Protein
Elongator complex protein 5
Organism
Rattus norvegicus
Function
Acts as subunit of the RNA polymerase II elongator complex, which is a histone acetyltransferase component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. Elongator may play a role in chromatin remodeling and is involved in acetylation of histones H3 and probably H4. Involved in cell migration. May be involved in TP53-mediated transcriptional regulation (By similarity).
Similarity
Belongs to the ELP5 family.
Sequence
MPRLLSGDDIRRRPEASEMLDSLLATGGLVLLRDSVEWEGRGLLKALIKKSALRGEQVHVLGCEVSEEEFREGLGSDVNSRLVYHDLFRDPLNWSQPGEAAPEGPLKALRSMCRRTDRGSVTIALDSLSWLLCHIPCVTLCQALHALSQRNVDPGDNPLIEQVRVLGLLHEELHGPGPVGAVSSLAHTEVTLSGKMDQTSASILCRRPQQRATYQTWWFSILPDFSLDLHEGLPLHSELHRDPHTTQVDPASHLTFNLHLSKKEREAKDSLTLPFQFSSEKQQALLHPVPGQTTGRIFYEPDAFDDVDQEDPDDDLDI