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ERD2

Gene
ERD2
Protein
ER lumen protein-retaining receptor
Organism
Plasmodium falciparum (isolate 3D7)
Length
221 amino acids
Function
Required for the retention of luminal endoplasmic reticulum proteins. Determines the specificity of the luminal ER protein retention system. Also required for normal vesicular traffic through the Golgi (By similarity).
Similarity
Belongs to the ERD2 family.
Mass
26.447 kDa
Sequence
MNIFRLIGDILHLVSMYILIMKLKKSKNCIGISCRMQELYLIVFLCRYIDLFFVFVSFYNTVMKITFILTIAYTIYLIRLKLPISQTYNRKVDNFKSEKYLIPPCLVLSLLTCKTYNLYNILWSFSIWLESVAILPQLVLLEKQREVENITSHYVITMGLYRAFYILNWIYRYFFDDKPYINVVGWIGGLIQTLLYIDFFYYFALAKWYGKKLVLPFNGEV

Gene
ERD2
Protein
ER lumen protein-retaining receptor
Organism
Plasmodium falciparum
Length
221 amino acids
Function
Required for the retention of luminal endoplasmic reticulum proteins. Determines the specificity of the luminal ER protein retention system. Also required for normal vesicular traffic through the Golgi (By similarity).
Similarity
Belongs to the ERD2 family.
Mass
26.447 kDa
Sequence
MNIFRLIGDILHLVSMYILIMKLKKSKNCIGISCRMQELYLIVFLCRYIDLFFVFVSFYNTVMKITFILTIAYTIYLIRLKLPISQTYNRKVDNFKSEKYLIPPCLVLSLLTCKTYNLYNILWSFSIWLESVAILPQLVLLEKQREVENITSHYVITMGLYRAFYILNWIYRYFFDDKPYINVVGWIGGLIQTLLYIDFFYYFALAKWYGKKLVLPFNGEV

Gene
ERD2
Protein
ER lumen protein-retaining receptor
Organism
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)
Length
219 amino acids
Function
Required for the retention of luminal endoplasmic reticulum proteins. Determines the specificity of the luminal ER protein retention system. Also required for normal vesicular traffic through the Golgi. This receptor recognizes H-D-E-L and D-D-E-L, but not K-D-E-L.
Similarity
Belongs to the ERD2 family.
Mass
25.851 kDa
Sequence
MLNVFRIAGDFSHLASIIILIQSITTSNSVDGISLKTQLLYTLVFITRYLNLFTKWTSLYNFLMKIVFISSSVYVIVLMRQQKFKNPVAYQDMITRDQFKIKFLIVPCILLGLIFNYRFSFIQICWSFSLWLESVAILPQLFMLTKTGKAKQLTSHYIFALGLYRALYIPNWIWRYYTEERFDKLSVFTGVIQTLVYSDFFYIYYQKVIKLGGDLELPQ

Gene
ERD2
Protein
ER lumen protein-retaining receptor
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Length
219 amino acids
Function
Required for the retention of luminal endoplasmic reticulum proteins. Determines the specificity of the luminal ER protein retention system. Also required for normal vesicular traffic through the Golgi. This receptor strongly recognizes H-D-E-L and weakly recognizes D-D-E-L and K-D-E-L.
Similarity
Belongs to the ERD2 family.
Mass
25.763 kDa
Sequence
MNPFRILGDLSHLTSILILIHNIKTTRYIEGISFKTQTLYALVFITRYLDLLTFHWVSLYNALMKIFFIVSTAYIVVLLQGSKRTNTIAYNEMLMHDTFKIQHLLIGSALMSVFFHHKFTFLELAWSFSVWLESVAILPQLYMLSKGGKTRSLTVHYIFAMGLYRALYIPNWIWRYSTEDKKLDKIAFFAGLLQTLLYSDFFYIYYTKVIRGKGFKLPK

Gene
ERD2
Protein
ER lumen protein-retaining receptor
Organism
Entamoeba histolytica
Length
215 amino acids
Function
Required for the retention of luminal endoplasmic reticulum proteins. Determines the specificity of the luminal ER protein retention system. Also required for normal vesicular traffic through the Golgi (By similarity).
Similarity
Belongs to the ERD2 family.
Mass
25.724 kDa
Sequence
MVFNLFRISADLVHLLSIYFLLTKIISHKNCIGISLRSQILFFIVWVTRYLDIFYNFYSLYNTILKIVYLTTSAYTIYLISKRFRATYDKIHDTLNVWYLIVPCIVLAFIFTEDYSITEICWTFSIFLEAVAILPQILLLRSTGEVENLNSQYIFCLGLYRALYIINWIYRYATEQSYWSPLTWICGSIQTLLYVEYFYYYIKSRVEGTKFVLPY

Gene
ERD2
Protein
ER lumen protein-retaining receptor
Organism
Petunia hybrida
Length
215 amino acids
Function
Required for the retention of luminal endoplasmic reticulum proteins. Determines the specificity of the luminal ER protein retention system. Also required for normal vesicular traffic through the Golgi. This receptor recognizes H-D-E-L (By similarity).
Similarity
Belongs to the ERD2 family.
Mass
25.602 kDa
Sequence
MNIFRLAGDMTHLASVLVLLLKIHTIKSCAGVSLKTQELYALVFVTRYLDIFTDFISLYNTTMKLVFLGSSLSIVWYMRHHKIVRRSYDKDQDTFRHLFLVLPCLLLALVINEKFTFKEVMWTFSIYLEAVAILPQLVLLQRTRNIDNLTGQYIFLLGAYRSFYILNWVYRYFTEPHFVHWITWIAGLIQTLLYADFFYYYFQSWKNNTKLELPA

Gene
erd2
Protein
ER lumen protein-retaining receptor
Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843)
Length
212 amino acids
Function
Required for the retention of luminal endoplasmic reticulum proteins. Determines the specificity of the luminal ER protein retention system. Also required for normal vesicular traffic through the Golgi (By similarity).
Similarity
Belongs to the ERD2 family.
Mass
24.725 kDa
Sequence
MTFFSALGDMAHLAAIFLLLHRMKKSKTCSGLSLKSHLLFLLVYVTRYLNLFWRYKSLYYFLMRIVFIASESYICYLMLMTLRPTYDKRLDTFRTEYILGGCAVLALIYPTSYTISNILWTFSIWLESVAILPQLFMLQRSGETESLTAHYLFAMCLYRGLYIPHWIYRIAVHKKVIGVAILAGIIQTVLYGDFAVVYRRTVLQGKKFRLPA