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FAU1

Gene
FAU1
Protein
5-formyltetrahydrofolate cyclo-ligase
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Length
211 amino acids
Function
Only enzyme known to utilize 5-formyltetrahydrofolate (folinic acid) as substrate. Contributes to tetrahydrofolate metabolism in an alternative way of folate biosynthesis. May regulate carbon flow through the folate-dependent one-carbon metabolic network that supplies carbon for the biosynthesis of purines, thymidine and amino acids.
Similarity
Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.
Mass
24.059 kDa
Sequence
MATKQLLRRQIKRVINALDYDIIAAESHTISQAVRSLIASANSRRVACYMSMDKGEVTTGEIIKNLFQDGQEVFLPRCTHTSESKHFKLREDHHPHLIFHRMSSLKMVRDLKPQGPYQLKEPEPHIEESDILDVVLVPGVAFDIKTGARMGHGAGYYDDFFQRYKILHEGQKPLLVGLCLMEQVASPIPLEKHDYSMDCIVCGDGSIHWFQ