FASTKD3

FAST kinase domain-containing protein 3, mitochondrial

662 amino acids

Required for normal mitochondrial respiration (PubMed:20869947). Increases steady-state levels and half-lives of a subset of mature mitochondrial mRNAs MT-ND2, MT-ND3, MT-CYTB, MT-CO2, and MT-ATP8/6. Promotes MT-CO1 mRNA translation and increases mitochondrial complex IV assembly and activity (PubMed:27789713).

Belongs to the FAST kinase family.

75.689 kDa

MALITLRKNLYRLSDFQMHRALAALKNKPLNHVHKVVKERLCPWLCSRQPEPFGVKFHHAHCKKFHSKNGNDLHPLGGPVFSQVSDCDRLEQNVKNEESQMFYRRLSNLTSSEEVLSFISTMETLPDTMAAGALQRICEVEKKDGDQGLPKEILENSIFQALCFQFEKEPSQLSNTSLVTALQALILLHVDPQSSLLLNLVAECQNRLRKGGMEVRNLCILGESLITLHSSGCVTLELIINQLQGEKLETFTPEDIVALYRILQACTEKVDEHQTFLNKINNFSLSIVSNLSPKLISQMLTALVVLDQSQAFPLIIKLGKYVVRHVPHFTNEELRRVLEAFIYFGHHDTFFTKALEHRVAAVCLTLDPEVVCRVMEYCSRELILSKPILNAVAETFVCQTEKFSPRQISALMEPFGKLNYLPPNASALFRKLENVLFTHFNYFPPKSLLKLLHSCSLNECHPVNFLAKIFKPLFLQRLQGKESHLDTLSRAQLTQLFLASVLECPFYKGPKLLPKYQVKSFLTPCCSLETPVDSQLYRYVKIGLTNLLGARLYFAPKVLTPYCYTIDVEIKLDEEGFVLPSTANEDIHKRIALCIDGPKRFCSNSKHLLGKEAIKQRHLQLLGYQVVQIPYHEIGMLKSRRELVEYLQRKLFSQNTVHWLQE

Fastkd3

FAST kinase domain-containing protein 3, mitochondrial

661 amino acids

Required for normal mitochondrial respiration. Increases steady-state levels and half-lives of a subset of mature mitochondrial mRNAs MT-ND2, MT-ND3, MT-CYTB, MT-CO2, and MT-ATP8/6. Promotes MT-CO1 mRNA translation and increases mitochondrial complex IV assembly and activity.

Belongs to the FAST kinase family.

75.317 kDa

MAFITLRRAFCHKSILWIPGAVVALKIHPASHAPKAVTDRLSVCFCSLQPELFRVRFHHAYCKNFHSEKGNDFHPVGEPWSSQAQEWNQPGQSLQNEDEEMLFRRLSYFTSFEEVLSFISALDTLPVPLAMAALLRICEIGRRDGEQRLPEGVLENRAFQALCLRCERDPSHLTNAGLVTALQSLLTLLPADPQSSLMLSLVAECQRRLQRGNLEVHHLCVLGESLAMLQGASCETLKLVVRQLQSKSVETFAPEEITSVYRILQVCPEEVDKHQMFLNTLNNFSISVVPYLSPKSISHVLTALVALDQTHALPLLIKLGKYVVRYIPRFTNEELRKVLEAFVYFGHSDRFFTEALEQHVSALCFSLDPAVASSVMGYCSRKRILSKPIFDVVSEIVVCQWDRLSPSQIAELIEPFGKLNYVPPNAPALFRKVENVLCARLHHFPPKMLLRLLHSCALIERHPVNFMSKLFSPFFLQRLQGKESYLDRLSLAQLTQLFLTSVLECPFYKGPKLLPKYQVKSFLTPCCSLETPLDLHLYKSVVIGLIDLLGSRLYFASKVLTPYYYTIDVEVKLDEDGFVLPCTVDEDIHKRVALCIDGPQRFCLDSKHLLGKEATKQRHLRLLGYQVVQLPYHELELLTSRLELVDYLQRKLFSQSSAVHW

FASTKD3

FAST kinase domain-containing protein 3, mitochondrial

660 amino acids

Required for normal mitochondrial respiration. Increases steady-state levels and half-lives of a subset of mature mitochondrial mRNAs MT-ND2, MT-ND3, MT-CYTB, MT-CO2, and MT-ATP8/6. Promotes MT-CO1 mRNA translation and increases mitochondrial complex IV assembly and activity.

Belongs to the FAST kinase family.

75.487 kDa

MALVTLRRNLYHLSDFRIHGALAALKTQQVNHVHKTVKEHLCPWFWSQHPGPIRVRFHHAHCKKFHSENGNDLHPVGEPGFSQVHNWDRFEHSVKNVDEQMFYRKLNSFTSSGEILRFVSTLETLPDTMMAGALHRICEVERKDGDQRLPKEILESSAFQALCDRFGRDPSDLSNAGLVTAFQALTLLCGDPQSHLLMNLEAECQHRLERGGLDVHSLCILGETLIKLHGPGCSTLDLIIYQLQGESLETFTPEDIVTVYRLLQASPEKADQQQRFLNKINHFSLSLVSNLSPKLMSQMLTALVVLDQTQALPLVIKLSKYVVRHIARFTSEELRKVLEALIYFGHSDRFFTETLEQHVASLCLTLDPELVSRVMEYCSRKLILSEPIFNAVAETFVCQAEKFSPSQTAKLIEPFGKLNYLPPNASALFRKLENMLLTRFNHFPPKTLLRLLHSCSLIESHPVNFMAKIFSPYFLQQLQGAESYLDRLSLAQLTQLFLTSILECPFYKGPKLLPKFQVKSFLTPCSSLETPMDFHLYKSVMIGLIDLLGARLYFSSKVLTPYCYTIDVEIKLDEDGFVLPFTIDEDVHKRVALCIDGPKRFCLNSKHLLGKEATKQRHLRLLGYQVVQIPYYEIEMLKSRLELVDYLQGKLFSQNSGGHW

Fastkd3

FAST kinase domain-containing protein 3, mitochondrial

656 amino acids

Required for normal mitochondrial respiration. Increases steady-state levels and half-lives of a subset of mature mitochondrial mRNAs MT-ND2, MT-ND3, MT-CYTB, MT-CO2, and MT-ATP8/6. Promotes MT-CO1 mRNA translation and increases mitochondrial complex IV assembly and activity.

Belongs to the FAST kinase family.

75.248 kDa

MAFTLRRAFCHMSVFWMPGAVVALKIHPANNVQKAVRDCLRVWFCSLQPDLFRVRFYHAYCKSFHSENGNDLHPVGEPWFSQAQVWNQPEQTLKNEDEEMLSRRLNSFASFEEVLSFIHTLDTLPVTLASAALLRICEIGKRDDEQRLPKEVLENRVFQALCLRCERDPSHLTNAVLVTVLQSLVIDPQSSLVLSLVAECQRRLRRGSLEVHHLCVLGESLARLQGASCEILKLVICQLQSENLETFAPEDIVSVYRILQACPEEVDKHQTFLNTVNNFSLSIVSYLSPKSISHVLTALVALDQTHARPLLIKLGKSVVRYIPRFTNEELRQVLEAFVYFGHSDRFFTEALEQHVAAQCFSLDPAVASSVMEYCSRKRILSKPIFDVVAEIFVCQSEKFSPSQISELIEPFGKLNYLPPNAPALFRKVENVLFAHLRHFPPKMLLRLLHSCSLIERHPVNFMSKIFSPFFLQRLQGKESYLDRLSLAQMTQLFLTSVLECPFYKGPKLLPKYQVKSFLTPCCSLETPMDLHLYKSVVIGLIDLLGSRLYFASKVLTPYYYTIDVEIKLDEDGFVLPFTVDEDVHTRVALCIDGPQRFCLGSKHLLGKEAIKQRHLRLLGYQVVQVPYHELELLTSRLELVDYLQRKLFSQSSTVHW