FBXL22

F-box and leucine-rich protein 22

247 amino acids

Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. Promotes ubiquitination of sarcomeric proteins alpha-actinin-2 (ACTN2) and filamin-C (FLNC).

27.269 kDa

MWPLLTMHITQLNRECLLHLFSFLDKDSRKSLARTCSQLHDVFEDPALWSLLHFRSLTELQKDNFLLGPALRSLSICWHSSRVQVCSIEDWLKSAFQRSICSRHESLVNDFLLRVCDRLSAVRSPRRREAPAPSSGTPIAVGPKSPRWGGPDHSEFADLRSGVTGARAAARRGLGSLRAERPSETPPAPGVSWGPPPPGAPVVISVKQEEGKQGRTGRRSHRAAPPCGFARTRVCPPTFPGADAFPQ

Fbxl22

F-box and leucine-rich protein 22

236 amino acids

Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. Promotes ubiquitination of sarcomeric proteins alpha-actinin-2 (ACTN2) and filamin-C (FLNC) (By similarity).

26.32 kDa

MHITQLNRECLLCLFSFLDKDSRRSLSRTCSQLRDVFEDPTLWPLLHFHSLAELKKDNFRLSPALRSLSICWHSSRVQVCSIEDWLKSALQRSICSQHESLVNDFLLQVCNRCPNLTSVTLSGCGHVTDDCLARLLLSCPRLRTLRLENCARVTNRTLAAVAAHGRALQTLHVDFCRNVSAAGLLRLRAACPNLRLSAERSAAMIPDQPPRARVCAASAFSAAPGRQSMPHPTGSY

FBXL22

F-box and leucine-rich protein 22

226 amino acids

Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. Promotes ubiquitination of sarcomeric proteins alpha-actinin-2 (ACTN2) and filamin-C (FLNC) (By similarity).

25.507 kDa

MHITQLNRECLLHLFSFLDKDSRKNLARTCPQLQDVFEDPALWPLLHFRSLTELKKDNFLLSPALRSLSICWHSSRVQVCSIEDWLKSALQRNICSRHESLVNDFLLQVCDRCPNLASVTLSGCGHVTDDCLARLLRCCPRLRALHLENCARVTNRTLTAVAAHGRALQTLHVDFCRNVSAAGLRRLRAACPRLTLRAEHSAAMIPDQLPRGPHAPGAALRKLLLR