FAC

Gene

FAC

Protein

Bifunctional fatty acid conjugase/Delta(12)-oleate desaturase

Organism

Trichosanthes kirilowii

Length

387 amino acids

Function

Converts a single cis double bond at position 12 of linoleate incorporated into phosphatidylcholine into conjugated 11-trans and 13-cis double bonds (PubMed:12464604). 16:2(9Z,12Z), 18:3(9Z,12Z,15Z) and 18:2(9Z,12Z) are substrates for the conjugase to form trans-Delta(11) and cis-Delta(13) double bonds (PubMed:12464604). No activity on the cis-Delta(9) double bonds of oleic and palmitoleic acids (PubMed:12464604).

Similarity

Belongs to the fatty acid desaturase type 1 family.

Mass

44.918 kDa

Sequence

MGGGEGIEVRSGSSSTKLAFGERITHAKPPFSISQIKKAIPPHCFQRSLYRSFSYVIFDFIFASTFYHIAATNFHRLPHPLHYLAWPLYWFCQGSVFTGLWVIAHECGHRAFSDYQLVDDVVGFLLHTSFLIPYFSFKISHRRHHSNTASLERDEVFVPKPKAKMPWYFKHLTNPPARVLIIFITLTLGWPMYLAFNISGRFYERFTSHFDPNSPIFSENEWLQVHISNAGIVAVWYLLYKLAAAKGIAWVIRMYVVPVTIMNAFVVLITSLQHTHPSFPYYDSTEWNWLRGNLVTLDRDYGILNKVFHNITDTHVVHHLFPSMPHYNAMEATRAVKQVLGEYYHFDGTPIFKAAWREFRECIYVEPDNDEGASSSSKGVFWFRNKL

Protein

Bifunctional fatty acid conjugase/Delta(12)-oleate desaturase: FAC