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FIE2

Gene
FIE2
Protein
Polycomb group protein FIE2
Organism
Zea mays
Length
379 amino acids
Function
Polycomb group (PcG) protein. PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development. PcG proteins are not required to initiate repression, but to maintain it during later stages of development. They probably act via the methylation of histones, rendering chromatin heritably changed in its expressibility (By similarity).
Similarity
Belongs to the WD repeat ESC family.
Mass
42.502 kDa
Sequence
MAKLGPGQGLGCEAAEGSLVPSRKREYKPCGKHTEGKRPLYAIGFNFMDARYYDVFATVGGNRVTTYRCLENGSFALLQAYVDEDKDESFYTLSWARDHVDGSPLLVAAGSNGIIRVINCATEKLAKSFVGHGDSINEIRTQPLKPSLIISASKDESVRLWNVHTGICILIFAGAGGHRNEVLSVDFHPSDIERFASCGMDNTVKIWSMKEFWLYVDKSYSWTDLPSKFPTKYVQFPVLIAAVHSNYVDCTRWLGDFILSKSVDNEIVLWEPKTKEQSPGEGSIDILQKYPVPECDIWFIKFSCDFHFNQLAIGNREGKIYVWEVQSSPPVLIARLYNQQCKSPIRQTAVSFDGSTILGAGEDGTIWRWDEVDHPSSRN

Gene
FIE2
Protein
Polycomb group protein FIE1
Organism
Oryza sativa subsp. japonica
Length
376 amino acids
Function
Polycomb group (PcG) protein. PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development. PcG proteins are not required to initiate repression, but to maintain it during later stages of development. They act via the methylation of histones, rendering chromatin heritably changed in its expressibility (PubMed:23505380, PubMed:24020752). Involved in the regulation of seed endosperm development, grain filling and seed dormancy. FIE2-containing PcG complex in seed endosperm regulates the expression of various transcription factors by trimethylation on histone H3 'Lys-27' (H3K27me3) of target genes. Involved in the overall expression regulation of a large number of nutrient metabolism genes (PubMed:23505380). Involved in the regulation of seed endosperm development. Involved in the regulation of vegetative development, particulary in stem cell maintenance in the root system, where it maintains the suppression of key differentiation regulators (PubMed:24020752).
Similarity
Belongs to the WD repeat ESC family.
Mass
42.036 kDa
Sequence
MAKLGPGQGLGCEAAVGLLAPSRKREYKACNKLTEGKRPLYAIGFNFLDFHYYEVFATVGGNRVTTYSCLKDGNFAILQAYIDEDKDESFYTLSWACDLDGTPLLVAAGSNGIIRVINCATEKLLKTFVGHGDSINEIRTQALKPSLIISASKDESVRLWNVHTGICILIFAGAGGHRNEVLSVDFHPSDIYRIASCGMDNTVKIWSMKEFWPYVEQSFTWTDLPSKFPTKYVQFPVLVAVVHSNYVDCTRWLGDFILSKSVDNEIVLWEPKTKEQSPGEGSIDILQKYPVPECDIWFIKFSCDFHFNQLAIGNREGKVFVWEVQSSPPVLTARLTNPQCKSAIRQTAVSFDGSTILACSEDGSIWRWDEVDHPKA