Protein
Peptidyl-prolyl cis-trans isomerase
Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843)
Function
PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Has an important role in sexual development and serves as the target for rapamycin action.
Similarity
Belongs to the FKBP-type PPIase family. FKBP1 subfamily.
Sequence
MGVEKQVISSGNGQDFPKPGDRITMHYTGTLTNGKKFDSSVDRGSPFVCTIGVGQLIRGWDEGVPKMSLGEKAKLTITPDYGYGPRGFPGLIPPNSTLLFDVELLAINDKKA