F6H2-1-8

Gene

F6H2-1-8

Protein

Bi-functional coumaroyl CoA and feruloyl CoA ortho-hydroxylase F6H2-1-8

Organism

Ipomoea batatas

Length

359 amino acids

Function

2-oxoglutarate (OG)- and Fe(II)-dependent dioxygenase (2OGD) involved in scopoletin and umbelliferone biosynthesis (PubMed:22169019). Converts feruloyl CoA into 6'-hydroxyferuloyl CoA, and p-coumaroyl CoA into 2,4-dihydroxycinnamoyl-CoA, but has no activity with caffeoyl-CoA (PubMed:22169019).

Similarity

Belongs to the iron/ascorbate-dependent oxidoreductase family.

Mass

40.515 kDa

Sequence

MMPSTTLSTVLSDINEFVVKQGHGVKGLSELGLQTLPNQYVHPPEERLSSMDVVSDDSIPVIDVSNWEDPKVAKLICNAAEKRGFFQIVNHGIPLEMLEKAKAATYRFFREPAQEKKKYSKENCPTSHVRYSTSFLPQIEKALEWKDHLSMFYVSDQEAAQYWPPSCRDDALEYLKSCELVSRKLLEALMQGLNVNQIDDSKESLLMGSRRININYYPKCPNPDLTVGVGRHSDISTLTLLLQDDIGGLYVRKLEHEAWSHVPPVKGALVINIGDALQIMSNGRYKSIEHRVMANESNDRISVPVFVNPKPNDIVGPLPEVLASGEKPVYKPVLYSDYAKHFYRKAHNGKDTIAFARIE

Protein

Bi-functional coumaroyl CoA and feruloyl CoA ortho-hydroxylase F6H2-1-8: F6H2-1-8