGQVTSIQLPESKLRGALSPFLGNISTLQVIDLTSNAFAGGIPPQLGRLGELEQLVVSSNYFAGGIPSSLCNCSAMWALALNVNNLTGAIPSCIGDLSNLEIFEAYLNNLDGELPPSMAKLKGIMVVDLSCNQLSGSIPPEIGDLSNLQILQLYENRFSGHIPRELGRCKNLTLLNIFSNGFTGEIPGELGELTNLEVMRLYKNALTSEIPRSLRRCVSLLNLDLSMNQLAGPIPPELGELPSLQRLSLHANRLAGTVPASLTNLVNLTILELSENHLSGPLPASIGSLRNLRRLIVQNNSLSGQIPASISNCTQLANASMSFNLFSGPLPAGLGRLQSLMFLSLGQNSLAGDIPDDLFDCGQLQKLDLSENSFTGGLSRLVGQLGNLTVLQLQGNALSGEIPEEIGNMTKLISLKLGRNRFAGHVPASISNMSSLQLLDLGHNRLDGVFPAEVFELRQLTILGAGSNRFAGPIPDAVANLRSLSFLDLSSNMLNGTVPAALGRLDQLLTLDLSHNRLAGAIPGAVIASMSNVQMYLNLSNNAFTGAIPAEIGGLVMVQTIDLSNNQLSGGVPATLAGCKNLYSLDLSGNSLTGELPANLFPQLDLLTTLNISGNDLDGEIPADIAALKHIQTLDVSRNAFAGAIPPALANLTALRSLNLSSNTFEGPVPDGGVFRNLTMSSLQGNAGLCGGKLLAPCHGHAAGKKRVFSRTGLVILVVLIALSTLLLLMVATILLVSYRRYRRKRRAADIAGDSPEAAVVVPELRRFSYGQLAAATNSFDQGNVIGSSNLSTVYKGVLAGDADGGMVVAVKRLNLEQFPSKSDKCFLTELATLSRLRHKNLARVVGYAWEAGKIKALVLDYMVNGDLDGAIHGGAAAPPPAPSRWTVRERLRVCVSVAHGLVYLHSGYDFPVVHCDVKPSNVLLDGDWEARVSDFGTARMLGVHLPAAANAAAQSTATSSAFRGTVGYMAPEFAYMRTVSTKVDVFSFGVLAMELFTGRRPTGTIEEDGVPLTLQQLVDNAVSRGLDGVHAVLDPRMKVATEADLSTAADVLAVALSCAAFEPADRPDMGAVLSSLLKMSKLVGED

FLS2

LRR receptor-like serine/threonine-protein kinase FLS2

1173 amino acids

Constitutes the pattern-recognition receptor (PPR) that determines the specific perception of flagellin (flg22), a potent elicitor of the defense response to pathogen-associated molecular patterns (PAMPs). Flagellin-binding to the receptor is the first step to initiate the innate immune MAP kinase signaling cascade (MEKK1, MKK4/MKK5 and MPK3/MPK6), resulting in enhanced resistance against pathogens. Binding to the effector AvrPto1 or to the phosphatase hopD2 from Pseudomonas syringae blocks the downstream plant immune response.

Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.

128.824 kDa

MKLLSKTFLILTLTFFFFGIALAKQSFEPEIEALKSFKNGISNDPLGVLSDWTIIGSLRHCNWTGITCDSTGHVVSVSLLEKQLEGVLSPAIANLTYLQVLDLTSNSFTGKIPAEIGKLTELNQLILYLNYFSGSIPSGIWELKNIFYLDLRNNLLSGDVPEEICKTSSLVLIGFDYNNLTGKIPECLGDLVHLQMFVAAGNHLTGSIPVSIGTLANLTDLDLSGNQLTGKIPRDFGNLLNLQSLVLTENLLEGDIPAEIGNCSSLVQLELYDNQLTGKIPAELGNLVQLQALRIYKNKLTSSIPSSLFRLTQLTHLGLSENHLVGPISEEIGFLESLEVLTLHSNNFTGEFPQSITNLRNLTVLTVGFNNISGELPADLGLLTNLRNLSAHDNLLTGPIPSSISNCTGLKLLDLSHNQMTGEIPRGFGRMNLTFISIGRNHFTGEIPDDIFNCSNLETLSVADNNLTGTLKPLIGKLQKLRILQVSYNSLTGPIPREIGNLKDLNILYLHSNGFTGRIPREMSNLTLLQGLRMYSNDLEGPIPEEMFDMKLLSVLDLSNNKFSGQIPALFSKLESLTYLSLQGNKFNGSIPASLKSLSLLNTFDISDNLLTGTIPGELLASLKNMQLYLNFSNNLLTGTIPKELGKLEMVQEIDLSNNLFSGSIPRSLQACKNVFTLDFSQNNLSGHIPDEVFQGMDMIISLNLSRNSFSGEIPQSFGNMTHLVSLDLSSNNLTGEIPESLANLSTLKHLKLASNNLKGHVPESGVFKNINASDLMGNTDLCGSKKPLKPCTIKQKSSHFSKRTRVILIILGSAAALLLVLLLVLILTCCKKKEKKIENSSESSLPDLDSALKLKRFEPKELEQATDSFNSANIIGSSSLSTVYKGQLEDGTVIAVKVLNLKEFSAESDKWFYTEAKTLSQLKHRNLVKILGFAWESGKTKALVLPFMENGNLEDTIHGSAAPIGSLLEKIDLCVHIASGIDYLHSGYGFPIVHCDLKPANILLDSDRVAHVSDFGTARILGFREDGSTTASTSAFEGTIGYLAPEFAYMRKVTTKADVFSFGIIMMELMTKQRPTSLNDEDSQDMTLRQLVEKSIGNGRKGMVRVLDMELGDSIVSLKQEEAIEDFLKLCLFCTSSRPEDRPDMNEILTHLMKLRGKANSFREDRNEDREV

FLS2

Putative inactive flavonol synthase 2

250 amino acids

Belongs to the iron/ascorbate-dependent oxidoreductase family.

28.482 kDa

MEVERDQHISPPSLMAKTIPIIDLSNLDEELVAHAVVKGSEEWGIFHVVNHGIPMDLIQRLKDVGTQFFELPETEKKAVAKQDGSKDFEGYTTNLKYVKGEVWTENLFHRIWPPTCINFDYWPKNPPQYREVIEEYTKETKKLSERILGYLSEGLGLPSEALIQGLGGESTEYVMRINNYPPDPKPDLTLGVPEHTDIIGITIIITNEVPGLQIFKDDHWLDVHYIPSSITVNIGDQIMAEQWKVQECVA