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FAM172A

Gene
fam172a
Protein
Cotranscriptional regulator FAM172A homolog
Organism
Xenopus tropicalis
Length
422 amino acids
Function
May play role in the regulation of alternative splicing. May have hydrolase activity.
Similarity
Belongs to the FAM172 family.
Mass
48.981 kDa
Sequence
MKLEIKCFIICKVLPLVWLNMAQIQQVGAPEEKEKTTALKDLLSRIDLDELMKKDEPPLEFPDTLEGFNYAFNELGQLRHIQTGDPFVFNYREDLHRWNQKRYEALGEIITKHVYELLEKDCELEKVYLPVDATDSEPRSFIFMSKDAMTNPDKMLVLIHGSGVVRAGQWARRLIINEDLNSGSQIPYIKRAMKEGYAVIVLNPNENYIEVEKSKVPADQPSPDSSDEPAEKRERRERNPKETKKRRDFYEKYRNPQKEKETLQVYIRDNGSPEEHALYVWDNFISKAAAENILFVAHSYGGLTFVELMIQREADVKNKVAAVALTDSVHNVWHQDASKTLREWMRENCCNWVSSSEPLDTSVESTLPDCPRVSAGTERHELTSWKSFHSIFKFFDDALQAKNTKTKPTPTRRSNRIKHEDL
Protein
Cotranscriptional regulator FAM172A homolog: fam172a

Gene
Fam172a
Protein
Cotranscriptional regulator FAM172A
Organism
Mus musculus
Length
417 amino acids
Function
Plays a role in the regulation of alternative splicing, by interacting with AGO2 and CHD7. Seems to be required for stabilizing protein-protein interactions at the chromatin-spliceosome interface (PubMed:29311329). May have hydrolase activity (PubMed:29311329).
Similarity
Belongs to the FAM172 family.
Mass
48.072 kDa
Sequence
MSISLSSLIFLPIWINMAQMQQGGSNETEQTAALKDLLSRIDLDELMKKDEPPFDFPDTLEGFEYAFNEKGQLRHIKTGEPFVFNYREDLHRWNQKRYEALGEIITRYVYELLESDCNLKKISIPVDATESEPKSFIFMSEDALTNPQKLMVLIHGSGVVRAGQWARRLIINEDLDSGTQIPFIKRAMDEGYGVIVLNPNENYIEVEKQKMHKQSSSSDGTDEPAGKRERRDKVSKETKKRRDFYEKYRNPQKEKEMMQLFIRENGSPEEHAVYVWDHFIAQAAAENVFFVAHSYGGLAFVELMIQREADVKSKVTAVALTDSVHNVWHQEAGKTIREWMRENCCNWVSSSEPLDTSVESMLPDCPRVSAGTDRHELTSWKSFPSIFKFFAEASEAKSSSQKPALTRRSHRIKHEEL
Protein
Cotranscriptional regulator FAM172A: Fam172a

Gene
FAM172A
Protein
Cotranscriptional regulator FAM172A homolog
Organism
Gallus gallus
Length
416 amino acids
Function
May play role in the regulation of alternative splicing. May have hydrolase activity.
Similarity
Belongs to the FAM172 family.
Mass
48.354 kDa
Sequence
MHFYFNVLNLLTVWVMMAQLQQGVPDEKEKTTALKDLLSRIDLDELMKKDEPPLEFPDTLEGFEYSFNEKGQLRHAKTGEPFVFNYREDLHRWNQKRYEALGEIITKHVYGLLEKECHLKKVTLPVDATENEPKSFIFMSEDALTNPDKLLVLIHGNGVVRAGQWARRLIINEDLDSGTQIPYIKKATEEGYGVIVLNPNENYIEVEKTKAQVQLSSDSSDEPAEKRERKDKIQKETKKRRDFYEKYRNPQKEKETMQMYIRDNGSPEEHAIYVWDHFISQSAAENVFFVAHSYGGLAFVELMIQRETEVKNKVTAVALTDSVHNVWHQEAGKTIREWMRENCCNWVSSSEPLDTSVESMLPDCPRVSAGTERHELTSWKSFPSIFKFFSEAMEAKNSSVKPAPTRRSNRIKYEEL
Protein
Cotranscriptional regulator FAM172A homolog: FAM172A

Gene
FAM172A
Protein
Cotranscriptional regulator FAM172A
Organism
Homo sapiens
Length
416 amino acids
Function
Plays a role in the regulation of alternative splicing, by interacting with AGO2 and CHD7. Seems to be required for stabilizing protein-protein interactions at the chromatin-spliceosome interface. May have hydrolase activity.
Similarity
Belongs to the FAM172 family.
Mass
47.972 kDa
Sequence
MSISLSSLILLPIWINMAQIQQGGPDEKEKTTALKDLLSRIDLDELMKKDEPPLDFPDTLEGFEYAFNEKGQLRHIKTGEPFVFNYREDLHRWNQKRYEALGEIITKYVYELLEKDCNLKKVSIPVDATESEPKSFIFMSEDALTNPQKLMVLIHGSGVVRAGQWARRLIINEDLDSGTQIPFIKRAVAEGYGVIVLNPNENYIEVEKPKIHVQSSSDSSDEPAEKRERKDKVSKETKKRRDFYEKYRNPQREKEMMQLYIRENGSPEEHAIYVWDHFIAQAAAENVFFVAHSYGGLAFVELMIQREADVKNKVTAVALTDSVHNVWHQEAGKTIREWMRENCCNWVSSSEPLDTSVESMLPDCPRVSAGTDRHELTSWKSFPSIFKFFTEASEAKTSSLKPAVTRRSHRIKHEEL
Protein
Cotranscriptional regulator FAM172A: FAM172A

Gene
fam172a
Protein
Cotranscriptional regulator FAM172A homolog
Organism
Danio rerio
Length
415 amino acids
Function
May play role in the regulation of alternative splicing. May have hydrolase activity.
Similarity
Belongs to the FAM172 family.
Mass
48.208 kDa
Sequence
MFFRASFFLFGLVWITMAQLLAQDEKEKTTALKDLLSRIDLDELMKKDEPPLDFPETLDGFEYAFNEQGQLRHTKTGEPFVFNYKEDLHRWNQKRYEALGEIITKYVYERLEKDCNLKKEILPVDATEDEPKSFIYVSEDALSNPDKIMVLIQGSGVVRAGQWARRLIINEDLNSGTQIPFINRAKEEGYGVIVLNPNENSLEVEKVSDPAKKASPDASDEPAEKRERKEERENKKKKDFYEKYRNPQKEREMEHIPIRENGSPEEHTLYAWDYFISKSLAKNIFIVAHSYGGLSFVNLMINREAEVKSRVRAVAMTDSVHNVWHQEASKSIQDWLREHCCNWVSSPEPLDTLVDPMLNDCPRVSAGTEKHELTSWKSFQSIFKFFSNALKDHEDDSSSSPVTTRSSHRIKHEDF
Protein
Cotranscriptional regulator FAM172A homolog: fam172a