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EthD

Gene
EthD
Protein
Conidial pigment biosynthesis dehydratase EthD
Organism
Metarhizium robertsii (strain ARSEF 23 / ATCC MYA-3075)
Length
142 amino acids
Function
Dehydratase; part of the Pks1 gene cluster that mediates the biosynthesis of an anthraquinone derivative pigment that contributes to conidial pigmentation that provides protection from UV radiation, heat and cold stress (PubMed:28447400). The polyketide synthase Pks1 produces 1-acetyl-2,4,6,8-tetrahydroxy-9,10-anthraquinone though condensation of acetyl-CoA with malonyl-CoA (Probable). The dehydratase EthD and the laccase Mlac1 further convert the anthraquinone derivative into the final conidial pigment (Probable).
Similarity
Belongs to the tpcK family.
Mass
16.524 kDa
Sequence
MAISDSVSPEPQQLLCLTITAFRKPGMSEAAYREYMTKTHAPLVSGLMEEYGIVRYNMTHNNSKSRPLLFQLYDPEFSKLSDYDCIVQFVFRRMEDFLRMKSDPRFLEKVAPDHQKFADTSRSTMTIGYFEEFLENGKVVPK