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FCR3

Gene
FCR3
Protein
Fluconazole resistance protein 3
Organism
Candida albicans
Length
399 amino acids
Function
Transcription factor that confers fluconazole resistance in S.cerevisiae by activation of the PDR5 gene. Can also activate the transcription of S.cerevisiae genes involved in 4-nitroquinoline-N-oxide resistance.
Similarity
Belongs to the bZIP family.
Mass
44.483 kDa
Sequence
MNFKTENSTTPNGDWSQSKAFTNSGSSFPVLNGTCELDQENLALSNSGQPESIFTQDSGLHGIDVAAPSDITDLNNQSGYQYNNNLAHDLYFTGSMEMPTTQHPYITNTNNHLSYSNSSEEFSPIGNNMSPDSTGGANSNNFTSGNKRKASNESFSPLSGHHYGTESGNNNNNNGTSRSSQSSSHKSRKKLLDEKDAALIARDDSELTEEELQMKRKAQNRAAQRAFRERKESKLKELEAKLLASEEERQKLLDELEQIKKQNISIATENEILKHNGMGNINNDVQIGNLSSYGRLQVDKFNFPKTQKDFIEHVLQGTNHQLKDENKDKVYNDNQGHKLLALGAVWDYLQIKAEEADLDFNSIDFNDVMEKLKGNEKCHGYGPAYPLELVNEAIESSLN