Protein
TATA-box-binding protein 2
Organism
Entamoeba histolytica
Function
General transcription factor that functions at the core of the DNA-binding multiprotein factor TFIID. Binding of TFIID to the TATA box is the initial transcriptional step of the pre-initiation complex (PIC), playing a role in the activation of eukaryotic genes transcribed by RNA polymerase II.
Similarity
Belongs to the TBP family.
Sequence
MSQLGNICHADYMSTSTESQERSLNNPNDTHPEIVNVVSTFQLGVKLELRKIVQKARNAEYNPKRFAGAIMRISSPKSTALIFQTGKIVCTGTRSIEESKIASKKYAKIIKKIGYPIHYSNFNVQNIVGSCDVKFQIALRTLVDSYLAFCQYEPEVFPGLVYRMASPKVTLLVFSTGKVVLTGAKDEESLNLAYKNIYPILLANRKEDISNQ