fbxo45

F-box/SPRY domain-containing protein 1

291 amino acids

Belongs to the FBXO45/Fsn family.

31.298 kDa

MSGAVATGGAQSAGLGAAAAGCCSSASGAGSAALLSGGSGIAGRLPSRVLEHIFSYLELMDLLNCSLVCWHWNNCLSDENSEVWRSLCARSLSDEAMRSDILCNLASYKGKLKSFQHALSSHDCSRNVYIKKNGFTLHRNPIAQSTDGARGKIGFSEGRHAWEIWWEGPLGTVAVIGIATKRAPMQCQGYVALLGSDDQSWGWNLVDNNLLHNGEVNGNFPQCNNAPKYQIGERIRVILDMDDKTLAFERGFEFLGVAFRGLPKTCLFPAVSAVYGNTEVTMVYLGRPLDG

FBXO45

F-box/SPRY domain-containing protein 1

286 amino acids

Component of E3 ubiquitin ligase complexes. Required for normal neuromuscular synaptogenesis, axon pathfinding and neuronal migration (By similarity). Plays a role in the regulation of neurotransmission at mature neurons (By similarity). May control synaptic activity by controlling UNC13A via ubiquitin dependent pathway (By similarity). Specifically recognizes TP73, promoting its ubiquitination and degradation.

Belongs to the FBXO45/Fsn family.

30.633 kDa

MAAPAPGAGAASGGAGCSGGGAGAGAGSGSGAAGAGGRLPSRVLELVFSYLELSELRSCALVCKHWYRCLHGDENSEVWRSLCARSLAEEALRTDILCNLPSYKAKIRAFQHAFSTNDCSRNVYIKKNGFTLHRNPIAQSTDGARTKIGFSEGRHAWEVWWEGPLGTVAVIGIATKRAPMQCQGYVALLGSDDQSWGWNLVDNNLLHNGEVNGSFPQCNNAPKYQIGERIRVILDMEDKTLAFERGYEFLGVAFRGLPKVCLYPAVSAVYGNTEVTLVYLGKPLDG

Fbxo45

F-box/SPRY domain-containing protein 1

286 amino acids

Component of E3 ubiquitin ligase complexes. Required for normal neuromuscular synaptogenesis, axon pathfinding and neuronal migration. Plays a role in the regulation of neurotransmission at mature neurons (By similarity). May control synaptic activity by controlling UNC13A via ubiquitin dependent pathway. Specifically recognizes TP73, promoting its ubiquitination and degradation (By similarity).

Belongs to the FBXO45/Fsn family.

30.605 kDa

MAAPGPGAGAASGGASGGGAGAGGGASAGSGSSGVGGRLPSRVLELVFSYLELSELRSCALVCKHWYRCLHGDENSEVWRSLCARSLAEEALRTDILCNLPSYKAKVRAFQHAFSTNDCSRNVYIKKNGFTLHRNPIAQSTDGARTKIGFSEGRHAWEVWWEGPLGTVAVIGIATKRAPMQCQGYVALLGSDDQSWGWNLVDNNLLHNGEVNGSFPQCNNAPKYQIGERIRVILDMEDKTLAFERGYEFLGVAFRGLPKACLYPAVSAVYGNTEVTLVYLGKPLDG

fbxo45

F-box/SPRY domain-containing protein 1

282 amino acids

Belongs to the FBXO45/Fsn family.

30.984 kDa

MAAAAINAAAPPPPVAPTAPPPPPPPPLSQASGRLPSRVLELVFSYLDLPDLRSCGLVCKHWYRCLHGDENSEVWRSLCGRIVSEEALRTDILCNLPTYKAKMRAFQHGFSSSDCSRNVYIKKNGFTLHRNPIAQSTDGARTKIGFSEGRHAWEVWWEGPLGTVAVIGIATKRAPMQCQGYVALLGSDDQSWGWNLVDNNLLHNGEVNGSFPQCNNAPKYQIGERIRVILDMEDKTLAFERGYEFLGVAFRGLPKTCLYPAVSAVYGNTEVTLVYLGKPLDG

fbxo45

F-box/SPRY domain-containing protein 1

280 amino acids

Belongs to the FBXO45/Fsn family.

30.824 kDa

MAAAINAAVPSPPVAPSAPPPPPPPLGQASDRFPSLVLELVFSYLDLPDLRSCGLVCKRWYRCLHGDKNSDVWRSLCCRIVSEEALRTDILCNLRTYKAKVRAFQHGLSSSDCSRNVFIKKNGFTLHRNPIAQSTDGARTKIGFSEGRHAWEVWWEGPLGTVAVIGIATKQAPMQCQGYVALLGSDDQSWGWNLVDNNLLHNGEVNGSFPQCNNAPKYQIGERIRVILDMEDKTLAFERGYEYLGVAFRGLPKACLYPAVSAVYGNTEVTLVYLGKPLDG

Fbxo45

F-box/SPRY domain-containing protein 1

230 amino acids

Component of E3 ubiquitin ligase complexes (By similarity). Required for normal neuromuscular synaptogenesis, axon pathfinding and neuronal migration (By similarity). Plays a role in the regulation of neurotransmission at mature neurons. May controls synaptic activity by controlling UNC13A via ubiquitin dependent pathway (By similarity). Specifically recognizes TP73, promoting its ubiquitination and degradation (By similarity).

Belongs to the FBXO45/Fsn family.

25.759 kDa

single

LASRALVCKHWYRCLHGDENSEVWRSLCARSLEEAMRTDILCNLPSYKAKVRAFQHAFSTNDCSRNVYIKKNGFTLHRNPIAQSTDGARTKIGFSEGRHAWEVWWEGPLGTVAVIGIATKRAPMQCQGYVALLGSDDQSWGWNLVDNNLLHNGEVNGSFPQCNNAPKYQIGERIRVILDMEDKTLAFERGYEFLGVAFRGLPKACLYPAVSAVYGNTEVTLVYLGKPLDG