FBXL15

Gene

FBXL15

Protein

F-box/LRR-repeat protein 15

Organism

Canis lupus familiaris

Length

300 amino acids

Function

Similarity

Belongs to the FBXL15 family.

Mass

32.983 kDa

Sequence

MEPPMEPSGGEQEPGAVRLLDLPWEDVLLPHILSRVPLRQLLRLQRVSRAFRALVQLHLAGLRRFDAAQVGPQIPRAALAWLLRDAEGLQELALAPCHEWLSDEDLVPVLTRNPQLRSVALAGCGQLSRRALGALAEGCPRLQRLSLAHCDWVDGLALRGLADRCPALEELDLTACRQLKDEAIVYLAQRRGAGLRSLSLAVNANVGDAAVQELARNCPELEHLDLTGCLRVGSDGVRTLAEYCPALRSLRVRHCHHVAEPSLSRLRKRGVDIDVEPPLHQALVLLQDMAGFAPFVNLQV

Protein

Gene

FBXL15

Protein

F-box/LRR-repeat protein 15

Organism

Homo sapiens

Length

300 amino acids

Function

Similarity

Belongs to the FBXL15 family.

Mass

32.998 kDa

Sequence

MEPPMEPSGGEQEPGAVRFLDLPWEDVLLPHVLNRVPLRQLLRLQRVSRAFRSLVQLHLAGLRRFDAAQVGPQIPRAALARLLRDAEGLQELALAPCHEWLSDEDLVPVLARNPQLRSVALGGCGQLSRRALGALAEGCPRLQRLSLAHCDWVDGLALRGLADRCPALEELDLTACRQLKDEAIVYLAQRRGAGLRSLSLAVNANVGDAAVQELARNCPELHHLDLTGCLRVGSDGVRTLAEYCPVLRSLRVRHCHHVAESSLSRLRKRGVDIDVEPPLHQALVLLQDMAGFAPFVNLQV

Protein

Gene

Fbxl15

Protein

F-box/LRR-repeat protein 15

Organism

Mus musculus

Length

300 amino acids

Function

Similarity

Belongs to the FBXL15 family.

Mass

33.125 kDa

Sequence

MEPPMEQSGGEQEPGAVRLLDLPWEDVLLPHVLNWVPLRQLLRLQRVSRAFRALVQLHLARLRRFDAAQVGPQIPRAALARLLRDAEGLQELALAPCHEWLSDEDLVPVLARNPQLRSVALAGCGQLSRRALGALAEGCPRLQRLSLAHCDWVDGLALRGLADRCPALEELDLTACRQLKDEAIVYLAQRRGAGLRSLSLAVNANVGDTAVQELARNCPQLEHLDLTGCLRVGSDGVRTLAEYCPALRSLRVRHCHHVAEPSLSRLRKRGVDIDVEPPLHQALVLLQDMAGFAPFVNLQV

Protein

Gene

Fbxl15

Protein

F-box/LRR-repeat protein 15

Organism

Rattus norvegicus

Length

300 amino acids

Function

Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of SMURF1, thereby acting as a positive regulator of the BMP signaling pathway. Required for dorsal/ventral pattern formation. Also mediates ubiquitination of SMURF2 and WWP2 (By similarity). Required for bone mass maintenance.

Similarity

Belongs to the FBXL15 family.

Mass

33.18 kDa

Sequence

MEPPMEQSGGEQEPGAVRLLDLPWEDVLLPHVLNWVPLRQLLRLQRVSRAFRALVQLHLARLRRFDAAQVGPQIPRAALVRLLRDAEGLQELALAPCHEWLLDEDLVPVLARNPQLRSVALAGCGQLSRRALGALAEGCPRLQRISLAHCDWVDGLALRGLADRCPALEELDLTACRQLKDEAIVYLAQRRGAGLRSLSLAVNANVGDTAVQELARNCPQLEHLDLTGCLRVGSDGVRTLAEYCPALRSLRVRHCHHVAEPSLSRLRKRGVDIDVEPPLHQALVLLQDMAGFAPFVNLQV

Protein

Gene

FBXL15

Protein

F-box/LRR-repeat protein 15

Organism

Bos taurus

Length

300 amino acids

Function

Similarity

Belongs to the FBXL15 family.

Mass

33.152 kDa

Sequence

Protein

Gene

FBXL15

Protein

F-box/LRR-repeat protein 15

Organism

Canis lupus familiaris

Length

300 amino acids

Function

Similarity

Belongs to the FBXL15 family.

Mass

32.983 kDa

Sequence

Protein

Gene

FBXL15

Protein

F-box/LRR-repeat protein 15

Organism

Homo sapiens

Length

300 amino acids

Function

Similarity

Belongs to the FBXL15 family.

Mass

32.998 kDa

Sequence

Protein

Gene

Fbxl15

Protein

F-box/LRR-repeat protein 15

Organism

Mus musculus

Length

300 amino acids

Function

Similarity

Belongs to the FBXL15 family.

Mass

33.125 kDa

Sequence

Protein

Gene

Fbxl15

Protein

F-box/LRR-repeat protein 15

Organism

Rattus norvegicus

Length

300 amino acids

Function

Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of SMURF1, thereby acting as a positive regulator of the BMP signaling pathway. Required for dorsal/ventral pattern formation. Also mediates ubiquitination of SMURF2 and WWP2 (By similarity). Required for bone mass maintenance.

Similarity

Belongs to the FBXL15 family.

Mass

33.18 kDa

Sequence

Protein

Gene

fbxl15

Protein

F-box/LRR-repeat protein 15

Organism

Danio rerio

Length

296 amino acids

Function

Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Acts as a positive regulator of the BMP signaling pathway (By similarity). Required for dorsal/ventral pattern formation.

Similarity

Belongs to the FBXL15 family.

Mass

33.496 kDa

Sequence

MDQKPDERVQSHRCELLDLPWEDVLVSHVFCHLPLRLLVSLQRVSKSFRSLIQVYLDNCRTFDPAQTGPHIPREAFCSILRHNQVLQHLSVTNCSDWITDTDLLPVIGQNQQLQHVDLRGCAQLSRRALVAVSLSCPRLQHLSLAHCEWVDSLALRSLADHCPMLRSLDLTACRQLKDPAVCYLAGKCPELRALSVAVNANITDTAVEEVAKKCREMERLDLTGCLRVRNEAIRTLAEYCPKLQSLKVNHCHNVTESSLGVLRRRNVEIDVEPPLQRALVLLQDVVGFAPFINLQI

Protein

Gene

fbxl15

Protein

F-box/LRR-repeat protein 15

Organism

Danio rerio

Length

296 amino acids

Function

Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Acts as a positive regulator of the BMP signaling pathway (By similarity). Required for dorsal/ventral pattern formation.

Similarity

Belongs to the FBXL15 family.

Mass

33.496 kDa

Sequence

Protein

Gene

fbxl15

Protein

F-box/LRR-repeat protein 15

Organism

Dicentrarchus labrax

Length

292 amino acids

Function

Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Acts as a positive regulator of the BMP signaling pathway). Required for dorsal/ventral pattern formation (By similarity.

Similarity

Belongs to the FBXL15 family.

Mass

32.866 kDa

Sequence

MDEEAKIRTCQLLDLPWEDVLIPHILCYLPLQHLVSLQRVSKQFHSLIQVYLTNCRTFDLTSIGPSIPKEAFCSMLKDNKVLHSLSLQNCSDWVTDKELLPVIGQNQHLQRVDMSGCVCLTRHSLVAVSLSCMHLQHLGLAHCEWVDSLSLRSLADHCGGLQSIDLTACRQLKDDAICYLAKKCLKLRSLSLAVNANITDESVEEVAKNCRGLEQLDLTGCLRVRNQSIRTLAEYCPKLQSLKVNHCHNVTESSLDPLRKRNVVIDVEPPLQRALVLLQDVLGFAPFINLQI

Protein

Gene

fbxl15

Protein

F-box/LRR-repeat protein 15

Organism

Salmo salar

Length

292 amino acids

Function

Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Acts as a positive regulator of the BMP signaling pathway). Required for dorsal/ventral pattern formation (By similarity.

Similarity

Belongs to the FBXL15 family.

Mass

33.172 kDa

Sequence

MDAETECCKCHLLDLPWEDVLVTHIFCYLPLRQLVRLQRVSKQFYALIQVYLANCRTFDLTQIGPSLPKEAFCNILRDNKVLQNLSVQNCSDWVTDTELLPVIGQNQHLLRVDMRGCDRLTRHSLVAVSLSCTHLQYLGLAHCEWVDSLSIRSLADHCGGLRSIDLTACRQLKDEAICYLSKKCLKMRSLSVAVNANITDVSVEEVAKNCRELEQLDLTGCLRVRNDSIRTVAEYCPKLQSLKVNHCHNVTESSLDPLRKRNVEIDVEPPLQRALVLLQDVVGFAPFINLQI

Protein

Gene

fbxl15

Protein

F-box/LRR-repeat protein 15

Organism

Xenopus laevis

Length

292 amino acids

Function

Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Acts as a positive regulator of the BMP signaling pathway). Required for dorsal/ventral pattern formation (By similarity.

Similarity

Belongs to the FBXL15 family.

Mass

33.013 kDa

Sequence

MAKDEDNSRVHLLDLPWEDVLVPHILSYLPLRHILSLQRVSKPFHSLVHIYLCNCRHFDSTQLGPQLPKTTFSELLKNNTVLQKLDLQSCSDWLTDKELLPIIGQNHHLTYINLNSCGQLTRQSLVAISLSCPHLQNICLGHCDWVDCLSMRSLADHCKCLEAIDLTACRQLKDDAISYLVQKSTRLKSLSLAVNANISDIAVEETAKSCRDLEHLDLTGCLRVKNDSIRTLAEYCNNLKSLKVKHCHNVTESSLGNLRKREVVLDVEPPLQRALVLLQDVVGFAPFINLQI

Protein

Gene

fbxl15

Protein

F-box/LRR-repeat protein 15

Organism

Xenopus tropicalis

Length

292 amino acids

Function

Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Acts as a positive regulator of the BMP signaling pathway). Required for dorsal/ventral pattern formation (By similarity.

Similarity

Belongs to the FBXL15 family.

Mass

32.983 kDa

Sequence

MAKDEDNSSVHLLDLPWEDVLVPHILRNLPLRHILSLQRVSKPFQSLVHLYLANCRHFDSTQLGSQLPKSTFSELLRNNTVLQKLDLQSCCDWLTDKELLPVIGQNHHLIHINLNSCGQLTRQSLVAISLSCPHLQNICLGHCEWVDCLSLRSLVDHCKCLEAIDLTACRQLKDDTISYLVQKSTRLKSLSLAVNANISDIAVEETAKNCRDLEHLDLTGCLRVKNDSIRTLAEYCTKLKSLKVKHCHNVTESSLGNLRKREVVLDVEPPLQRALVLLQDVVGFGPFINLQI

Protein

Gene

fbxl15

Protein

F-box/LRR-repeat protein 15

Organism

Dicentrarchus labrax

Length

292 amino acids

Function

Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Acts as a positive regulator of the BMP signaling pathway). Required for dorsal/ventral pattern formation (By similarity.

Similarity

Belongs to the FBXL15 family.

Mass

32.866 kDa

Sequence

Protein

Gene

fbxl15

Protein

F-box/LRR-repeat protein 15

Organism

Salmo salar

Length

292 amino acids

Function

Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Acts as a positive regulator of the BMP signaling pathway). Required for dorsal/ventral pattern formation (By similarity.

Similarity

Belongs to the FBXL15 family.

Mass

33.172 kDa

Sequence

Protein

Gene

fbxl15

Protein

F-box/LRR-repeat protein 15

Organism

Xenopus laevis

Length

292 amino acids

Function

Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Acts as a positive regulator of the BMP signaling pathway). Required for dorsal/ventral pattern formation (By similarity.

Similarity

Belongs to the FBXL15 family.

Mass

33.013 kDa

Sequence

Protein

Gene

fbxl15

Protein

F-box/LRR-repeat protein 15

Organism

Xenopus tropicalis

Length

292 amino acids

Function

Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Acts as a positive regulator of the BMP signaling pathway). Required for dorsal/ventral pattern formation (By similarity.

Similarity

Belongs to the FBXL15 family.

Mass

32.983 kDa

Sequence

Protein