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ENV10

Gene
ENV10
Protein
SRP-independent targeting protein 2
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Length
181 amino acids
Function
Functions in the SND pathway, a SRP (signal recognition particle) and GET (guided entry of tail-anchored proteins) independent pathway for targeting a broad range of substrate proteins to the endoplasmic reticulum. SND functions in parallel to GET in targeting proteins with downstream hydrophobic motifs (PubMed:27905431). Involved in vacuolar processing and morphology (PubMed:21912603).
Similarity
Belongs to the TMEM208 family.
Mass
20.742 kDa
Sequence
MAGKAGRKQASSNAKIIQGLYKQVSLFLGMAIVRLFISRKVTIGQWIKLVALNVPMFVALYIIVLSGKPKYDGNRVVKQGIDLNDNTNLISYFFDLIYLSLFGNIGIIAFRTFKFWWCLLLCPIYAGYKLYGLKNMFMPGAQQTQADNRSKNANEGQSKSKRQMKRERRGETDSKIKYKYR