Protein
Farnesyl diphosphate synthase 1
Organism
Artemisia spiciformis
Function
Catalyzes the sequential condensation of isopentenyl pyrophosphate (IPP) with the allylic pyrophosphates, dimethylallyl pyrophosphate (DMAPP), and then with the resultant geranylpyrophosphate (GPP) to the ultimate product farnesyl pyrophosphate (FPP). Has a 4.5 time greater affinity for GPP versus DMAPP.
Similarity
Belongs to the FPP/GGPP synthase family.
Sequence
MSSSKSIDLKSKFLKVYDTLKSDLINDPAFEFDDDSRQWIQKMLDYNVPGGKLNRGLSVVDSYQLLKGGELSDDEIFLSSALGWCIEWLQAYFLVLDDIMDESHTRRGQPCWFRLPKVGMIAANDGILLRNHVPRILKKHFRGKPYYVDLVDLFNEVEFQTASGQMIDLITTLVGEKDLSKYSLSIHRRIVQYKTAYYSFYLPVACALLMFGEDLDKHVEVKNVLVEMGTYFQVQDDYLDCFGAPEVIGKIGTDIEDFKCSWLVVKALELANEEQKKTLHENYGKKDPASVAKVKEVYHTLNLQAVFEDYEATSYKKLITSIENHPSKAVQAVLKSFLGKIYKRQK